Earn 2x points on SkinMedica | TWO Free Gifts when you spend $200+ on your purchase. SHOP NOW
FREE US Shipping $50+ Auto-Replenishment 15% off first App Order Dermstore Rewards
iS Clinical

iS Clinical Hydra-Cool Serum (1 oz.)

A multi-use formula to restore hydration and provide excellent antioxidant protection.

Rewards members earn 515 points on this order. Register & opt in at checkout.

Join Dermstore Rewards

$103.00

Or 4 interest free payments of $25.75 with


In stock | Usually dispatched within 24 hours


Delivery & Returns
Free delivery is available on all orders over $50. Please see our shipping information page for all available delivery options.
If I'm not completely happy with my item?
Please see our returns policy.
*points earned on final checkout price, after any applied discounts.

Frequently Bought Together

iS Clinical Hydra-Cool Serum (1 oz.)

This item

iS Clinical Hydra-Cool Serum (1 oz.)

$103.00

Total Price:

$170.00

Other Customers Bought

Customer Reviews

4.65 stars out of a maximum of 5

5 stars rating 115 reviews

4 stars rating 22 reviews

3 stars rating 6 reviews

2 stars rating 2 reviews

1 stars rating 3 reviews

Top Customer Reviews

Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

Real Results

5 stars out of a maximum of 5

I basically only use iS Clinical products, I love the active serum, the pro-heal serum advance plus and the moisture complex. I some times purchase the Hydra-Cool Serum and this last go around of purchasing I saw results after only a few applications.

by Anonymous

Was this helpful?

This stuff is So good

5 stars out of a maximum of 5

Goes on so smooth and absorbs quickly. Not tacky, instant hydrating feeling. By far my favorite serum type product I've used. Can't say enough good things

by Anonymous Verified Purchase

Was this helpful?

Moisturizes well

4 stars out of a maximum of 5

This Serum Moisturizes well, but I prefer the Active Serum. A strange feeling on the skin.

by Vicki

Was this helpful?

interesting texture

5 stars out of a maximum of 5

This hydration serum has a pretty interesting texture. It appears to be liquid-ish but actually feels a little slimy. However, it absorbs into the skin real quick, like a second, so you have to rub it in real fast as well. One pump is definitely enough for my entire face. It plumps my skin and makes it tighter and well moisturized. But the price is too steep for a hydration serum.

by Anonymous

Was this helpful?

Smoothing and cooling

5 stars out of a maximum of 5

This product goes on so nicely and is non-sticky. It has a cooling effect and feels amazing for those of us with redness in the skin. Hydrating all day and makes skin soft.

by Anonymous

Was this helpful?

I love this stuff

5 stars out of a maximum of 5

Honestly, when a dermatologist suggested I use this in conjunction with the IS Recovery Balm I thought it was a little over the top. But it really makes all the difference. I love this stuff. When I do not use it, my moisturizer is not properly absorbed by my skin. It is pricey, but when I think about how much more moisturizer I would have to use to get the same effect, it makes total sense. I use this before my moisturizer both day and night. It keeps my skin supple and allows for more smooth make up application.

by Anonymous Verified Purchase

Was this helpful?

VERY HYDRATING SERUM

5 stars out of a maximum of 5

I ordered this serum because of all the rave reviews on the isClinical brand. And this product definitely does not disappoint. My skin is very dry and sensitive and can sometimes burn depending on what other serum is use for acne or dark spots. When i put this serum on it has cooling effect and hydrates the skin very deeply. I use this in my morning and nighttime skincare routine. AMAZING PRODUCT

by Vanessa Verified Purchase

Was this helpful?

Love this product

5 stars out of a maximum of 5

This serum goes on smoothly and makes my skin feel amazing. No additional moisturizer needed when I use this.

by Anonymous Verified Purchase

Was this helpful?

My go to night serum!

5 stars out of a maximum of 5

This has been a long standing product used in my daily regimen. Helps to calm irritation and redness caused by my eczema while also preventing signs of aging.

by Ryan Verified Purchase

Was this helpful?

Great Serum!

5 stars out of a maximum of 5

I am 49 years old have combination, acne prone skin, and I love the way this serum hydrates my skin without feeling too heavy. It really helps balance the acne products I use. The cooling feeling is very refreshing!

by Anonymous Verified Purchase

Was this helpful?