10 Face Serums That Will Banish Fine Lines and Wrinkles

BY Janeca Racho · September 20, 2019

best wrinkle serums 2

We can’t completely stop wrinkles and fine lines in their tracks, but with the help of face serums, we can definitely slow down their advances. These skin care MVPs can effectively enhance your skin care regimen with their versatility and variety: They can be added to moisturizers, night creams and masks to enhance potency, be used as a spot treatment or as standalone actives that target just about every skin concern.

But with all the different types and ingredients available—and all the hype that comes with new releases and cult products—it can be difficult to figure out which bottle can give your skin that much-needed rejuvenation. Hence, it’s important to understand the specific needs of your skin and how time, the environment and your lifestyle affects it.

How Wrinkles and Fine Lines Form

Fine lines and wrinkles are all part of the natural aging process as skin gets thinner, drier and less elastic with age, says board-certified dermatologist Rhonda Klein. As early as your mid- to late-twenties, the production of the proteins collagen and elastin—the building blocks of healthy skin—slows down. Because they are being broken down faster than new ones are produced, it triggers the aging process that results in a dull complexion, sagging skin and folds and creases.

External or environmental factors also play a role. Pollution, UV radiation and certain lifestyle habits like smoking all accelerate and contribute to the degradation of your skin’s healthy cells and connective tissues, with some parts getting thicker and other thinner, adds scientist, author and skin care expert Dr. Hannah Sivak. “At the molecular level, there are many changes in protein structures. Some proteins are being broken down and replaced with others that are different in amino acid sequence and physical behavior,” explains Sivak.

How Serums Help 

Unlike creams and lotions, serums are also able to go deeper into the skin’s layers, says Heather Bennett, esthetician at Beverly Hills Rejuvenation Center. “Anti-wrinkle serums are more liquid than solid and therefore are able to penetrate multiple layers of skin more quickly and easily. The major benefits of serums are that they offer the most lightweight formula and give the most intensive results,” adds Bennett.

“Anti-aging serums and creams can help reduce environmental toxins, build collagen and elastin and smooth fine lines and wrinkles,” adds Dr. Klein. But aside from reversing the changes caused by aging, serums can also help prevent premature wrinkles and fine lines from developing, says Dr. Sivak. “There are many ingredients that can prevent oxidation and modification of cellular components, including the very important DNA mutations caused by UV radiation,” Dr. Sivak explains. “Other ingredients can prevent lipid oxidation, preserving cellular integrity.”

What Ingredients to Look For

Identifying your skin’s specific needs is the best way to choose an anti-aging serum. Below is a rundown of the best anti-aging serum ingredients that will plump up your skin, boost its defenses against environmental aggressors and keep those dreaded signs of aging at bay.

  • Vitamin C—Known for its essential role in boosting collagen synthesis, vitamin C—in higher, unbuffered concentrations—can also work as an effective exfoliator and renew the topmost layers of the skin, leaving you with a brighter complexion, says Dr. Sivak. It’s also a potent antioxidant, adds Dr. Klein. “[Vitamin C] can help reduce skin damage caused by free radicals, thereby reducing fine lines and wrinkles and improving texture,” she explains.
  • Hyaluronic Acid—As a potent humectant or moisture-binding ingredient, hyaluronic acid helps the skin retain moisture and induces collagen remodeling, leading to plump, hydrated skin, says Dr. Klein.
  • Peptides—A high concentration of peptides in a serum will help stimulate the growth of collagen and elastin, explains Dr. Klein. This results in the skin’s increased strength and elasticity, encourages skin healing and remodeling and smooths away fine lines and wrinkles.
  • Epidermal Growth Factor—Epidermal growth factor is a molecular chain of amino acids that aids in healing and wound recovery. It works by stimulating tissue repair and cell growth at a cellular level as well as encouraging the formation of collagen and elastin fibers, explains Dr. Klein.
  • Stem Cell—While stem cells can’t actually regenerate your skin or magically erase wrinkles, they do contain powerful antioxidant and anti-inflammatory properties, says Dr. Klein. “This helps protect your skin against sun damage, prevent wrinkles and induce collagen synthesis,” she adds.
  • Retinol/Vitamin A—“Retinoids bind to nuclear receptors and modify gene expression,” says Dr. Sivak. They are considered the rockstars of anti-aging skin care because of their ability to “minimize the appearance of wrinkles, bolster skin’s thickness and elasticity and slow the breakdown of collagen,” adds Dr. Klein. They also help in lightening brown spots or pigmentation caused by sun exposure.
  • AHAs—Alpha hydroxy acids like glycolic and lactic acids are primarily used as exfoliants but can also “promote collagen synthesis, correct discoloration and improve the appearance of lines and wrinkles,” explains Dr. Klein. They are also effective acne treatments and can help improve product absorption.
  • Vitamin E—This lipid-soluble antioxidant helps “protect cellular membranes from the damage done by free radicals, breaking the chain reactions initiated by them,” explains Dr. Sivak. It’s one of the most hardworking skin care ingredients, aiding in the prevention of photodamage, reduction of scars and plumping up the skin to diminish fine lines and wrinkles, adds Dr. Klein.
  • Niacinamide/Vitamin B3—This potent anti-aging ingredient can “visibly improve the appearance of enlarged pores, uneven skin tone, fine lines and dullness,” says Dr. Klein. “It may even reduce the incidence of non-melanoma skin cancers in high-risk patients.”
  • Soy Isoflavones—According to Dr. Sivak, these phytoestrogens “can help reduce the appearance of wrinkles caused by a decrease in hormone concentration during menopause.”
  • ResveratrolFound in the skin of red grapes (and red wine!), resveratrol is “a powerful antioxidant that reduces oxidative stress and irritation,” says Dr. Sivak. In high concentrations, it can help improve the skin’s elasticity, radiance and firmness.

