SkinMedica TNS Advanced+ Serum (1 fl. oz.)
Rewards members earn 2950 points on this order. Register & opt in at checkout.
$295.00
Or 4 interest free payments of $73.75 with
Auto-Replenishment
- ✓ 20% off initial purchase and 20% savings on future replenishment orders
- ✓ Free delivery after your first order
- ✓ You control the frequency
- ✓ No commitment. Cancel or delay
In stock | Usually dispatched within 24 hours

SkinMedica's TNS Advanced+ Serum is a skin rejuvenating formula that visibly improves the appearance of coarse wrinkles, fine lines and sagging skin. Powered by TNS®-MR and Renessensce (RSC) Advanced, this combination encourages skin cell renewal and supports collagen and elastin levels revealing a smoother, more radiant and youthful complexion.
Key Ingredients:
- TNS®-MR: This advanced formula acts on multiple levels to help get you to your best results. Next-generation growth factor blend supports healthy skin functions and an innovative peptide complex nourishes your skin.
- Renessensce (RSC) Advanced: This highly active blend of botanicals, marine extracts, and peptides includes french flax seed to support repair functions. Spanish marine extract supports skin’s renewal processes and green microalgae support collagen and elastin levels.
Key Benefits:
- Smooths visible coarse wrinkles and fine lines
- Visibly lifts sagging skin
- Evens the appearance of skin tone and texture
- Visible results start in just 2 weeks, with progressive improvements measured over 24 weeks*
- Colorless and fragrance-free
*Results from a clinical study with 45 male and female subjects, ages 37—70, that received TNS® Advanced+ Serum twice daily for 24 weeks.
AM/PM: Dispense a single pump onto the back of your hand, blend together and apply to the face morning and night. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
Aging Skin: Fine Lines and Wrinkles, Loss of Firmness
Application Area: Face
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Holiday: Gifts for Mom
Preferences: Fragrance-Free
Skin Care: Skin Care Treatments
Skin Care Treatments: Face Serums
Skin Type: Mature Skin, Normal Skin
Water/Aqua/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Trifluoroacetyl Tripeptide-2, Dimer Tripeptide-43, Hydrolyzed Linseed Extract, Vitis Vinifera (Grape) Flower Cell Extract, Pyrus Malus (Apple) Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Dextran, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
For the latest information, it is recommended to review the ingredient list printed on the packaging of the product prior to usage or consumption.
- SkinMedica
- 1oz
Frequently Bought Together

This item
SkinMedica TNS Advanced+ Serum (1 fl. oz.)
$295.00
Other Customers Bought
Customer Reviews
5 stars rating 441 reviews
4 stars rating 82 reviews
3 stars rating 32 reviews
2 stars rating 12 reviews
1 stars rating 19 reviews
Top Customer Reviews
Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.
Fountain of Youth
I take VERY good care of my skin and this serum is my one MUST have in my arsenal. Over time, my skin has become less sensitive, more vibrant and time has stood still. I do like this formula even more than the original formulation. It is light and easily absorbed yet provides enough moisture that I really don’t need a moisturizer during the Summer. After applying my retinol, I apply this magic serum and my skin elasticity has remained healthy and only improved over my years of consistent use. (I used the original formula and switched to this new one as soon as it was released). I also love that the ingredients are dispersed from separate openings to mix immediately at the time of use to harness all of the potential benefits of the ingredients. If cost is an issue for you, I would go with a good no expensive cleanser and retinol and save my money for this amazing serum of youth in a bottle.
by DrGGM Verified Purchase
Was this helpful?
TNS First Timer
This was the first time I tried TNS Advanced Serum and I love it! I have used the TNS Recovery Complex and that is great too, but it leaves my skin feeling tight. This is very hydrating and makes your skin feel so soft. Will definitely repurchase.
by Erin Verified Purchase
Was this helpful?
Wonderful
I really like SkinMedic. I can’t always afford it but try to only use SkinMedica products
by Shirley Verified Purchase
Was this helpful?
Great product
This serum is the new version of the Essential Serum. I like both products, but this one is a little lighter weight so it goes on nicely under makeup. Occasionally the pump has issues and only one of the two products comes out. There is a hole on the bottom and if you stick a paperclip in it, it sometimes it will unstop it.
by Rob
Was this helpful?
Wow! this really works
My dermatologist recommended this product to help with my loss of collagen on my face. You need to take a picture of yourself (before using this) and after a month compare...you will see a difference.
by ND Verified Purchase
Was this helpful?
Seems to keep skin more hydrated
I was not sure if I was seeing any results until I ran out. Then I realized that this growth serum was helping to keep my skin more hydrated possibly by locking in moisture. I was only using the serum once a day in the morning as I use retinol at night and did not want to mix the two. I will keep using this. I gave it 4 stars due to the price of the product
by Celeste Verified Purchase
Was this helpful?
Magic
I didn't want to like this because it is so pricey but it works great. It is really fun to use and I enjoy putting it on. I like it a lot.
by Sophie
Was this helpful?
Expensive but worth it
The serum is fantastic! My derm recommended it as a post-procedure regimen, and I never stopped using it. The skin looks plump, hydrated when I use it. Unfortunately, the effect wears off after a couple of days of not using it. It is expansive, considering it will only last you a month with a twice a day application.
by Yulia Verified Purchase
Was this helpful?
Good for skin but no miracles for wrinkles
Tried two bottles on my mid-60s skin over 3 months hoping for a bit of dimishment in lines and wrinkles. The serum conditioned my skin well, did nothing for wrinkles or fine lines, and pilled under the SkinMedica sunscreen. For me, it’s a no. Still using other products in this line.
by Mary
Was this helpful?
Glorious Glowing Skin!
This velvety serum is absorbed immediately, a tiny bit goes a very long way. Expensive, and well worth it to me. My face is refreshed, soothed, smooth textured, glowing. I have used many facial serums, never ever had such a distinct difference in my skin tone and texture. Recommended by my Plastic Surgeon, I am delighted with results.
by Erma Verified Purchase
Was this helpful?