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SkinCeuticals Glycolic 10 Renew Overnight (1.7 fl. oz.)
A night cream made with 10% glycolic acid to improve the appearance of skin tone and texture.
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4 installments of $22.50 with Klarna Learn more
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4 installments of $22.50 with afterpay Learn more
Formulated with 10% glycolic acid, SkinCeuticals' Glycolic 10 Renew Overnight is clinically proven* to promote a brighter, clearer-looking complexion. This powerful face cream is complete with two-percent phytic acid, natural oils and botanicals that promote skin clarity and deep hydration.
Key Ingredients:
- 10% Glycolic Free Acid Value: derived from sugar cane, this powerful fruit acid helps stimulate skin’s natural exfoliation process and minimizes the buildup of dead skin cells, resulting in improvement in the appearance of skin texture and tone.
- 2% Phytic Acid: naturally present in legumes and seeds, this potent ingredient provides dual-action exfoliation and skin brightening effects. It helps to inhibit the impact of skin aggressors that can cause dullness, promoting skin clarity and glow.
- 1% Soothing Complex: featuring a combination of natural oils and botanicals, including jojoba and sunflower seed, this wax forms a protective, breathable layer on skin to help lock in hydration and provide comfort.
Key Benefits:
- Tested tolerable for nightly use
- Accelerates cellular turnover and refines skin texture
- Alcohol-, oil-, fragrance- and dye-free
Clinical Studies:
In an 8-week clinical study, Glycolic 10 Renew Overnight significantly improved the appearance of key markers of glowing skin*:
- 36% average improvement in radiance
- 37% average improvement in skin texture
- 19% average improvement in skin tone
*An 8-week, single-center, clinical study was conducted on 52 females, ages 35-64, with global fine lines, uneven skin tone, rough skin texture and a dull complexion.
Learn more on the blog: How to Use Glycolic Acid in Your Skin Care Regimen
Shake well and dispense product into hands. Apply an even, pea-sized layer over entire face and neck avoiding the eye area. Precondition skin by limiting initial use to once every other evening. After one week, increase to every evening, or as advised by a skin care professional. Store product in a cool, dark place. This product contains an alpha hydroxy acid (AHA) that may increase your skin’s sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing and limit sun exposure while using this product and for a week afterwards.
What is the recommended use of Glycolic 10 Renew Overnight with retinol?
Remember to #GLOWSLOW. Using Glycolic 10 Renew Overnight alongside retinol products should be done under the guidance of a skin care professional, as certain precautions should be taken. It is recommended to use on alternate nights and not apply both on the same evening.
- If a patient is using retinol, they should introduce Glycolic 10 slowly by limiting initial use to 1–2 nights a week and increasing use gradually to allow the skin to acclimate.
- If a patient is using Glycolic 10 Renew Overnight and wants to introduce retinol, discontinue use until skin is acclimated to retinol and then apply 1–2 nights a week initially, increasing frequency slowly.
Both products may increase skin’s sensitivity to the sun and particularly the possibility of sunburn. Use a broad spectrum sunscreen, wear protective clothing and limit sun exposure while using these products. If irritation occurs, decrease frequency of application of one or both products.
Aging Skin: Fine Lines and Wrinkles
Application Area: Face, Neck
Ideal for these Concerns: Acne, Aging Skin, Free Radical Damage, Hyperpigmentation, Large Pores, Sun Damage
Hyperpigmentation: Dark Spots
Ingredient: Alpha Hydroxy Acids, Antioxidants, Dimethicone, Glycolic Acid, Jojoba, Salicylic Acid, Vitamin E
Preferences: Fragrance-Free, Non-Comedogenic, Paraben-Free, Phthalate-Free
Skin Care: Skin Care Treatments
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Aqua/Water, Glycolic Acid, Dicaprylyl Carbonate, Dimethicone, Sodium Hydroxide, Butylene Glycol, Propanediol, Glycerin, Phytic Acid, Cetyl PEG/PPG-10/1 Dimethicone, Aluminum Starch Octenylsuccinate, Nylon-12, Poly-glyceryl-4 Isostearate, Magnesium Sulfate, Jojoba Esters, Phenoxyethanol, Helianthus Annuus Seed Cera/Sunflower Seed Wax, Caprylyl Glycol, Disodium EDTA, Salicylic Acid, Acacia Decurrens Flower Cera/Accia Decurrens Flower Wax, Polyglycerin-3, Tocopherol, Pentaerythrityl tetra-di-t-butyl Hydroxyhydrocinnamate.
