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Skin Care Treatments and Serums

3724 results

Whatever you're facing, our selection of treatments is here to help. These efficacious, high-quality masks, oils and creams are formulated to target acne, dark spots, rosacea, aging skin and other skin concerns. These skin care treatments are the best of the best—many are backed by clinical trials and have rave customer reviews.

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Products

  • SkinCeuticals C E Ferulic (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.76 Stars 4412 Reviews
    $169.00
  • Sunday Riley GOOD GENES All-In-One Lactic Acid Treatment (1.7 oz. - $175 Value)

    4.65 Stars 655 Reviews
    $122.00
  • SkinMedica TNS Advanced+ Serum (1 oz.)

    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26)
    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26) Value $29.00

    $29 SkinMedica Gift

    Receive a Skinmedica Vitamin C+E Complex 0.25 oz ($29 value) when you spend $160 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.57 Stars 223 Reviews
    $295.00
  • iS Clinical Active Serum (1 fl. oz.)

    4.64 Stars 440 Reviews
    $142.00
  • SkinCeuticals Triple Lipid Restore 242 (1.6 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.8 Stars 1655 Reviews
    $136.00
  • SkinCeuticals Silymarin CF (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.36 Stars 76 Reviews
    $169.00
  • SkinMedica Neck Correct Cream (2 oz.)

    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26)
    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26) Value $29.00

    $29 SkinMedica Gift

    Receive a Skinmedica Vitamin C+E Complex 0.25 oz ($29 value) when you spend $160 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.0 Stars 18 Reviews
    $135.00
  • SkinCeuticals Serum 10 AOX (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.62 Stars 125 Reviews
    $72.00
  • SkinMedica TNS Essential Serum (1 oz.)

    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26)
    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26) Value $29.00

    $29 SkinMedica Gift

    Receive a Skinmedica Vitamin C+E Complex 0.25 oz ($29 value) when you spend $160 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.62 Stars 584 Reviews
    $281.00
  • Sunday Riley A High-Dose Retinoid Serum (1.7 fl. oz.)

    4.78 Stars 40 Reviews
    $122.00
  • Sunday Riley GOOD GENES Glycolic Acid Treatment (1.7 fl. oz.)

    4.57 Stars 69 Reviews
    $122.00
  • Eminence Organic Skin Care Strawberry Rhubarb Hyaluronic Serum 1 fl. oz

    4.61 Stars 339 Reviews
    $48.00
  • SkinCeuticals Phloretin CF (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.73 Stars 616 Reviews
    $169.00
  • PCA SKIN Hyaluronic Acid Boosting Serum (1 oz.)

    PCA SKIN Rejuvenate and Hydrate Duo
    PCA SKIN Rejuvenate and Hydrate Duo Value $33.50

    $32 PCA Skin Gift

    Receive a PCA SKIN Rejuvenate and Hydrate Duo (worth $32) when you spend $100 on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.76 Stars 235 Reviews
    $120.00
  • Revision Skincare® C+ Correcting Complex 30%™ 1 fl. oz.

    4.69 Stars 98 Reviews
    $164.00
  • SkinCeuticals Blemish + Age Defense (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.7 Stars 605 Reviews
    $96.00
  • Sunday Riley A High-Dose Retinoid Serum (1 fl. oz.)

    4.56 Stars 123 Reviews
    $85.00
  • Revision Skincare® Revox 7 0.5 fl. oz.

    4.74 Stars 38 Reviews
    $130.00
  • SkinCeuticals Phloretin CF Gel (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.73 Stars 84 Reviews
    $169.00
  • SkinCeuticals Phyto Plus (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.46 Stars 127 Reviews
    $87.00
  • Paula's Choice C15 Super Booster (0.67 fl. oz.)

