Added to your cart
SkinMedica Age Defense Retinol Complex 0.5 (1 fl. oz.)
A retinol-based, night lotion formulated for retinol users.
-
4 installments of $20.00 with Klarna Learn more
-
4 installments of $20.00 with afterpay Learn more
SkinMedica's Age Defense Retinol Complex 0.5 enhances the skin's texture to promote a brighter, more youthful complexion. Formulated for skin tolerant to retinol treatments, it stimulates collagen production and enhances faster cell renewal to minimize the appearance of fine lines and wrinkles. Algae extract ensures skin is soft, hydrated and protected against free-radical damage.
Key Ingredients:
- Retinol: smooths and refines skin's texture and enhances radiance
- PhytoShield™ Complex: an antioxidant complex, enhances skin texture and minimizes irritation
Key Benefits:
- Enhances skin tone, texture, and resiliency
- Diminishes appearance of fine lines and coarse wrinkles
- Appropriate for all skin types pre-conditioned by using Retinol Complex 0.25 or another retinoid product
Apply a single pump to face in the evening. If you have never used a retinol product before, begin by limiting use to twice a week, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated. Mild redness, peeling and irritation is expected when using this product. Use daily sun protection with SPF 20 or higher during use of this product. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
CAUTION: Do not use if you are pregnant, lactating or planning to become pregnant.
Aging Skin: Fine Lines and Wrinkles, Loss of Firmness
Application Area: Decollete, Face, Neck
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Ingredient: Antioxidants, Ceramides, Essential Oils, Herbal Extracts, Niacinamide, Peptides, Retinol, Squalane Oil, Vitamin A, Vitamin E
Moisturizers: Night Cream
Preferences: Clean, Paraben-Free, Phthalate-Free, Sulfate-Free
Skin Care: Moisturizers
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water/Aqua/Eau, Cetyl Ethylhexanoate, Glycine Soja Oil, Caprylic/Capric Triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl Acetate, Oryza Sativa Bran Cera, Glycerin, Polysorbate 20, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
- Retinol
- SkinMedica
SkinMedica Age Defense Retinol Complex 0.5 (1 fl. oz.)
A retinol-based, night lotion formulated for retinol users.
Earn 400 reward points when purchasing this product as a rewards member*
-
-
Free delivery after your first order
-
You control the frequency
-
No commitment. Cancel or delay
-
Payment will be taken every month. months.
$80.00

$25 SkinMedica Gift


Medik8 Crystal Retinal 3 Serum 30ml

$14 Medik8 Gift

Neocutis LUMIÈRE® FIRM Illuminating Tightening Eye Cream (0.5 fl. oz.)

$196 Neocutis Gift
In stock
-
4 installments of $20.00 with Klarna Learn more
-
4 installments of $20.00 with afterpay Learn more
Delivery & Returns
Live Chat
Average connection time 25 secs
Average connection time 25 secs
SkinMedica's Age Defense Retinol Complex 0.5 enhances the skin's texture to promote a brighter, more youthful complexion. Formulated for skin tolerant to retinol treatments, it stimulates collagen production and enhances faster cell renewal to minimize the appearance of fine lines and wrinkles. Algae extract ensures skin is soft, hydrated and protected against free-radical damage.
Key Ingredients:
- Retinol: smooths and refines skin's texture and enhances radiance
- PhytoShield™ Complex: an antioxidant complex, enhances skin texture and minimizes irritation
Key Benefits:
- Enhances skin tone, texture, and resiliency
- Diminishes appearance of fine lines and coarse wrinkles
- Appropriate for all skin types pre-conditioned by using Retinol Complex 0.25 or another retinoid product
Apply a single pump to face in the evening. If you have never used a retinol product before, begin by limiting use to twice a week, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated. Mild redness, peeling and irritation is expected when using this product. Use daily sun protection with SPF 20 or higher during use of this product. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
CAUTION: Do not use if you are pregnant, lactating or planning to become pregnant.
Aging Skin: Fine Lines and Wrinkles, Loss of Firmness
Application Area: Decollete, Face, Neck
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Ingredient: Antioxidants, Ceramides, Essential Oils, Herbal Extracts, Niacinamide, Peptides, Retinol, Squalane Oil, Vitamin A, Vitamin E
Moisturizers: Night Cream
Preferences: Clean, Paraben-Free, Phthalate-Free, Sulfate-Free
Skin Care: Moisturizers
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water/Aqua/Eau, Cetyl Ethylhexanoate, Glycine Soja Oil, Caprylic/Capric Triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl Acetate, Oryza Sativa Bran Cera, Glycerin, Polysorbate 20, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
- Retinol
- SkinMedica
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
Reward members earn 50 points for every review written on verified purchases.
Skin Medica Retinol
I’ve been using Skin Medica Retinol for years. Love the feel and I think it helps with fine lines and even reduces pore size. I bounce from .25 to .50 for times of skin sensitivity.
Was this review helpful to you?
Fave Retinol
I've tried a few retinol brands, but Skinmedica is my fave! I like that they have the different strengths, & it doesn't seem harsh on my skin.
Was this review helpful to you?
My go to retinol
I love this retinol! My skin tends to be sensitive, dry, and somewhat dehydrated and I find this product doesn't dry me out like many other retinol serums. In fact it's actually somewhat hydrating!
Was this review helpful to you?
Age defense retinol
I have been using for years. I layer over TNS serum in my night time routine. I skip a couple of nights and use AHA/BHA exfoliating cleanser.
Was this review helpful to you?
Two thumbs up
I used to use glycolic acid to exfoliate my skin, and it did work well, but this product is even better. I don't have to use it as often and it just seems more effective.
Was this review helpful to you?
Retinol
I agree with other users. A little amount goes a long way. Let your skin dry completely after washing before applying. Find a good moisturizer and SPF. It’s one of the best on the market.
Was this review helpful to you?
Good
Good quality product and does his job. Isn’t too harsh when used a few nights a week in combination with other products.
Was this review helpful to you?
Gentle Retinol
Recently upgraded from Skinceuticals .3 to this, and am using it every night for about.a week. It's been a gentle enough so far that I've had no redness or flaking. I can't say that would be the case if your skin was not used to a lower dosage, but it's been nice to not go through an initial drying period in the first week. Skin looks fresher since upgrading as well, but am noticing some purging.
Was this review helpful to you?
Great for aging skin
I have been using retinols for several years. Skin Medica is my favorite brand
Was this review helpful to you?
Holy grail!
Love love love!! It’s time released and doesn’t dry out my skin.
Was this review helpful to you?
Other customers bought:
-
SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)
SkinMedica Dermal Repair Cream 0.25 oz (Worth $25.00) Value $25.00$25 SkinMedica Gift
Receive a SkinMedica Dermal Repair Cream 0.25 oz ($25 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.SHOP NOW$64.00 -
SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)
SkinMedica Dermal Repair Cream 0.25 oz (Worth $25.00) Value $25.00$25 SkinMedica Gift
Receive a SkinMedica Dermal Repair Cream 0.25 oz ($25 value) when you spend $175 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.SHOP NOW$96.00 -
Dr. Dennis Gross Skincare Alpha Beta Exfoliating Body Treatment 8 count
Dr Dennis Gross Skincare Alpha Beta Universal Daily Peel 3-Applications 2.2ml (Worth $13.00) Value $13.00$13 Dr Dennis Gross Gift
Receive a Dr Dennis Gross Alpha Beta Universal Daily Peel 2.2ml when you spend $80 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.SHOP NOW$60.00