- Correct
- SkinCeuticals
- 1.7 fl. oz
Frequently Bought Together



Total Price: $129.00
Add both to cart
SkinCeuticals Glycolic 10 Renew Overnight (1.7 fl. oz.)
A night cream made with 10% glycolic acid to improve the appearance of skin tone and texture.
Earn 450 reward points when purchasing this product as a rewards member*
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Free delivery
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You control the frequency
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$90.00

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4 installments of $22.50 with Klarna Learn more
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4 installments of $22.50 with afterpay Learn more
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Formulated with 10% glycolic acid, SkinCeuticals' Glycolic 10 Renew Overnight is clinically proven* to promote a brighter, clearer-looking complexion. This powerful face cream is complete with two-percent phytic acid, natural oils and botanicals that promote skin clarity and deep hydration.
Key Ingredients:
- 10% Glycolic Free Acid Value: derived from sugar cane, this powerful fruit acid helps stimulate skin’s natural exfoliation process and minimizes the buildup of dead skin cells, resulting in improvement in the appearance of skin texture and tone.
- 2% Phytic Acid: naturally present in legumes and seeds, this potent ingredient provides dual-action exfoliation and skin brightening effects. It helps to inhibit the impact of skin aggressors that can cause dullness, promoting skin clarity and glow.
- 1% Soothing Complex: featuring a combination of natural oils and botanicals, including jojoba and sunflower seed, this wax forms a protective, breathable layer on skin to help lock in hydration and provide comfort.
Key Benefits:
- Tested tolerable for nightly use
- Accelerates cellular turnover and refines skin texture
- Alcohol-, oil-, fragrance- and dye-free
Clinical Studies:
In an 8-week clinical study, Glycolic 10 Renew Overnight significantly improved the appearance of key markers of glowing skin*:
- 36% average improvement in radiance
- 37% average improvement in skin texture
- 19% average improvement in skin tone
*An 8-week, single-center, clinical study was conducted on 52 females, ages 35-64, with global fine lines, uneven skin tone, rough skin texture and a dull complexion.
Learn more on the blog: How to Use Glycolic Acid in Your Skin Care Regimen
Shake well and dispense product into hands. Apply an even, pea-sized layer over entire face and neck avoiding the eye area. Precondition skin by limiting initial use to once every other evening. After one week, increase to every evening, or as advised by a skin care professional. Store product in a cool, dark place. This product contains an alpha hydroxy acid (AHA) that may increase your skin’s sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing and limit sun exposure while using this product and for a week afterwards.
What is the recommended use of Glycolic 10 Renew Overnight with retinol?
Remember to #GLOWSLOW. Using Glycolic 10 Renew Overnight alongside retinol products should be done under the guidance of a skin care professional, as certain precautions should be taken. It is recommended to use on alternate nights and not apply both on the same evening.
- If a patient is using retinol, they should introduce Glycolic 10 slowly by limiting initial use to 1–2 nights a week and increasing use gradually to allow the skin to acclimate.
- If a patient is using Glycolic 10 Renew Overnight and wants to introduce retinol, discontinue use until skin is acclimated to retinol and then apply 1–2 nights a week initially, increasing frequency slowly.
Both products may increase skin’s sensitivity to the sun and particularly the possibility of sunburn. Use a broad spectrum sunscreen, wear protective clothing and limit sun exposure while using these products. If irritation occurs, decrease frequency of application of one or both products.
