SkinMedica TNS Advanced+ Serum (1 fl. oz.)
Rewards members earn 2950 points on this order. Register & opt in at checkout.
$295.00
Or 4 interest free payments of $73.75 with
Auto-Replenishment
- ✓ 20% off initial purchase and 20% savings on future replenishment orders
- ✓ Free delivery after your first order
- ✓ You control the frequency
- ✓ No commitment. Cancel or delay
In stock | Usually dispatched within 24 hours

SkinMedica's TNS Advanced+ Serum is a skin rejuvenating formula that visibly improves the appearance of coarse wrinkles, fine lines and sagging skin. Powered by TNS®-MR and Renessensce (RSC) Advanced, this combination encourages skin cell renewal and supports collagen and elastin levels revealing a smoother, more radiant and youthful complexion.
Key Ingredients:
- TNS®-MR: This advanced formula acts on multiple levels to help get you to your best results. Next-generation growth factor blend supports healthy skin functions and an innovative peptide complex nourishes your skin.
- Renessensce (RSC) Advanced: This highly active blend of botanicals, marine extracts, and peptides includes french flax seed to support repair functions. Spanish marine extract supports skin’s renewal processes and green microalgae support collagen and elastin levels.
Key Benefits:
- Smooths visible coarse wrinkles and fine lines
- Visibly lifts sagging skin
- Evens the appearance of skin tone and texture
- Visible results start in just 2 weeks, with progressive improvements measured over 24 weeks*
- Colorless and fragrance-free
*Results from a clinical study with 45 male and female subjects, ages 37—70, that received TNS® Advanced+ Serum twice daily for 24 weeks.
AM/PM: Dispense a single pump onto the back of your hand, blend together and apply to the face morning and night. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
Aging Skin: Fine Lines and Wrinkles, Loss of Firmness
Application Area: Face
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Holiday: Gifts for Mom
Preferences: Fragrance-Free
Skin Care: Skin Care Treatments
Skin Care Treatments: Face Serums
Skin Type: Mature Skin, Normal Skin
Water/Aqua/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Trifluoroacetyl Tripeptide-2, Dimer Tripeptide-43, Hydrolyzed Linseed Extract, Vitis Vinifera (Grape) Flower Cell Extract, Pyrus Malus (Apple) Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Dextran, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
For the latest information, it is recommended to review the ingredient list printed on the packaging of the product prior to usage or consumption.
- SkinMedica
- 1oz
Frequently Bought Together

This item
SkinMedica TNS Advanced+ Serum (1 fl. oz.)
$295.00
Other Customers Bought
Customer Reviews
5 stars rating 442 reviews
4 stars rating 82 reviews
3 stars rating 32 reviews
2 stars rating 12 reviews
1 stars rating 19 reviews
Top Customer Reviews
Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.
Advanced Serum review
I have been using this product for about a month now. I honestly haven't noticed much of a difference between this and the original TNS Serum other than it does not smell as weird. I do love the original though but will probably buy this one more time as I don't think I've been using it long enough to see the full results.
by Lora Verified Purchase
Was this helpful?
Dispenser issues!
Purchased my first bottle of Skinmedica TNS Advanced Serum at my doctor's office and had no problem with the dispenser but no so with the bottle I purchased here. It's hit or miss whether both sides will dispense the product. Neither side appears to be clogged up. Not happy at all!
by Anonymous Verified Purchase
Was this helpful?
TNS advanced Serum
Love the new TNS advanced serum!! Seeing changes in skin! Like the way it is lifting my skin and changes in sagging! Great product
by Anonymous Verified Purchase
Was this helpful?
Happy but no noticeable change
So I do like this product but I am on my third bottle and can't say it's eliminated any wrinkles I have. I use it nightly because when I use it in the morning too I felt like My skin was flaking when I applied make up on top of it. When I use the tns essential serum before make up I don't have the flaking. There is no smell which is a positive
by Anonymous Verified Purchase
Was this helpful?
Worth the Wait!
I read about this product 1 year ago as a BIG BREAKTHROUGH in the October issue of Allure BEST OF BEAUTY. I patiently waited 9 months for its release & purchased it as soon as possible (I even contacted SkinMedica several times). I LOVE it & previously used its predecessor TNS Serum. My friends have told me how terrific my skin looks & wondered if I had laser treatment! The dispenser is brilliant, but the funny thing is, that is probably my least favorite thing about the product~~you mix it on the back of your hand ( I understand why they did this, so I cannot really complain)! I definitely will continue using this product.
by Anonymous Verified Purchase
Was this helpful?
Excellent product
This is a great product. I have been using the previous version, but find this one is more "addictive". It feels wonderful and does make my skin look fresher and smoother. The downside is the cost relative to the volume of product. The large bottle contains only 1 oz of product and it goes fast - used twice a day it barely lasts a month.
by Anonymous Verified Purchase
Was this helpful?
MIRACLE WORKER
I went to a skin center and they chose this for me. BEST skin in 20 years!! Plump , smooth , makeup goes on like a dream!
by Anonymous Verified Purchase
Was this helpful?
New packaging same results
This is a great product now that it is missing the smell of the old version. The downside to this is the increase in price since it is "new". Overall it is a great product but you might want to skip this if you are younger.
by Anonymous
Was this helpful?
Fantastic Product but Horrible Dispenser Pump
For the price of this product, you'd think that the marketing people at skin medica would notice how the pump mechanism is the worst. On top of that, the packaging must cost a fortune which I'm sure adds to the outrages cost of the product. On the other had, it's a heck of a product.....I've used it for at least a year but I'm done until they improve the pump even more.......! Why the heck do you have to make such fancy packaging anyway.....you could bring the cost down a bit and still have a wonderful product.
by Jennifer Verified Purchase
Was this helpful?
New packaging
After applying and using the product. The texture and potency is even better than the original.
by Anonymous Verified Purchase
Was this helpful?