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Wrinkle Creams and Fine Line Treatments

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  • Sponsored

    Obagi Medical Daily Hydro-Drops Facial Serum (1 fl. oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $105.00
  • SkinCeuticals C E Ferulic

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
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    $182.00
  • Dr. Whitney Bowe Beauty Asta C Vitamin C Age Defense Serum (1 fl oz)

    Dermstore Exclusive

    This product is exclusive to Dermstore - a one-of-a-kind available nowhere else. Limited quantity available. 
    VIEW ALL EXCLUSIVES
    $88.00
  • SkinCeuticals Triple Lipid Restore 242

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
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    $155.00
  • Obagi Medical Professional-C Serum 20%

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $142.00
  • SkinMedica TNS Advanced+ Serum

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
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    $295.00
  • Sunday Riley Good Genes All-In-One Lactic Acid Treatment 1.7oz

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $122.00
  • iS Clinical Pro-Heal Serum Advance+ 30ml

    iS Clinical Active Serum 3.75ml (Worth $22.00)
    iS Clinical Active Serum 3.75ml (Worth $22.00) Value $22.00

    $22 Gift

    Receive an iS Clinical Active Serum 3.75ml ($22 value) when you spend $125 or more on the brand. Complimentary Gift will be awarded in cart, while supplies last. Participating products only.
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    $158.00
  • SkinMedica HA5 Rejuvenating Hydrator

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
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    $184.00
  • PCA SKIN Hyaluronic Acid Boosting Serum

    20% off Auto-Replenishment

    Enjoy 20% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $125.00
  • Obagi Medical Retinol 1.0 (1 oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $79.00
  • Dr. Whitney Bowe Beauty Retinal Night Advanced 0.1% Retinal Firming Treatment (0.95 fl oz)

    Dermstore Exclusive

    This product is exclusive to Dermstore - a one-of-a-kind available nowhere else. Limited quantity available. 
    VIEW ALL EXCLUSIVES
    $99.00
  • Paula's Choice 10 Niacinamide Booster (0.67 oz.)

    Paula's Choice Clarify and Even Duo ($14 Value)
    Paula's Choice Clarify and Even Duo ($14 Value) Value $14.00

    $14 Gift

    Receive a Paula's Choice Clarify and Even Duo ($14 value) when you spend $50 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    $49.00
  • SkinCeuticals Hyaluronic Acid Intensifier

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $110.00
  • SkinCeuticals Hydrating B5 Gel

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $90.00
  • Obagi Medical Professional-C Serum 15% (1 fl. oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $115.00
  • SkinCeuticals Phloretin CF

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $182.00
  • SkinCeuticals Blemish + Age Defense

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $110.00
  • Revision Skincare C+ Correcting Complex 30%

    Auto-Replenishment

    Enjoy your favorites at your ferquency. Not only do you choose your frequency, but you get FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $185.00
  • SkinCeuticals Phyto Corrective Gel

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $80.00
  • iS Clinical Active Serum

    iS Clinical Active Serum 3.75ml (Worth $22.00)
    iS Clinical Active Serum 3.75ml (Worth $22.00) Value $22.00

    $22 Gift

    Receive an iS Clinical Active Serum 3.75ml ($22 value) when you spend $125 or more on the brand. Complimentary Gift will be awarded in cart, while supplies last. Participating products only.
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    $142.00
  • SkinCeuticals Retinol 1.0 Maximum Strength Refining Night Cream

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $102.00
  • SkinCeuticals Silymarin CF

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $182.00
  • SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
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    $96.00
  • SkinCeuticals Resveratrol B E

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $168.00
  • Obagi Medical Daily Hydro-Drops Facial Serum (1 fl. oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
    SHOP NOW
    $105.00
  • SkinCeuticals Retinol 0.5

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $90.00
  • Jan Marini C-ESTA Face Serum (1 fl. oz.)

    Auto-Replenishment

    Enjoy your favorites at your ferquency. Not only do you choose your frequency, but you get FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
    SHOP NOW
    $129.00
  • iS Clinical Pro-Heal Serum Advance+ 15ml

    iS Clinical Active Serum 3.75ml (Worth $22.00)
    iS Clinical Active Serum 3.75ml (Worth $22.00) Value $22.00

    $22 Gift

    Receive an iS Clinical Active Serum 3.75ml ($22 value) when you spend $125 or more on the brand. Complimentary Gift will be awarded in cart, while supplies last. Participating products only.
    SHOP NOW
    $95.00
  • SkinMedica Age Defense Retinol Complex 0.5 (1 fl. oz.)

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
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    $80.00
  • Neocutis BIO SERUM FIRM Rejuvenating Growth Factor & Peptide Treatment

    20% off Auto-Replenishment

    Enjoy 20% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
    SHOP NOW
    $290.00
  • SkinMedica Vitamin C + E Complex (1 oz.)

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
    SHOP NOW
    $106.00
  • Sunday Riley A+ High-Dose Retinoid Serum 1.7 oz

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
    SHOP NOW
    $122.00
  • Sunday Riley C.E.O. Glow Vitamin C Turmeric Face Oil (1.18 fl. oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $80.00
  • Paula's Choice 10 Azelaic Acid Booster (1 fl. oz.)

    Paula's Choice Clarify and Even Duo ($14 Value)
    Paula's Choice Clarify and Even Duo ($14 Value) Value $14.00

    $14 Gift

    Receive a Paula's Choice Clarify and Even Duo ($14 value) when you spend $50 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
    SHOP NOW
    $39.00
  • Paula's Choice C15 Super Booster 20ml

    Paula's Choice Clarify and Even Duo ($14 Value)
    Paula's Choice Clarify and Even Duo ($14 Value) Value $14.00

    $14 Gift

    Receive a Paula's Choice Clarify and Even Duo ($14 value) when you spend $50 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
    SHOP NOW
    $55.00
  • Sunday Riley GOOD GENES All-In-One Lactic Acid Treatment (1 fl. oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
    SHOP NOW
    $85.00
  • SkinCeuticals Metacell Renewal B3 (1.7 fl. oz.)

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $130.00
  • SkinCeuticals P-TIOX Anti-Wrinkle Peptide Serum

    New Arrival + Gift

    Shop new arrivals to discover the latest in beauty, skin and hair care and stock up on seasonal must-haves and everyday essentials. Plus, receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand.
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    $148.00
  • Cell Cycle Catalyst Exfoliating Booster Serum (1 fl. oz.)

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $115.00
  • SkinCeuticals Glycolic 10 Renew Overnight (1.7 fl. oz.)

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $96.00
  • SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
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    $64.00
  • Obagi Medical ELASTIderm Facial Serum (1 fl. oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
    SHOP NOW
    $215.00
  • Peter Thomas Roth Water Drench Hyaluronic Cloud Hydra-Gel Eye Patches (30 pair)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $55.00
  • SkinMedica TNS Recovery Complex (1 fl. oz.)

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
    SHOP NOW
    $230.00
  • Sunday Riley C.E.O. Vitamin C Rich Hydration Cream (1.7 oz)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $65.00
It happens to everyone, sooner or later. One day, you're admiring your smooth, tight and glowing skin in the mirror and (seemingly) the next day, your complexion has sprouted enough fine lines and wrinkles to cause you alarm. So what can you do? Browse our curated selection of wrinkle creams that include key ingredients like peptides, retinols and plant stem cells, all of which support and strengthen the growth, reproduction and revival of your skin cells. Drinking lots of water, quitting smoking and wearing sunscreen are also essential behavioral changes for anyone seeking a wrinkle-free complexion.