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Night Treatments & Serums

567 results

Complete your bedtime skin care routine with a night serum. Our selection of night serums for your face addresses common skin problems and provides nourishment. Consistently known to be more lightweight than moisturizers, serums contain high concentrations of active ingredients that help target specific skin concerns and make them perfect for nighttime wear. Are you looking to decrease dark spots? Choose a brightening night serum with ingredients that help reduce discoloration like kojic acid and niacinamide. To improve the appearance of fine lines, consider a night skin treatment with retinol that may aid in reducing the appearance of wrinkles. 
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Products

  • SkinCeuticals Triple Lipid Restore 242

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
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    $155.00
  • SkinCeuticals Hyaluronic Acid Intensifier

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $110.00
  • SkinCeuticals A.G.E Advanced Eye Cream

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $116.00
  • SkinCeuticals Hydrating B5 Gel

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $90.00
  • SkinCeuticals Micro-Exfoliating Scrub (5 fl. oz.)

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $35.00
  • EltaMD PM Restore Facial Moisturizer

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
    JOIN NOW
    $44.00
  • SkinCeuticals Daily Moisture

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $78.00
  • COSRX Acne Pimple Master Patch (24 count)

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
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    $6.00
  • Paula's Choice SKIN PERFECTING 2 BHA Liquid Exfoliant (4 fl. oz.)

    Paula's Choice Clarify and Even Duo ($14 Value)
    Paula's Choice Clarify and Even Duo ($14 Value) Value $14.00

    $14 Gift

    Receive a Paula's Choice Clarify and Even Duo ($14 value) when you spend $50 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
    SHOP NOW
    $35.00
  • PCA SKIN Hyaluronic Acid Boosting Serum

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
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    $125.00
  • Sunday Riley Good Genes All-In-One Lactic Acid Treatment 1.7oz

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
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    $122.00
  • Obagi Medical Hydrate Luxe (1.7 oz.)

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
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    $78.00
  • SkinCeuticals LHA Cleanser Gel

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $45.00
  • SkinCeuticals Blemish + Age Defense

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $110.00
  • Elemis Pro-Collagen Cleansing Balm 100g

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
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    $69.00
  • EltaMD Foaming Facial Cleanser (7 oz.)

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
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    $35.00
  • SkinCeuticals Purifying Cleanser (6.8 fl. oz.)

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $39.00
  • Augustinus Bader The Rich Cream 50ml

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
    JOIN NOW
    $300.00
  • La Roche-Posay Toleriane Double Repair Moisturizer (Various Sizes)

    La Roche-Posay Anthelios Ultra-Light Sunscreen Fluid SPF 60 0.17 fl. oz (Worth $4.30)
    La Roche-Posay Anthelios Ultra-Light Sunscreen Fluid SPF 60 0.17 fl. oz (Worth $4.30) Value $4.30

    La Roche-Posay Gift

    Receive a La Roche-Posay Anthelios Ultra-Light Sunscreen Fluid SPF 60 5ml ($4 value) when you spend $75 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last. Participating products only.
    SHOP NOW
    $23.99
  • SkinCeuticals Discoloration Defense

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $110.00
  • SkinCeuticals Retinol 1.0 Maximum Strength Refining Night Cream

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $102.00
  • La Roche-Posay Toleriane Hydrating Gentle Cleanser (Various Sizes)

    La Roche-Posay Anthelios Ultra-Light Sunscreen Fluid SPF 60 0.17 fl. oz (Worth $4.30)
    La Roche-Posay Anthelios Ultra-Light Sunscreen Fluid SPF 60 0.17 fl. oz (Worth $4.30) Value $4.30

    La Roche-Posay Gift

    Receive a La Roche-Posay Anthelios Ultra-Light Sunscreen Fluid SPF 60 5ml ($4 value) when you spend $75 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last. Participating products only.
    SHOP NOW
    $17.99
  • SkinCeuticals Phyto Corrective Gel

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $80.00
  • COSRX Advanced Snail 96 Mucin Power Essence (3.38 fl. oz.)

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
    JOIN NOW
    $25.00
  • SkinMedica Even and Correct Brightening Treatment Pads - 60 Pads

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
    SHOP NOW
    $60.00
  • SkinCeuticals LHA Toner (6.8 fl. oz.)

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $44.00
  • SkinCeuticals A.G.E. Interrupter Advanced Anti-Wrinkle Cream (1.7 fl. oz.)

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $185.00
  • SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
    SHOP NOW
    $96.00
  • SkinCeuticals Emollience (2 fl. oz.)

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $78.00
  • SkinMedica Age Defense Retinol Complex 0.5 (1 fl. oz.)

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
    SHOP NOW
    $80.00
  • SkinCeuticals Renew Overnight Dry (2 fl. oz.)

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $78.00
  • SkinCeuticals Phyto A+ Brightening Treatment Lightweight Moisturizer

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $110.00
  • Sunday Riley C.E.O. 15% Vitamin C Brightening Serum 1 fl. oz

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
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    $85.00
  • SkinCeuticals Antioxidant Lip Repair (0.34 fl. oz.)

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $46.00
  • EltaMD Barrier Renewal Complex (1.7 oz.)

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
    JOIN NOW
    $59.00
  • SkinCeuticals Resveratrol B E

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $168.00
  • SkinCeuticals Retinol 0.5

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $90.00
  • Augustinus Bader The Rich Cream 30ml

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
    JOIN NOW
    $185.00
  • SkinCeuticals Metacell Renewal B3 (1.7 fl. oz.)

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    DOUBLE POINTS + Gift

    Earn 2x Dermstore Rewards Points on SkinCeuticals. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. Event ends 7/19/2024 at 11:59 p.m. PT.
    SHOP NOW
    $130.00
  • SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
    SHOP NOW
    $64.00
  • Sunday Riley GOOD GENES All-In-One Lactic Acid Treatment (1 fl. oz.)

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
    JOIN NOW
    $85.00
  • Augustinus Bader The Cream 50ml

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
    JOIN NOW
    $300.00
  • Epionce Daily Shield Lotion Tinted SPF 50 1.7 fl. oz.

    Exclusive | Members Only Event

    Become a Dermstore Rewards Member for exclusive access to our Members Only Event. Save Up to 25% and earn 5% back on every purchase, always. It takes 24 hours to enter the event after sign up. 
    JOIN NOW
    $42.00
  • Paula's Choice 10 Azelaic Acid Booster (1 fl. oz.)

    Paula's Choice Clarify and Even Duo ($14 Value)
    Paula's Choice Clarify and Even Duo ($14 Value) Value $14.00

    $14 Gift

    Receive a Paula's Choice Clarify and Even Duo ($14 value) when you spend $50 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
    SHOP NOW
    $39.00