Earn 2x points on SkinMedica | TWO Free Gifts when you spend $200+ on your purchase. SHOP NOW
FREE US Shipping $50+ Auto-Replenishment 15% off first App Order Dermstore Rewards
iS Clinical

iS Clinical Active Serum (1 oz.)

A multi-tasking face serum that improves the appearance of aging, acne-prone and dull complexions.

Rewards members earn 740 points on this order. Register & opt in at checkout.

Join Dermstore Rewards

$148.00

Or 4 interest free payments of $37.00 with


In stock | Usually dispatched within 24 hours


Delivery & Returns
Free delivery is available on all orders over $50. Please see our shipping information page for all available delivery options.
If I'm not completely happy with my item?
Please see our returns policy.
*points earned on final checkout price, after any applied discounts.

Frequently Bought Together

iS Clinical Active Serum (1 oz.)

This item

iS Clinical Active Serum (1 oz.)

$148.00

Total Price:

$240.00

Other Customers Bought

Customer Reviews

4.63 stars out of a maximum of 5

5 stars rating 416 reviews

4 stars rating 46 reviews

3 stars rating 31 reviews

2 stars rating 11 reviews

1 stars rating 12 reviews

Top Customer Reviews

Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

I like this a lot and was recommended by my dermatolgist

4 stars out of a maximum of 5

I have rosecea and asked my dermatologist for a serum I can use to fight wrinkles that won't upset the redness in my cheeks. So far so good with this product.

by Anonymous Verified Purchase

Was this helpful?

Great for acne-prone skin!

5 stars out of a maximum of 5

I have been using iS clinical since the summer of 2010. I am prone to breakouts and I have large pores and semi-oily skin. This product really minimizes my breakouts; I only get 2-4 pimples per month, whereas before I would have breakouts regularly. I feel like my skin has "regulated" and it no longer goes through extremely dry periods followed by extremely oily periods, which is the problem I had with other products. This is an investment for sure, but worth it for me!

by Anonymous Verified Purchase

Was this helpful?

potent serum

5 stars out of a maximum of 5

This was recommended by my dermatologist with the eye cream. I am very satisfied with the results after couple weeks of use.

by Anonymous Verified Purchase

Was this helpful?

good for break out

5 stars out of a maximum of 5

helps to reduce the irritated looking appearance of skin breaking out. it also helps with the dryness and texture of the skin.

by David Verified Purchase

Was this helpful?

Smooth, clear skin!

5 stars out of a maximum of 5

I love this serum! It is fairly mild on my skin. No irritation, yet is is really doing a wonderful job of clearing and smoothing out my skin. Would recommend it!

by Anonymous Verified Purchase

Was this helpful?

Keeps your skin smooth

4 stars out of a maximum of 5

The product is great at smoothing skin, keeping blackheads to a minimum and is not drying. Recommend highly. Cost can be prohibitive.

by Anonymous Verified Purchase

Was this helpful?