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Paula's Choice CLINICAL Niacinamide 20 Treatment (0.67 fl. oz.)
A highly concentrated serum that improves the skin's tone and texture.
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4 installments of $13.00 with Klarna Learn more
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4 installments of $13.00 with afterpay Learn more
Achieve a smoother and more radiant complexion with CLINICAL Niacinamide 20% Treatment from Paula's Choice. This advanced, concentrated serum helps to tighten and minimize the appearance of pores and rough bumps caused by age or sun damage. Niacinamide normalizes pore function and protects from further stretching when exposed to damaging UV light, resulting in improved radiance and texture.
Key Ingredients:
- 20% Niacinamide (Vitamin B3): minimizes enlarged pores, improves uneven skin tone and promotes a smooth, blemish-free complexion
- Acetyl Glucosamine: brightens skin tone and steadily refines skin texture
- Vitamin C: visibly improves the look of uneven skin tone and discoloration
- Green Tea: helps defend and repair skin damaged by UV light, airborne pollutants and other environmental aggressors
Key Benefits:
- Dramatically reduces the look of stretched pores
- Helps reduce hard clogged bumps and orange-peel texture
- Visibly improves blotchy tone and fades post-blemish marks
Apply a few drops once or twice daily after cleansing, toning and exfoliating. At night, layer with other treatment products as needed and follow with moisturizer; during the day, finish with a sunscreen rated SPF 30 or greater.
Acne: Acne Scars
Application Area: Face
Ingredient: Green Tea, Niacinamide
Preferences: Hypoallergenic, Oil-Free
Skin Care Treatments: Face Serums
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water (Aqua), Niacinamide, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra (Licorice) Root Extract, Spiraea Ulmaria (Meadowsweet) Extract, Portulaca Oleracea (Purslane) Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis (Green Tea) Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin.
- CLINICAL
- Paula's Choice
Frequently Bought Together



Total Price: $91.00
Add both to cart
Paula's Choice CLINICAL Niacinamide 20 Treatment (0.67 fl. oz.)
A highly concentrated serum that improves the skin's tone and texture.
Earn 260 reward points when purchasing this product as a rewards member*
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Free delivery after your first order
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You control the frequency
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No commitment. Cancel or delay
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Payment will be taken every month. months.
$52.00
In stock
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4 installments of $13.00 with Klarna Learn more
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4 installments of $13.00 with afterpay Learn more
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Achieve a smoother and more radiant complexion with CLINICAL Niacinamide 20% Treatment from Paula's Choice. This advanced, concentrated serum helps to tighten and minimize the appearance of pores and rough bumps caused by age or sun damage. Niacinamide normalizes pore function and protects from further stretching when exposed to damaging UV light, resulting in improved radiance and texture.
Key Ingredients:
- 20% Niacinamide (Vitamin B3): minimizes enlarged pores, improves uneven skin tone and promotes a smooth, blemish-free complexion
- Acetyl Glucosamine: brightens skin tone and steadily refines skin texture
- Vitamin C: visibly improves the look of uneven skin tone and discoloration
- Green Tea: helps defend and repair skin damaged by UV light, airborne pollutants and other environmental aggressors
Key Benefits:
- Dramatically reduces the look of stretched pores
- Helps reduce hard clogged bumps and orange-peel texture
- Visibly improves blotchy tone and fades post-blemish marks
Apply a few drops once or twice daily after cleansing, toning and exfoliating. At night, layer with other treatment products as needed and follow with moisturizer; during the day, finish with a sunscreen rated SPF 30 or greater.
Acne: Acne Scars
Application Area: Face
Ingredient: Green Tea, Niacinamide
Preferences: Hypoallergenic, Oil-Free
Skin Care Treatments: Face Serums
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water (Aqua), Niacinamide, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra (Licorice) Root Extract, Spiraea Ulmaria (Meadowsweet) Extract, Portulaca Oleracea (Purslane) Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis (Green Tea) Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin.
- CLINICAL
- Paula's Choice
Frequently Bought Together



Total Price: $91.00
Add both to cart
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
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Loved this product
I had been using a 10% niacinamide and wanted something stronger, and this did the trick! loved the way it applied!
Report this reviewMeh doesn’t work for melasma
Very unimpressive. I’ve been an esthetician for 21 years and I don’t get why people trust these products. I stopped using Lytera to try this and my pigment came back a little. Niacinimide should be medical grade or nothing will improve melasma
Report this reviewAbsolute fave!
This is an absolute must in my daily regimen! I had dry, discolored skin from acne and melasma from pregnancy my skin was awful. It goes on and absorbs great and it’s made a huge difference in my skin using it consistently.
Report this reviewNice Niacinamide
Bought this at the recommendation of my aesthetician. I like the formula and am excited to be on the Paula's Choice train. I will explore other Paula's Choice serums and products based on how nice and effective this one is.
Report this reviewHave not seen result
I'm halfway done with my first bottle but I have not seen any result yet. I'll be patient with this one to see if I'll see result when I finish my first bottle
Report this reviewAffordable and Moisturizing
I thought this was an affordable and moisturizing niacinamide option. It didn't break me out, and I have sensitive acne-prone skin. The serum takes a minute or two to soak in and can leave a sheen so I use it at night before bed instead of the daytime. It seems to be helping to fade my acne scars.
Report this reviewDecent product!
Liked how the product went on my skin—much less sticky than other niacinamide serums i’ve tried in the past. Not sure if I think it significantly changed my skin texture or acne but also didn’t irritate or make worse.
Report this reviewGame changer
This is what made my enlarged pores unable to be seen without a magnifying mirror. My nose pores stay completely clean and my nose looks poreless. I've always tried many products, and my enlarged pores have always been an issue I've tried to better, but this one was the game changer. I now have the results I sought for years.
Report this reviewGood, but not that good
Its okay, honestly but I dont think it is working for me, and I wont repurchase it
Report this reviewBUY IT
This product has really helped smooth out my skin! Will continue to repurchase
Report this review