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SkinCeuticals Discoloration Defense (1 fl. oz.)

A skin-brightening serum clinically proven to correct dark spots.

SkinCeuticals' Discoloration Defense is clinically proven to reduce the appearance of dark spots and discoloration on the face. Powered by kojic acid, tranexamic acid and vitamin B3, this advanced formula is a hydroquinone-free skin brightening serum.

Key Ingredients:

  • 3% Tranexamic Acid: minimizes the recurrence of discoloration and stubborn brown patches with continued use
  • 1% Kojic Acid: naturally produced by certain fungi, kojic acid helps improve skin brightness
  • 5% Niacinamide (Vitamin B3): a water-soluble vitamin that has been shown to help reduce the appearance of skin discoloration
  • 5% HEPES: a synthetically-derived acid that activates natural enzymes in skin to help break the bonds that bind dead skin cells to the surface for even exfoliation

Key Benefits:

  • Features a synergistic blend of anti-discoloration ingredients to reduce the appearance of skin discoloration, improve brightness, and minimize the reoccurrence of discoloration (with continued use)
  • 60% average improvement in the appearance of stubborn brown patches
  • Paraben-free, fragrance-free, silicone-free, gluten-free, and hydroquinone-free
  • Ideal at-home complement to professional skin discoloration treatments, such as chemical peels or non-ablative laser; always consult with a physician for individual regimen recommendations

Clinical Studies:

In a 12-week clinical study*, Discoloration Defense significantly improved the appearance of key skin discoloration markers on Fitzpatrick I-IV skin tones:

  • 60% average improvement in the appearance of stubborn brown patches
  • 59% average improvement in the appearance of skin discoloration
  • 81% average improvement in the appearance of post-acne marks
  • 59% average improvement in the appearance of even skin tone

In a 12-week study** on deeper skin tones (Fitzpatrick V-VI), twice-daily application of Discoloration Defense demonstrated a statistically-significant improvement in the appearance of discoloration, post-inflammatory discoloration, and even skin tone:

  • 33% reduction in hyperpigmentation at 12 weeks
  • 34% reduction in post-inflammatory hyperpigmentation at 12 weeks

Learn more on the blog: How to incorporate this serum into your SkinCeuticals regimen.

*A 12-week, single-center, clinical study was conducted on 50 females, ages 25 to 60, Fitzpatrick I-IV, with mild-to-moderate facial skin discoloration, including stubborn dark spots, post-acne marks and uneven skin tone. Discoloration Defense was applied to the face twice a day in conjunction with a sunscreen. Efficacy and tolerability evaluations were conducted at baseline and at weeks 2, 4, 8, and 12.

**A 12-week, single-center, clinical study was conducted on 51 female subjects, Fitzpatrick V-VI, with visible signs of skin discoloration/hyperpigmentation, including post-inflammatory hyperpigmentation and melasma. Discoloration Defense was applied to the face twice a day in conjunction with a sunscreen. Efficacy and tolerability evaluations were conducted at baseline and at weeks 2, 4, 8, and 12.

Twice daily, apply three to five drops to face. For morning use, apply after a SkinCeuticals vitamin C serum and follow with a SkinCeuticals broad-spectrum SPF 50+ sunscreen and limit sun exposure while using this product. Do not use on irritated or broken skin. If irritation occurs, discontinue use.

Aqua/Water, Butylene Glycol, Niacinamide, Hydroxyethylpiperazine Ethane Sulfonic Acid, Glycerin, Tranexamic Acid, Propylene Glycol, Hydroxyethyl Urea, Kojic Acid, Caprylyl Glycol, Allantoin, Chlorphenesin, Xanthan Gum, Disodium Edta.

Range:
Correct
Brand:
SkinCeuticals
Volume:
30ml

Frequently Bought Together

SkinCeuticals Discoloration Defense (1 fl. oz.)
This item
SkinCeuticals Discoloration Defense (1 fl. oz.)
$98.00
SkinCeuticals Discoloration Defense (1 fl. oz.) + SkinCeuticals C E Ferulic (1 fl. oz.)

Total Price: $264.00

Add both to cart
SkinCeuticals Discoloration Defense (1 fl. oz.)
This item
SkinCeuticals Discoloration Defense (1 fl. oz.)
$98.00
Add both to cart

SkinCeuticals Discoloration Defense (1 fl. oz.)

A skin-brightening serum clinically proven to correct dark spots.

Earn 490 reward points when purchasing this product as a rewards member*

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SkinCeuticals' Discoloration Defense is clinically proven to reduce the appearance of dark spots and discoloration on the face. Powered by kojic acid, tranexamic acid and vitamin B3, this advanced formula is a hydroquinone-free skin brightening serum.