    4.49 Stars 214 Reviews
    $52.00
  • Eminence Organic Skin Care Clear Skin Willow Bark Booster-Serum 1 fl. oz

    4.57 Stars 68 Reviews
    $56.00
  • Obagi Medical Professional-C Serum 20% (1 fl. oz.)

    4.74 Stars 866 Reviews
    $136.99
  • Revision Skincare® Nectifirm ADVANCED 1.7 oz.

    4.59 Stars 66 Reviews
    $142.00
  • NEOSTRATA Triple Firming Anti-aging Neck Cream (2.8 oz.)

    4.62 Stars 82 Reviews
    $88.00
  • Paula's Choice CLINICAL Niacinamide 20 Treatment (0.67 fl. oz.)

    4.56 Stars 43 Reviews
    $50.00
  • Paula's Choice 10 Niacinamide Booster (0.67 oz.)

    4.43 Stars 118 Reviews
    $46.00
  • Paula's Choice Hyaluronic Acid Booster (0.5 fl. oz.)

    4.49 Stars 57 Reviews
    $36.00
  • PCA Skin Hyaluronic Acid Boosting Serum 3 fl. oz.

    PCA SKIN Rejuvenate and Hydrate Duo
    PCA SKIN Rejuvenate and Hydrate Duo Value $33.50

    $32 PCA Skin Gift

    Receive a PCA SKIN Rejuvenate and Hydrate Duo (worth $32) when you spend $100 on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    $299.00
  • PCA SKIN Resveratrol Restorative Complex (1 oz.)

    PCA SKIN Rejuvenate and Hydrate Duo
    PCA SKIN Rejuvenate and Hydrate Duo Value $33.50

    $32 PCA Skin Gift

    Receive a PCA SKIN Rejuvenate and Hydrate Duo (worth $32) when you spend $100 on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    3.8 Stars 5 Reviews
    $120.00
  • EltaMD UV Clear Broad-Spectrum SPF 46 (1.7 oz.)

    4.8 Stars 4367 Reviews
    $39.00
  • EltaMD UV Clear Broad-Spectrum SPF 46 - Tinted (1.7 oz.)

    4.74 Stars 1146 Reviews
    $41.00
  • EltaMD UV Daily Tinted Broad-Spectrum SPF 40 (1.7 oz.)

    4.73 Stars 383 Reviews
    $34.50
  • EltaMD UV Elements Tinted Broad-Spectrum SPF 44 (2 oz.)

    4.66 Stars 859 Reviews
    $38.50
  • EltaMD UV Aero Broad-Spectrum SPF 45 (6 oz.)

    4.59 Stars 97 Reviews
    $36.50
  • SkinCeuticals A.G.E. Eye Complex (0.5 oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.6 Stars 1005 Reviews
    $105.00
  • Paula's Choice SKIN PERFECTING 2 BHA Liquid Exfoliant (4 fl. oz.)

    4.66 Stars 683 Reviews
    $32.00
  • EltaMD UV Daily Broad-Spectrum SPF 40 (1.7 oz.)

    4.82 Stars 697 Reviews
    $32.50
  • EltaMD AM Therapy Facial Moisturizer (1.7 oz.)

    4.79 Stars 685 Reviews
    $39.00
  • EltaMD UV Physical Broad-Spectrum SPF 41 Sunscreen - Tinted (3 oz.)

    4.69 Stars 943 Reviews
    $36.50
  • iS Clinical Cleansing Complex (6 fl. oz.)

    4.82 Stars 857 Reviews
    $45.00
  • SkinCeuticals Hydrating B5 Gel (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.69 Stars 897 Reviews
    $86.00
  • SkinMedica AHA/BHA Exfoliating Cleanser (6 fl. oz.)

    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26)
    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26) Value $29.00

    $29 SkinMedica Gift

    Receive a Skinmedica Vitamin C+E Complex 0.25 oz ($29 value) when you spend $160 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.87 Stars 344 Reviews
    $48.00
  • COSRX Acne Pimple Master Patch (24 count)

    4.66 Stars 479 Reviews
    $6.00
  • SkinCeuticals Purifying Cleanser (6.8 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.67 Stars 230 Reviews
    $36.00