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Osmosis +Beauty Calm - Gentle Retinal Serum (1 fl. oz.)
An anti-aging facial serum for dry, aging, and sensitive skin.
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4 installments of $21.25 with Klarna Learn more
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4 installments of $21.25 with afterpay Learn more
Osmosis +MD Calm - Gentle Retinal Serum rebuilds your skin's outer dermis while reducing inflammation and hypersensitivity. Vitamin A conditions your complexion to encourage accelerated skin cell rejuvenation. Lactic acid resurfaces your natural barrier to soften the skin's overall texture. As a result, your complexion appears balanced and more youthful.
Key Ingredients:
- Vitamin A: encourages skin cell regeneration
- Lactic Acid: sloughs away dead skin
Key Benefits:
- Exfoliates
- Rejuvenates
- Enhances radiance
Due to a manufacturer packaging change, item received may vary from product image.
On clean skin, apply 1-2 pumps morning and/or evening. Spritz Boost or hydrate Mist and gently massage into skin. Follow with additional serum(s) and moisturizer if needed.
Application Area: Face
Ideal for these Concerns: Hyperpigmentation, Rosacea, Scars
Ingredient: Honey, Lactic Acid, Panthenol, Peptides, Retinol
Preferences: Certified Cruelty-Free, Clean, Vegan
Skin Care: Skin Care Treatments
Skin Care Treatments: Face Serums
Skin Type: Acne-Prone Skin, Normal Skin, Sensitive Skin
Water (Aqua), Glycerin, Phosphatidylcholine, Pentylene Glycol, Asiaticoside, Epilobium Angustifolium Flower/Leaf/Stem Extract, Hippophae Rhamnoides (Sea Buckthorn) Extract, Chlorella Vulgaris Extract, Palmitoyl Tripeptide-38, Chrysanthemum Parthenium (Feverfew) Extract, Niacinamide, Dimethyl Sulfone, Lactic Acid, Panthenol, Pyridoxine HCl, Fulvic Acid, Prunus Serotina (Wild Cherry) Bark Extract, Retinal*, Hydroxyproline, Beta-Glucan, Rubus Chamaemorus (Cloud Berry) Seed Oil, Cinnamomum Camphora (Camphor) Bark Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Rosa Damascena Flower Oil, Lonicera Caprifolium (Honeysuckle ) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Hydroxypropyl Cyclodextrin, Cyclodextrin, Alcohol, Xanthan Gum, Sodium Hydroxide, Benzyl Alcohol, Potassium Sorbate.
*0.0375% Retinaldehyde.
- Osmosis +MD
- Osmosis +Beauty
Frequently Bought Together



Total Price: $143.00
Add both to cart
Osmosis +Beauty Calm - Gentle Retinal Serum (1 fl. oz.)
An anti-aging facial serum for dry, aging, and sensitive skin.
Earn 425 reward points when purchasing this product as a rewards member*
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Free delivery after your first order
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You control the frequency
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No commitment. Cancel or delay
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Payment will be taken every month. months.
$85.00