Key Ingredients:

  • 3% Tranexamic Acid: minimizes the recurrence of discoloration and stubborn brown patches with continued use
  • 1% Kojic Acid: naturally produced by certain fungi, kojic acid helps improve skin brightness
  • 5% Niacinamide (Vitamin B3): a water-soluble vitamin that has been shown to help reduce the appearance of skin discoloration
  • 5% HEPES: a synthetically-derived acid that activates natural enzymes in skin to help break the bonds that bind dead skin cells to the surface for even exfoliation

Key Benefits:

  • Features a synergistic blend of anti-discoloration ingredients to reduce the appearance of skin discoloration, improve brightness, and minimize the reoccurrence of discoloration (with continued use)
  • 60% average improvement in the appearance of stubborn brown patches
  • Paraben-free, fragrance-free, silicone-free, gluten-free, and hydroquinone-free
  • Ideal at-home complement to professional skin discoloration treatments, such as chemical peels or non-ablative laser; always consult with a physician for individual regimen recommendations

Clinical Studies:

In a 12-week clinical study*, Discoloration Defense significantly improved the appearance of key skin discoloration markers on Fitzpatrick I-IV skin tones:

  • 60% average improvement in the appearance of stubborn brown patches
  • 59% average improvement in the appearance of skin discoloration
  • 81% average improvement in the appearance of post-acne marks
  • 59% average improvement in the appearance of even skin tone

In a 12-week study** on deeper skin tones (Fitzpatrick V-VI), twice-daily application of Discoloration Defense demonstrated a statistically-significant improvement in the appearance of discoloration, post-inflammatory discoloration, and even skin tone:

  • 33% reduction in hyperpigmentation at 12 weeks
  • 34% reduction in post-inflammatory hyperpigmentation at 12 weeks

Learn more on the blog: How to incorporate this serum into your SkinCeuticals regimen.

*A 12-week, single-center, clinical study was conducted on 50 females, ages 25 to 60, Fitzpatrick I-IV, with mild-to-moderate facial skin discoloration, including stubborn dark spots, post-acne marks and uneven skin tone. Discoloration Defense was applied to the face twice a day in conjunction with a sunscreen. Efficacy and tolerability evaluations were conducted at baseline and at weeks 2, 4, 8, and 12.

**A 12-week, single-center, clinical study was conducted on 51 female subjects, Fitzpatrick V-VI, with visible signs of skin discoloration/hyperpigmentation, including post-inflammatory hyperpigmentation and melasma. Discoloration Defense was applied to the face twice a day in conjunction with a sunscreen. Efficacy and tolerability evaluations were conducted at baseline and at weeks 2, 4, 8, and 12.

Twice daily, apply three to five drops to face. For morning use, apply after a SkinCeuticals vitamin C serum and follow with a SkinCeuticals broad-spectrum SPF 50+ sunscreen and limit sun exposure while using this product. Do not use on irritated or broken skin. If irritation occurs, discontinue use.

Aqua/Water, Butylene Glycol, Niacinamide, Hydroxyethylpiperazine Ethane Sulfonic Acid, Glycerin, Tranexamic Acid, Propylene Glycol, Hydroxyethyl Urea, Kojic Acid, Caprylyl Glycol, Allantoin, Chlorphenesin, Xanthan Gum, Disodium Edta.

Range:
Correct
Brand:
SkinCeuticals
Volume:
30ml

Frequently Bought Together

SkinCeuticals Discoloration Defense (1 fl. oz.)
This item
SkinCeuticals Discoloration Defense (1 fl. oz.)
$98.00
SkinCeuticals Discoloration Defense (1 fl. oz.) + SkinCeuticals C E Ferulic (1 fl. oz.)

Total Price: $264.00

Add both to cart
SkinCeuticals Discoloration Defense (1 fl. oz.)
This item
SkinCeuticals Discoloration Defense (1 fl. oz.)
$98.00
Add both to cart

Customer Reviews

Overall Rating : 4.39 / 5 (354 Reviews)
  • 231 5 star reviews
  • 65 4 star reviews
  • 36 3 star reviews
  • 10 2 star reviews
  • 12 1 star reviews
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Top Customer Reviews

Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.

Reward members earn 50 points for every review written on verified purchases.

Husband approves

My husband had sun spots that have faded greatly over 3 months daily use! 

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Even Skin Tone

This has helped even put my skin tone with just a few uses.  

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Great serum

My go to with phlorentin vitamin C. The combo does wonders for dark spots. 

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Fading marks

It’s not a quick fix, but I do think overall it’s helping to even and improve my skin tone 

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Excellent for acne scars

This is my favorite product for helping to eliminate post acne hyperpigmentation.  It had a hearty price tag, but it’s worth it as results are evident.  Very gentle on sensitive skin,

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Coming back for more

I’ve bought this product twice and and am enjoying the benefits. I do use a variety of products but this has been a nice bonus while I’m pausing my Hydroquinone use and I still want to see benefits to combat my hyperpigmentation.

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Effective

The trial size I received was so effective that I went ahead and purchased the full size!

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I had high hopes

This has not worked. I have some slight discoloration on my upper lip. I’d hoped  it would help. Nada. 2 stars because hope springs eternal.

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Effective

After using the trial size sample, this product's efficacy was enough to convince me to purchase the full size!

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Received bad bottle

So the bottle I got was in a dark amber color. I used it 2-3 times and had a reaction. My skin turned red. So I stopped. I do have very sensitive skin. I don’t know if I got a bad one or it’s just wasn’t for my skin. But it wasn’t in a light yellow color and it was dark amber which meant it wasn’t as effective 

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