Aging Skin: Fine Lines and Wrinkles
Application Area: Face, Neck
Ideal for these Concerns: Acne, Aging Skin, Free Radical Damage, Hyperpigmentation, Large Pores, Sun Damage
Hyperpigmentation: Dark Spots
Ingredient: Alpha Hydroxy Acids, Antioxidants, Dimethicone, Glycolic Acid, Jojoba, Salicylic Acid, Vitamin E
Preferences: Fragrance-Free, Non-Comedogenic, Paraben-Free, Phthalate-Free
Skin Care: Skin Care Treatments
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Aqua/Water, Glycolic Acid, Dicaprylyl Carbonate, Dimethicone, Sodium Hydroxide, Butylene Glycol, Propanediol, Glycerin, Phytic Acid, Cetyl PEG/PPG-10/1 Dimethicone, Aluminum Starch Octenylsuccinate, Nylon-12, Poly-glyceryl-4 Isostearate, Magnesium Sulfate, Jojoba Esters, Phenoxyethanol, Helianthus Annuus Seed Cera/Sunflower Seed Wax, Caprylyl Glycol, Disodium EDTA, Salicylic Acid, Acacia Decurrens Flower Cera/Accia Decurrens Flower Wax, Polyglycerin-3, Tocopherol, Pentaerythrityl tetra-di-t-butyl Hydroxyhydrocinnamate.
- Correct
- SkinCeuticals
- 1.7 fl. oz
Frequently Bought Together



Total Price: $129.00
Add both to cart
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
Reward members earn 50 points for every review written on verified purchases.
A great overnight product
I notice a difference each morning after using this product. My skin looks smoother and has a glow. I alternate nights with retinol.
Report this reviewNight time must have
Glycolic renew is so effective, you don’t need to use every night. I use it every other night, sometimes less, and I wake up to clearer brighter skin every time!
Report this reviewSkinCeuticals Glycolic 10 Renew Overnight
Love this product and use it on the nights that I do not use Retinol...works as described
Report this reviewdoes what it claims
So the only reason I am giving this 4/5 stars is because when I first started using it, I was on hormonal birth control, and using this broke me out in acne around my chin more than usual. I almost swore off of it, but after going off of the hormonal BC and the inevitable purging that happened consequently, I decided to give this another try, since my skin was now totally different. The reaction was like night and day. Without the BC getting in the way, this overnight treatment does what it says it will. It helps to even out my red blotches and help fade old acne scars. My skin looks brighter, younger and more evenly toned in the morning. I will add that it’s not heavily moisturizing - not drying, but if you need extra moisture, I would layer something hydrating on top.
Report this reviewExcellent product
I really see a difference in my skin after using about 6 weeks. It is drying but if skin cycle and use every 4 days it helps that.
Report this reviewGreat!
I am really liking this product for my face! I'm using it on off days from SkinCeuticals Retinol and I feel like its helping to keep my skin turning over from looking so dried out from the retinol. It's also dead winter and I live in the North, 54 y/o so I can definitely see a difference using this versus last year I was way more dry looking. I will say, my neck doesn't love this product, slight irritation, so I'm using a different product on the neck (SkinCeuticals Retexturing Activator). Overall I will purchase this one again!
Report this reviewHoly Grail Glycolic Cream
I have had this in my favorites for a bit waiting for it to come back in stock so I could give it a try and am so glad I did. My daughter and I both have incorporated this into our nightly routine. It has helped clear up some residual acne and acne marks on her skin . My skin is looking fresh, bright and renewed. You have to shake up the cream before application. I use a pea size and it’s enough to cover my whole face. It’s got a little oily texture but goes away once you rub it in all the way. Once arrived my skin feels smooth. Been using every other night with no irritation or sensitivity.
Report this reviewFantastic Product
I love this stuff. So glad it is back in stock. When I use this I wake up feeling like I’ve just had a facial. Highly recommend!
Report this reviewSkinCeuticals Glycolic 10 Renew Overnight
Wonderful overnight treatment that really works! I find using it three nights a week makes a huge difference …..softer texture and more radiance.
Report this review