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In stock
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4 installments of $21.25 with Klarna Learn more
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4 installments of $21.25 with afterpay Learn more
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Osmosis +MD Calm - Gentle Retinal Serum rebuilds your skin's outer dermis while reducing inflammation and hypersensitivity. Vitamin A conditions your complexion to encourage accelerated skin cell rejuvenation. Lactic acid resurfaces your natural barrier to soften the skin's overall texture. As a result, your complexion appears balanced and more youthful.
Key Ingredients:
- Vitamin A: encourages skin cell regeneration
- Lactic Acid: sloughs away dead skin
Key Benefits:
- Exfoliates
- Rejuvenates
- Enhances radiance
Due to a manufacturer packaging change, item received may vary from product image.
On clean skin, apply 1-2 pumps morning and/or evening. Spritz Boost or hydrate Mist and gently massage into skin. Follow with additional serum(s) and moisturizer if needed.
Application Area: Face
Ideal for these Concerns: Hyperpigmentation, Rosacea, Scars
Ingredient: Honey, Lactic Acid, Panthenol, Peptides, Retinol
Preferences: Certified Cruelty-Free, Clean, Vegan
Skin Care: Skin Care Treatments
Skin Care Treatments: Face Serums
Skin Type: Acne-Prone Skin, Normal Skin, Sensitive Skin
Water (Aqua), Glycerin, Phosphatidylcholine, Pentylene Glycol, Asiaticoside, Epilobium Angustifolium Flower/Leaf/Stem Extract, Hippophae Rhamnoides (Sea Buckthorn) Extract, Chlorella Vulgaris Extract, Palmitoyl Tripeptide-38, Chrysanthemum Parthenium (Feverfew) Extract, Niacinamide, Dimethyl Sulfone, Lactic Acid, Panthenol, Pyridoxine HCl, Fulvic Acid, Prunus Serotina (Wild Cherry) Bark Extract, Retinal*, Hydroxyproline, Beta-Glucan, Rubus Chamaemorus (Cloud Berry) Seed Oil, Cinnamomum Camphora (Camphor) Bark Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Rosa Damascena Flower Oil, Lonicera Caprifolium (Honeysuckle ) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Hydroxypropyl Cyclodextrin, Cyclodextrin, Alcohol, Xanthan Gum, Sodium Hydroxide, Benzyl Alcohol, Potassium Sorbate.
*0.0375% Retinaldehyde.
- Osmosis +MD
- Osmosis +Beauty
Frequently Bought Together



Total Price: $143.00
Add both to cart
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
Reward members earn 50 points for every review written on verified purchases.
Was Expecting Better
This product was disappointing. For the price I was expecting a lot more. It did not help with my redness and after 4 months of daily use I didn't really notice much difference in my skin. It also doesn't layer very well. I won't be buying again.
Report this reviewCalms inflamed acne
This calming serum paired with the rescue serum has calmed down the redness in my acne and has also help clear my acne.
Report this reviewGreat for sensitive skin.
I have Rosacea and this Retinol is the Best for sensitive skin.Keeps the wrinkles away.
Report this reviewLove!
Love this gentle retinol product. It’s the first retinol I’ve used that isn’t too harsh for my sensitive skin. And the results are amazing. My skin is looking very refined, with smaller pores and no redness. I’ve been using it for a month and can’t wait to see long-term results.
Report this reviewGreat gentle retinal!
This product line was recommended to me by my esthetician. I was initially very weary about trying a new serum! I had a pretty rough case of perioral dermatitis last year and have since been VERY cautious with what I apply on my face. I have had absolutely zero issues with this serum and noticed dramatic results after just my first bottle! It helps with any skin inflammation and has completely transformed my tone and texture. My skin looks so much smoother and radiant! I use this at night after my cleanser. I leave my face slightly damp and one pump applies nicely to both my face and neck. It feels a little sticky but absorbs quickly. Definitely recommend if you’re looking for a gentle retinal!
Report this reviewThis stuff is the bomb!
I have been using this for 5 months and it’s the bomb. My face is so super smooth. No breakouts and less rosacea!!!
Report this reviewBest gentle retin-a
Went through two bottles of this stuff before moving to the next level. It is so gentle, non drying and I saw a real difference in skin texture and pigmentation. Definitely recommend!
Report this reviewBlown Away
I'm blown away by this serum. I've tried everything under the sun for my acne and by far the most significant changes I've seen in my skin is from osmosis products. Calm has helped my acne by decreasing the amount of breakouts and decreasing the healing time. I have been using it with stemfactor too.
Report this reviewThe best skin find....ever!
I have struggled with acne for most of my adult life. It only intensified after babies, hormone fluctuations, stress, etc. I started using this product last year and it has completely changed my skin! It has evened out my skin tone, refined my pores, minimized my breakouts, and helped my combo skin never get too oily or too dry. Literally, this product is my everything! Highly recommend.
Report this reviewReally Enjoy This
I started using this a few weeks ago and I really enjoy this product. I had not been using retinal before but started using this every other day. I know you are supposed to ease into it but I figured if my skin peeled while I was staying at home during this time it wouldn't bother me. My skin has not peeled, I have some slight discomfort but again that is due to me jumping right into using this. I really enjoy that it has lactic acid. The directions say use 1-2 pumps but I don't need to use a full pump to cover my entire face. I see why people would say they would run out of this product quickly if they were using that much but I think it would be very hard to apply all of that product to your face.
Report this review