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SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)
A retinol-based, night lotion for first-time users of all skin types.
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4 installments of $16.00 with Klarna Learn more
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4 installments of $16.00 with afterpay Learn more
SkinMedica's Age Defense Retinol Complex .25 is formulated to renew the skin's tone and texture without irritating the skin. Retinol helps combat the signs of premature aging while magnolia bark extract soothes inflammation. Ideal for use twice a week to build tolerance to formula.
Key Ingredients:
- Retinol: helps boost collagen production and cell turnover to reduce the appearance of fine lines and deep wrinkles
- PhytoShield™ Complex: an antioxidant complex, enhancing skin texture and minimizing irritation
Key Benefits:
- Enhances skin tone and texture
- Boosts more resilient skin
- Diminishes appearance of fine lines and coarse wrinkles
Apply in the evening after cleansing and toning and before applying your moisturizer. If a retinol product has never been used before, begin twice a week 2-3 days apart, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated. Apply to the entire face. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
Caution: Do not use if you are pregnant, lactating or planning to become pregnant. Mild redness, peeling and irritation are expected when using this product. Use daily sun protection with SPF 30 or higher and limit sun exposure while using this product and for a week following discontinuation.
Aging Skin: Fine Lines and Wrinkles
Application Area: Decollete, Face, Neck
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Ingredient: Antioxidants, Ceramides, Essential Oils, Herbal Extracts, Niacinamide, Peptides, Retinol, Squalane Oil, Vitamin A, Vitamin E
Moisturizers: Night Cream
Preferences: Clean, Paraben-Free, Phthalate-Free, Sulfate-Free
Skin Care: Moisturizers
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water/Aqua/Eau, Cetyl Ethylhexanoate, Glycine Soja Oil, Caprylic/Capric Triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl Acetate, Oryza Sativa Bran Cera, Glycerin, Polysorbate 20, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
- Retinol
- SkinMedica
SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)
A retinol-based, night lotion for first-time users of all skin types.
Earn 320 reward points when purchasing this product as a rewards member*
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Free delivery after your first order
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You control the frequency
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No commitment. Cancel or delay
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Payment will be taken every month. months.
$64.00

$130 SkinMedica Gift

Usually despatched within 5 working days.
-
4 installments of $16.00 with Klarna Learn more
-
4 installments of $16.00 with afterpay Learn more
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SkinMedica's Age Defense Retinol Complex .25 is formulated to renew the skin's tone and texture without irritating the skin. Retinol helps combat the signs of premature aging while magnolia bark extract soothes inflammation. Ideal for use twice a week to build tolerance to formula.
Key Ingredients:
- Retinol: helps boost collagen production and cell turnover to reduce the appearance of fine lines and deep wrinkles
- PhytoShield™ Complex: an antioxidant complex, enhancing skin texture and minimizing irritation
Key Benefits:
- Enhances skin tone and texture
- Boosts more resilient skin
- Diminishes appearance of fine lines and coarse wrinkles
Apply in the evening after cleansing and toning and before applying your moisturizer. If a retinol product has never been used before, begin twice a week 2-3 days apart, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated. Apply to the entire face. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
Caution: Do not use if you are pregnant, lactating or planning to become pregnant. Mild redness, peeling and irritation are expected when using this product. Use daily sun protection with SPF 30 or higher and limit sun exposure while using this product and for a week following discontinuation.
Aging Skin: Fine Lines and Wrinkles
Application Area: Decollete, Face, Neck
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Ingredient: Antioxidants, Ceramides, Essential Oils, Herbal Extracts, Niacinamide, Peptides, Retinol, Squalane Oil, Vitamin A, Vitamin E
Moisturizers: Night Cream
Preferences: Clean, Paraben-Free, Phthalate-Free, Sulfate-Free
Skin Care: Moisturizers
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water/Aqua/Eau, Cetyl Ethylhexanoate, Glycine Soja Oil, Caprylic/Capric Triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl Acetate, Oryza Sativa Bran Cera, Glycerin, Polysorbate 20, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
- Retinol
- SkinMedica
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
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You need this
This retinol has been a game changer. The 0.25 concentration is perfect and doesn’t irritate my skin. My skin looks younger since I’ve started using it
Report this reviewGood Retinol
Very mild retinol for beginners. Did not cause irritation or dryness.
Report this reviewRetinol
I have been using this for 3 months and have not seen any difference. I’m in my twenties and i have a few acne scars on my face nothing serious. Spots have not faded at all. Not worth the price.
Report this reviewDon’t waste your money
I’ve been using the entire line for over 8 weeks and have seen zero improvement. The Ordinary was better
Report this reviewLove this retinol!
Love this retinol so far! It is gentle enough that it doesn’t irritate my sensitive skin. I’ve been using it for about 3 weeks now and I haven’t noticed any peeling, flaking, or burning. I have noticed a tiny bit of redness, but I’ve heard and read that is to be expected when using retinol anyways. Overall, I’m super happy I found this retinol to start out with! Will keep using the SkinMedica retinols for sure!
Report this reviewSensitive Skin
This is very nice for those of us with sensitive skin or if you’re trying to work your way up to something stronger. This brand has continued to amaze me, I’m trying to finish up some other products so I can try more of this skincare out. Their H5 hydration is really nice and I’ve been obsessed with Skinceuticles HA intensifier, so this brand may be changing my mind on products.
Report this reviewFlowing feel
Feels nice and smooth. Flows on evenly. Not harsh, no burning feel. I would buy it again
Report this reviewAlways buy this
I love this retinol. I can’t tolerate the higher levels, so the 0.25 is perfect. I use it every night and have noticed a huge difference in my skin. When I started using it, my skin was dry and a little flaky, but now my skin has adjusted well to the product
Report this reviewWorth it!
This has become a staple in my nighttime routine. It has changed my skin and helps me look younger. At first, I had some dryness while using it, so I only applied it twice a week and increased as my skin became used to it.
Report this review