Best Anti-Aging Serums

Say goodbye to fine lines and wrinkles and give your daily skin care regimen a boost with our top recommended anti-aging serums, below.

1. SkinCeuticals C E Ferulic

There’s a reason this serum has been getting hundreds of five-star reviews on Dermstore! Aside from vitamin E and ferulic acid, this antioxidant powerhouse also contains 15-percent pure l-ascorbic acid or vitamin C, making it truly worthy of its holy grail status. With a super-concentrated formula that’s effective for up to 72 hours, this serum enhances the skin’s defenses against oxidative stress and UV rays, smoothens lines and wrinkles and improves firmness and complexion.

2. SkinMedica TNS Essential Serum

When it comes to restoring your skin’s youthful glory, this serum is definitely not holding back. Featuring a dual-action formula that combines peptides, amino acids and antioxidants, it reduces inflammation, lifts and firms sagging skin and refines wrinkles and other signs of aging.

3. Sunday Riley Good Genes All-in-One Lactic Acid Treatment

Thank your stars if you’ve won the genetic lottery and have never spent a day in your life worrying about dryness or breakouts. Whether you were born with good genes or not, clear and radiant skin is within reach with this gentle serum featuring five-percent purified-grade lactic acid that works to clear skin and enhance collagen production. It also contains licorice, lemongrass and aloe, which reduce hyperpigmentation, boost radiance and soothe and refresh your complexion.

4. iS Clinical Active Serum

Featuring salicylic acid and herbal extracts, this multitasking serum works hard in providing anti-aging, anti-acne and brightening benefits by reducing hyperpigmentation, fine lines and wrinkles, redness and inflammation.

5. Estée Lauder Advanced Night Repair Synchronized Recovery Complex II

We all know the importance of beauty rest if you want to maintain a healthy complexion. Infused with caffeine, vitamin E, squalene oil and probiotics, this anti-aging treatment takes advantage of your skin’s natural nighttime renewal process using the brand’s trademarked ChronoluxCB™ Technology that diminishes the most common signs of aging.

6. Obagi Professional-C Serum 15%

Specially formulated to penetrate deep into your skin, this serum features L-ascorbic acid, or vitamin C, to effectively shield skin from sun damage, brighten hyperpigmentation and stimulate growth of collagen and elastin fibers. It’s also infused with hyaluronic acid to keep skin plump and hydrated.

7. Eminence Organic Skin Care Strawberry Rhubarb Hyaluronic Serum

Sagging skin and loss of firmness are some of the most noticeable signs of skin aging, but they can easily be prevented with this botanically powered serum. Hyaluronic acid plumps up sagging facial contours and boost your skin’s hydration, while salicylic acid from strawberry gently removes debris from your pores to prevent breakouts and even out your complexion. It also features a potent BioComplex that includes antioxidant boosters and coenzyme Q10 and extracts from rhubarb, aloe vera and honey that address fine lines and wrinkles and soothe and refresh skin.

8. PCA Skin Hyaluronic Acid Boosting Serum

This ultra-moisturizing face serum may be just the game-changer your skin is looking for. With its potent skin-perfecting formula that blends ceramides, niacinamide and a proprietary hyaluronic acid complex, it repairs and strengthens the skin’s natural barrier, plumps away fine lines and delivers up to 24 hours of hydration.

9. NEW! IMAGE Skincare VITAL C Hydrating Anti-Aging Serum

Pollution and sun damage are two of the top causes of premature skin aging, so it’s wise to keep this skin-renewing serum in your arsenal. Powered by potent antioxidants like vitamin E, resveratrol, green tea and tetrahexyldecyl ascorbate (a more stable form of vitamin C), it improves the appearance of wrinkles and crepey skin, encourages cell repair and shields your skin against free radical damage.

10. Juice Beauty GREEN APPLE™ Age Defy Serum

This brightening serum does more than restore your skin’s radiance and fade discoloration. Featuring a skin-rejuvenating blend of organic fruit juices, potent peptides, essential fatty acids, antioxidants and AHAs and BHAs, this wrinkle-fighting serum helps refine the appearance of fine lines and creases, firm and improve texture and protect your skin from pollution and other environmental aggressors.

Janeca Racho

With over 10 years of writing and editing experience, Janeca Racho has worked with clients in the fashion, entertainment, food, health and travel industries. An adventurer at heart, she will gladly trade her heels for ... Read More >

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