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Night Treatments & Serums

834 results

Complete your bedtime skin care routine with a night serum. Our selection of night serums for your face addresses common skin problems and provides nourishment. Consistently known to be more lightweight than moisturizers, serums contain high concentrations of active ingredients that help target specific skin concerns and make them perfect for nighttime wear. Are you looking to decrease dark spots? Choose a brightening night serum with ingredients that help reduce discoloration like kojic acid and niacinamide. To improve the appearance of fine lines, consider a night skin treatment with retinol that may aid in reducing the appearance of wrinkles. 
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  • SkinCeuticals Triple Lipid Restore 242 (1.6 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.8 Stars 1959 Reviews
    $150.00
  • SkinCeuticals A.G.E. Eye Complex (0.5 oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.59 Stars 1145 Reviews
    $105.00
  • SkinCeuticals Hyaluronic Acid Intensifier (1 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.76 Stars 1151 Reviews
    $110.00
  • Paula's Choice SKIN PERFECTING 2 BHA Liquid Exfoliant (4 fl. oz.)

    4.66 Stars 755 Reviews
    $34.00
  • SkinCeuticals Hydrating B5 Gel (1 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.7 Stars 1007 Reviews
    $90.00
  • EltaMD PM Therapy Facial Moisturizer (1.7 oz.)

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    4.58 Stars 595 Reviews
    $41.00
  • Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant - Trial Size (30ml)

    4.66 Stars 35 Reviews
    $13.00
  • SkinCeuticals Daily Moisture (2 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.62 Stars 624 Reviews
    $76.00
  • COSRX Acne Pimple Master Patch (24 count)

    4.6 Stars 553 Reviews
    $6.00
  • EltaMD Foaming Facial Cleanser (7 oz.)

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    4.68 Stars 622 Reviews
    $32.00
  • SkinCeuticals LHA Cleanser Gel (8 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.67 Stars 549 Reviews
    $42.00
  • SkinCeuticals Blemish + Age Defense (1 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.68 Stars 661 Reviews
    $106.00
  • SkinCeuticals Renew Overnight Dry (2 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.49 Stars 241 Reviews
    $76.00
  • SkinCeuticals Emollience (2 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.72 Stars 350 Reviews
    $76.00
  • SkinCeuticals Retinol 1.0 Maximum Strength Refining Night Cream (1 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.7 Stars 452 Reviews
    $100.00
  • SkinCeuticals LHA Toner (6.8 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.6 Stars 187 Reviews
    $41.00
  • SkinCeuticals Discoloration Defense (1 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.32 Stars 466 Reviews
    $108.00
  • PCA SKIN Hyaluronic Acid Boosting Serum (1 oz.)

    4.74 Stars 271 Reviews
    $124.00
  • SkinCeuticals Retinol 0.5 Refining Night Cream (1 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.76 Stars 372 Reviews
    $88.00
  • SkinCeuticals Retinol 0.3 (1 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.75 Stars 244 Reviews
    $78.00
  • SkinCeuticals Clarifying Exfoliating Cleanser (5 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.64 Stars 77 Reviews
    $36.00
  • Peter Thomas Roth Water Drench Hyaluronic Cloud Hydra-Gel Eye Patches (30 pair)

    4.77 Stars 108 Reviews
    $55.00
  • SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)

    SkinMedica Brightening Essentials Gift Set (Worth $130)
    SkinMedica Brightening Essentials Gift Set (Worth $130) Value $130.00

    $130 SkinMedica Gift

    Receive a SkinMedica Brightening Essentials Gift Set ($130 value) when you spend $200 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.85 Stars 308 Reviews
    $96.00
  • SkinCeuticals A.G.E. Interrupter (1.7 oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.66 Stars 238 Reviews
    $168.00
  • EltaMD Barrier Renewal Complex (1.7 oz.)

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    4.44 Stars 181 Reviews
    $58.00
  • SkinCeuticals Resveratrol B E (1 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.57 Stars 327 Reviews
    $168.00
  • SkinCeuticals Glycolic 10 Renew Overnight (1.7 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.79 Stars 273 Reviews
    $90.00
  • SkinCeuticals Purifying Cleanser (6.8 fl. oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.59 Stars 278 Reviews
    $36.00
  • COSRX Advanced Snail 96 Mucin Power Essence (3.38 fl. oz.)

    4.6 Stars 326 Reviews
    $25.00
  • EltaMD Renew Eye Gel - Daily Eye Therapy (0.5 fl. oz.)

    Triple Points

    Earn 3x Dermstore Rewards Points on EltaMD. 3x points = 15% back in rewards to spend on future purchases at Dermstore.com. EltaMD event ends 2/8/23 at 11:59 p.m. PT.
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    4.56 Stars 279 Reviews
    $62.00
  • Paula's Choice C15 Super Booster (0.67 fl. oz.)

    4.46 Stars 241 Reviews
    $55.00
  • SkinCeuticals Eye Balm (0.5 oz.)

    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00)
    SkinCeuticals Triple Lipid Restore 2:4:2 4ml (Worth $11.00) Value $11.00

    $11 SkinCeuticals Gift

    Receive a SkinCeuticals Triple Lipid Restore 2:4:2 4ml ($11 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    4.58 Stars 144 Reviews
    $90.00
  • Obagi Medical Hydrate Luxe (1.7 oz.)

    4.75 Stars 207 Reviews
    $75.00
  • SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)

    SkinMedica Brightening Essentials Gift Set (Worth $130)
    SkinMedica Brightening Essentials Gift Set (Worth $130) Value $130.00

    $130 SkinMedica Gift

    Receive a SkinMedica Brightening Essentials Gift Set ($130 value) when you spend $200 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.81 Stars 240 Reviews
    $64.00