Earn 2x points on SkinMedica | TWO Free Gifts when you spend $200+ on your purchase. SHOP NOW
FREE US Shipping $50+ Auto-Replenishment 15% off first App Order Dermstore Rewards
SkinMedica

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

A powerful anti-aging serum that targets fine lines, deep wrinkles and sagging skin.

Rewards members earn 2950 points on this order. Register & opt in at checkout.

Join Dermstore Rewards

$295.00

Or 4 interest free payments of $73.75 with


In stock | Usually dispatched within 24 hours

Image 1 - Image of a skin serum bottle labeled TNS® ADVANCED+ SERUM with a background of glass beakers, featuring the text Next Generation Skin Rejuvenation and additional claims such as Clinically proven to address sagging skin, Smooths visible coarse wrinkles and fine lines, and Results start in just 2 weeks*.
Image 2 - Image showing a side-by-side comparison of a 60-year-old females face before and after using TNS Advanced+ serum, with the Before image on the left showing visible wrinkles and the After image on the right indicating smoother skin with marked improvements at week 2, alongside text detailing baseline and improvements.
Image 3 - Image shows a cream or gel texture with text highlighting key ingredients for skincare. Visible text includes: Key Ingredients TNS-MR An advanced formula to help you get age-defying results with: + NEXT-GENERATION GROWTH FACTOR BLEND Supports healthy skin functions + INNOVATIVE PEPTIDE COMPLEX Nourishes your skin Renessence (RSC) Advanced Specifically designed to support the results of the growth factor blend and includes: + MARINE EXTRACT Supports skin’s renewal process + GREEN MICROALGAE Supports collagen and elastin levels.
Image 4 - A sleek bottle of SkinMedica TNS Advanced+ Serum is displayed next to a small amount of the serum on a light background, with the text stating that in a clinical study, after 12 weeks, patients using the serum felt they looked up to 6 years younger.
Image 5 - A pair of hands holds a cosmetic bottle with instructions on its use, including details on when and how to apply the product, and visible text that reads: How to Use, WHEN TO APPLY, In the morning and evening after cleansing and toning, HOW TO APPLY, Before applying, invert and tap the bottom of the bottle, Remove the cap and press on the center of the pump to dispense onto the back of your hand using a bunny finger application, Blend the product together before applying, Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with warm water.
Image 6 - Image of SkinMedica products arranged on a light background, including an AHA/BHA Exfoliating Cleanser, TNS Advanced+ Serum, Instant Bright Eye Cream, HA⁵ Hydra Collagen Replenish + Restore Hydrator, and Essential Defense Mineral Shield Broad Spectrum SPF 35 Sunscreen, with the text Complete Your SkinMedica Method Routine above them.

Delivery & Returns
Free delivery is available on all orders over $50. Please see our shipping information page for all available delivery options.
If I'm not completely happy with my item?
Please see our returns policy.
*points earned on final checkout price, after any applied discounts.

Frequently Bought Together

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

This item

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

$295.00

Total Price:

$479.00

Other Customers Bought

Customer Reviews

4.55 stars out of a maximum of 5

5 stars rating 441 reviews

4 stars rating 82 reviews

3 stars rating 32 reviews

2 stars rating 12 reviews

1 stars rating 20 reviews

Top Customer Reviews

Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

Good not Great

4 stars out of a maximum of 5

I know this product has a ton of great reviews, and it's a great product, but I will say it caused alot of skin irritation for me. All of the TNS products did. I have super sensitive and reactive skin, so that could be why... but if that's you just beware on this one!

by Anonymous

Was this helpful?

A+++ Serum

5 stars out of a maximum of 5

This serum is the gold standard! Such great results! My esthetician recommended also!

by Kayla Verified Purchase

Was this helpful?

Pricey but results

5 stars out of a maximum of 5

Gosh, it is very expensive. I will say I did see results very quickly though. Evened out skin tone, less visible wrinkles, reduced redness and a nice glow.

by Anonymous

Was this helpful?

Skinmedica

5 stars out of a maximum of 5

This is the best brand i've used. I like using this product and its fragrance free. Quick results and makes my skin so smooth. A must try for the face.

by Anonymous

Was this helpful?

Worth It!

5 stars out of a maximum of 5

I didn't want to love this product, its expensive but it works! After I ran out of my first bottle I thought I would not buy again, but the difference on my skin was noticeable, I missed how healthy it looked while I was using the serum. After regular use my skin feels more hydrated, glow and dewy, this is a must!

by Anonymous Verified Purchase

Was this helpful?

Jury is still out

3 stars out of a maximum of 5

This is the first time I used this product, I usually use the other TNS growth factor serum. They seem the same, maybe I needed to use more than 1 bottle. I bought this on sale to try it. I think I will stick with the other TNS growth factor serum and save a few bucks..

by Heather Verified Purchase

Was this helpful?

*PRO TIP* A solution to dispenser woes

5 stars out of a maximum of 5

It boggles the mind that such an expensive a product would have so ineffective a dispensing mechanism. With that said, I found a solution to the uneven dispensing problem and felt compelled to share it with those who haven't thought of it already. STORE THE PRODUCT UPSIDE DOWN WHEN NOT IN USE! Gravity ensures that both serums flow to the "top" of either pump, thus ensuring they are pumped out in equal measures. Trust me, it works.

by Anonymous

Was this helpful?

Too soon to tell

4 stars out of a maximum of 5

I have been using this serum for 3 weeks and don't see a significant difference in my skin yet. I am hoping with continued use I will see some results. I'm hoping to see the area under my chin and neck improve. I wish the despenser was not a pump so I can get out every last drop since it is so expensive. I will try to give an updated review after using the product longer. I'm not sure how long one container will last. I am hoping it lasts several months.

by Kimberly Verified Purchase

Was this helpful?

Best product I've used

5 stars out of a maximum of 5

I'm always hesitant to try new skincare products because they are expensive and I have sensitive skin. I've been using this product for about 2 months. Usually in the winter my skin becomes dry, red with rough patches. After using this product my skin feels softer and looks more vibrant. We shall see if my wrinkles improve but so far I am very happy.

by Anonymous Verified Purchase

Was this helpful?

Holy Grail!

5 stars out of a maximum of 5

I love this- such an improvement on the other TNS serum, especially the scent! Left my skin with great texture- pricey but worth it.

by Anonymous Verified Purchase

Was this helpful?