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iS Clinical Active Serum (1 fl. oz.)
A multi-tasking face serum that improves the appearance of aging, acne-prone and dull complexions.
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4 installments of $35.50 with Klarna Learn more
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4 installments of $35.50 with afterpay Learn more
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4 installments of $35.50 with sezzle Learn more
[music playing] is clinical active serum. Showing a bottle with a pipette and a snowy city landscape. Multitasking face serum, 1. anti-aging 2. anti-acne 3. brightening. Showing a lady apply to her face. Clean formula, glycerin, salicylic acid, herbal extracts. Softens skins texture. Curated. Top Rated. Authenticated. Dermstore.
iS Clinical Active Serum provides anti-aging, anti-acne and brightening benefits. Clinically-proven to provide both instant and long-term results, this face serum smooths away fine lines and wrinkles while softening the skin's texture. It reduces the appearance of hyperpigmentation, redness and acne, leading to a clearer and healthier-looking complexion.
Apply sparingly to clean skin, smoothing over face and neck (or as directed). This "active" product will produce a slight tingling sensation, which should dissipate within a few minutes.
Acne: Blackheads, Whiteheads
Aging Skin: Fine Lines and Wrinkles, Loss of Firmness
Application Area: Face
Ideal for these Concerns: Acne, Free Radical Damage, Hyperpigmentation, Redness
Ingredient: Herbal Extracts, Salicylic Acid
Preferences: Clean, Dermatologist Approved, Paraben-Free, Phthalate-Free, Sulfate-Free
Skin Care: Skin Care Treatments
Skin Care Treatments: Face Serums
Skin Type: Acne-Prone Skin, Combination Skin, Mature Skin, Oily Skin
Water/Aqua/Eau, Glycerin, Butylene Glycol, Alcohol Denat., Saccharum Officinarum (Sugarcane) Extract [Extrait de canne à sucre], Vaccinium Myrtillus Fruit/Leaf Extract, Triethanolamine, Salix Alba (Willow) Bark Extract, Glyceryl Polyacrylate, Arbutin, Polyporus Umbellatus (Mushroom) Extract, Menthol, Phenoxyethanol
Frequently Bought Together



Total Price: $300.00
Add both to cart
iS Clinical Active Serum (1 fl. oz.)
A multi-tasking face serum that improves the appearance of aging, acne-prone and dull complexions.
Earn 710 reward points when purchasing this product as a rewards member*
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Free delivery
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You control the frequency
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Payment will be taken every month. months.
$142.00
In stock
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4 installments of $35.50 with Klarna Learn more
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4 installments of $35.50 with afterpay Learn more
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4 installments of $35.50 with sezzle Learn more
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[music playing] is clinical active serum. Showing a bottle with a pipette and a snowy city landscape. Multitasking face serum, 1. anti-aging 2. anti-acne 3. brightening. Showing a lady apply to her face. Clean formula, glycerin, salicylic acid, herbal extracts. Softens skins texture. Curated. Top Rated. Authenticated. Dermstore.
iS Clinical Active Serum provides anti-aging, anti-acne and brightening benefits. Clinically-proven to provide both instant and long-term results, this face serum smooths away fine lines and wrinkles while softening the skin's texture. It reduces the appearance of hyperpigmentation, redness and acne, leading to a clearer and healthier-looking complexion.
Apply sparingly to clean skin, smoothing over face and neck (or as directed). This "active" product will produce a slight tingling sensation, which should dissipate within a few minutes.
Acne: Blackheads, Whiteheads
Aging Skin: Fine Lines and Wrinkles, Loss of Firmness
Application Area: Face
Ideal for these Concerns: Acne, Free Radical Damage, Hyperpigmentation, Redness
Ingredient: Herbal Extracts, Salicylic Acid
Preferences: Clean, Dermatologist Approved, Paraben-Free, Phthalate-Free, Sulfate-Free
Skin Care: Skin Care Treatments
Skin Care Treatments: Face Serums
Skin Type: Acne-Prone Skin, Combination Skin, Mature Skin, Oily Skin
Water/Aqua/Eau, Glycerin, Butylene Glycol, Alcohol Denat., Saccharum Officinarum (Sugarcane) Extract [Extrait de canne à sucre], Vaccinium Myrtillus Fruit/Leaf Extract, Triethanolamine, Salix Alba (Willow) Bark Extract, Glyceryl Polyacrylate, Arbutin, Polyporus Umbellatus (Mushroom) Extract, Menthol, Phenoxyethanol
Frequently Bought Together



Total Price: $300.00
Add both to cart
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
Reward members earn 50 points for every review written on verified purchases.
Best serum
I love this serum so much! It keeps my acne-prone skin clear and bright. Highly recommend!
Report this reviewGame Changer
This product deserves all the stars! The only thing I found that's helping to improve my skin
Report this reviewHoly Grail Serum
This is hands down my favorite serum. I use it daily and usually only need to buy 2-3 bottles a year. It has significantly helped improve my skin tone and texture and is absolutely a staple in my daily skincare routine. I will be a lifelong customer for sure! I have noticed the price of it go up quite a bit over the years which is unfortunate as it is already the most expensive product in my skincare inventory.
Report this reviewnot for me
Sadly, this product made my skin break out in rashes, I do have somewhat sensitive skin but I thought I'd give it a try since this line's other products work well for me! Unfortunately it just wasn't suited for my skin, maybe its the brightening agents?? oh well
Report this reviewGentle yet effective
I've been using this product whenever my face gets a congested spot (usually lower cheeks and above eyebrows) for 8 months now and I love it. I have sensitive skin, so I don't use harsh products. This serum feels good on my skin, does not burn, and does not irritate my rosacea. A couple drops is all you need to clear up a patch of acne. I believe my skin tone has improved as well. This product is on auto-ship bc I never want to run out.
Report this reviewso far so good
i am enjoying it haven’t seen much changes as i have been using it for a few weeks now
Report this reviewdifferent bottle
The first bottle of iS Clinical Active Serum was great and noticed a difference with acne. So I bought 2 more (one for my daughter and one for me). It was burning my skin to the point I was itching all over. My daughter said her new bottle was doing the same to her. What a waste of money.....clearly not the same product as the first one we purchased.
Report this reviewSkin Changer!
This serum changed my skin! It has given me a glow and I look forward to the tingling sensation because I know it is doing wonders for my skin!
Report this reviewAmazing - Can not live without!
I’ve lost count of how many bottles I’ve purchased because I simply can’t live without this serum. The first time I ran out I immediately noticed the difference in the texture and overall appearance of my skin. This serum also helps with acne and dullness of my skin. It really is all around the perfect serum.
Report this reviewUnderwhelming
It tingles a lot due to the menthol. Haven't seen any improvement after using the product, however.
Report this review