UP TO 40% OFF + EXTRA 10% OFF SALE ITEMS WITH CODE: EXTRA10
FREE US Shipping $50+ Auto-Replenishment 15% off First App Order Dermstore Rewards
SkinMedica

SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)

A retinol-based, night lotion for first-time users of all skin types.

Rewards members earn 320 points on this order. Register & opt in at checkout.

Join Dermstore Rewards

$64.00

Or 4 interest free payments of $16.00 with


In stock | Usually dispatched within 24 hours

Image 1 - Three silver bottles of SkinMedica Retinol Complex product are shown with text Retinol Complex A Skincare Essential, Diminishes the appearance of sun damage fine lines and coarse wrinkles, Enhances skin tone texture and resiliency, Renews skin, 0.25, 0.5, and 1.0. Image 2 - A split image shows a womans face before and after treatment, with the left side showing redness and uneven tone and the right side showing improved tone and texture, with the text Before After BASELINE AFTER 12 WEEKS* 54 YEAR OLD FEMALE. UNRETOUCHED PHOTOS OF SUBJECT AT BASELINE AND 12 WEEKS AFTER USING RETINOL COMPLEX 0.25. *DATA ON FILE AT SKINMEDICA. Image 3 - A white cream texture is shown against a light brown background with the text Features PhytoShield™ Complex that encapsulates retinol for targeted delivery Helps to minimize the irritation typically associated with the use of retinol. Image 4 - Three silver pump bottles of SkinMedica Retinol Complex in strengths 1.0, 0.5, and 0.25 with text that says Pick Your Strength Suitable for all skin types and available in 3 strength levels If you are new to retinol, its recommended to begin with 0.25, then progress to 0.5 and 1.0. Image 5 - A hand holds a SkinMedica Retinol Complex 1.0 bottle next to text explaining how to use the product which reads How to Use WHEN TO APPLY In the evening after cleansing and toning, and before your moisturizer If you are new to retinol, begin twice a week, gradually increasing to each evening or as tolerated WHERE TO APPLY To your entire face, avoiding eyes Mild redness, peeling and irritation are expected when using this product. Use a daily sun protection with SPF 30 or higher and limit sun exposure while using this product, and for a week following discontinuation. The bottle text reads SkinMedica RETINOL COMPLEX 1.0 1 fl oz / 29.6 ml. Image 6 - An image displaying text explaining the benefits of glass packaging next to a product bottle with the text The Benefits of Glass Packaging Protection from Light Retinol is sensitive to light which can reduce its effectiveness Glass bottles protect from exposure to light Chemical Stability Glass minimizes potential chemical interactions between retinol and the packaging maintaining its stability and efficacy Preservation of Ingredients Glass better preserves active ingredients maintaining the retinols quality and extending its shelf life SkinMedica RETINOL COMPLEX 1.0 1 FL. OZ. / 29.6 mL. Image 7 - Image showing SkinMedica skincare products with the title Complete Your SkinMedica Method Routine followed by five steps 01 The Cleanse Factor AHA BHA Exfoliating Cleanser 02 The Growth Factor TNS Advanced+ Serum 03 The Correct Factor Retinol Complex 04 The Hydrate Factor HAS Hydra Collagen Replenish + Restore Hydrator 05 The Protect Factor Essential Defense Mineral Shield Broad Spectrum SPF 35 Sunscreen. Image 8 - A close-up of a smiling womans face with text overlay that reads Pioneer of regenerative skincare With over 25 years of innovation, SkinMedica develops professional-grade products for every step in a complete skincare routine.

Delivery & Returns
Free delivery is available on all orders over $50. Please see our shipping information page for all available delivery options.
If I'm not completely happy with my item?
Please see our returns policy.
*points earned on final checkout price, after any applied discounts.

Frequently Bought Together

SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)

This item

SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)

$64.00

Total Price:

$144.00

Other Customers Bought

Customer Reviews

4.79 stars out of a maximum of 5

5 stars rating 235 reviews

4 stars rating 29 reviews

3 stars rating 4 reviews

2 stars rating 3 reviews

1 stars rating 3 reviews

Top Customer Reviews

Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

Retinol .25

5 stars out of a maximum of 5

Great product for fine lines and making skin smooth and soft

by Kathleen Verified Purchase

Was this helpful?

Effective

5 stars out of a maximum of 5

I bought this retinol per a friend's recommendation. I have rosacea, so my skin is sensitive, however this one has not caused any problems and I have been able to tolerate. Planning on continuing using it. Recommend it

by Sinay Verified Purchase

Was this helpful?

Perfect for Sensitive Skin

5 stars out of a maximum of 5

If you want to be able to use retinol and not take a month off due to extreme irritation, this is it. The formula is so perfect for us sensi's.

by Anna, RN

Was this helpful?

Best retinol for sensitive, dry and acne prone skin

5 stars out of a maximum of 5

Started slow with once or twice a week and over the course of 6 months built to 4-5 days a week. I did not have dry patches, unless I did 2 nights in a row during Chicago winter, which is incredible.  My hormonal acne is gone and my skin is smoother and I can wear makeup without it clinging to 5 dry patches. Life changing! I use hydralonic acid and moisturizer with it for hydration. 

by Ashley Verified Purchase

Was this helpful?

Best Retinol

5 stars out of a maximum of 5

My skin appears smoother and brighter after using this retinol. The 0.25 concentration is gentle for around my eyes.

by Val Verified Purchase

Was this helpful?

beginner friendly

5 stars out of a maximum of 5

This retinol is formulated so well. It’s lightweight, absorbs well and no irritation! 

by Elisabeth Verified Purchase

Was this helpful?

Good on sensitive skin

5 stars out of a maximum of 5

I’ve tried different retinol brands, but this is my favorite. It goes on smoothly and is well absorbed by my dry/psoriasis patchy skin. I feel like it even improves those patches. This one is a keeper. 

by Michelle Verified Purchase

Was this helpful?

Excellent addition to skincare routine

5 stars out of a maximum of 5

This is my first time incorporating retinol into my skincare routine so I took the advice I've seen out there about starting with a low concentration which is why I chose the .25 I was skeptical at first about whether I would actually see any sort of results with such a low concentration, but I eased into it by only using it a couple of times a week at first and gradually working up to daily usage at night. The results are subtle, but after a month of usage, I have already noticed an improvement in my skin texture and overall complexion. At no point did I experience excessive dryness or suffer from any adverse side effects. I do make sure to follow it up with a thick moisturizer every night to prevent any dryness and during the day I always put on two layers of sunscreen. Every day I wake up with my skin feeling incredibly soft and glowy and I have noticed that my acne breakouts have reduced significantly. I am super pleased with this product.

by Amadine Verified Purchase

Was this helpful?

Great

5 stars out of a maximum of 5

This product is great for a retinol starting out!

by Calyn Verified Purchase

Was this helpful?

Love so far

5 stars out of a maximum of 5

Loving so far. Simple, straightforward instructions for beginning retinol users. Great for first time users!!!

by K Verified Purchase

Was this helpful?