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SkinMedica Age Defense Retinol Complex 0.5 (1 fl. oz.)
A retinol-based, night lotion formulated for retinol users.
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4 installments of $20.00 with Klarna Learn more
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4 installments of $20.00 with afterpay Learn more
SkinMedica's Age Defense Retinol Complex 0.5 enhances the skin's texture to promote a brighter, more youthful complexion. Formulated for skin tolerant to retinol treatments, it stimulates collagen production and enhances faster cell renewal to minimize the appearance of fine lines and wrinkles. Algae extract ensures skin is soft, hydrated and protected against free-radical damage.
Key Ingredients:
- Retinol: smooths and refines skin's texture and enhances radiance
- PhytoShield™ Complex: an antioxidant complex, enhances skin texture and minimizes irritation
Key Benefits:
- Enhances skin tone, texture, and resiliency
- Diminishes appearance of fine lines and coarse wrinkles
- Appropriate for all skin types pre-conditioned by using Retinol Complex 0.25 or another retinoid product
Apply a single pump to face in the evening. If you have never used a retinol product before, begin by limiting use to twice a week, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated. Mild redness, peeling and irritation is expected when using this product. Use daily sun protection with SPF 20 or higher during use of this product. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
CAUTION: Do not use if you are pregnant, lactating or planning to become pregnant.
Aging Skin: Fine Lines and Wrinkles, Loss of Firmness
Application Area: Decollete, Face, Neck
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Ingredient: Antioxidants, Ceramides, Essential Oils, Herbal Extracts, Niacinamide, Peptides, Retinol, Squalane Oil, Vitamin A, Vitamin E
Moisturizers: Night Cream
Preferences: Clean, Paraben-Free, Phthalate-Free, Sulfate-Free
Skin Care: Moisturizers
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water/Aqua/Eau, Cetyl Ethylhexanoate, Glycine Soja Oil, Caprylic/Capric Triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl Acetate, Oryza Sativa Bran Cera, Glycerin, Polysorbate 20, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
- Retinol
- SkinMedica
SkinMedica Age Defense Retinol Complex 0.5 (1 fl. oz.)
A retinol-based, night lotion formulated for retinol users.
Earn 400 reward points when purchasing this product as a rewards member*
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Free delivery after your first order
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You control the frequency
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No commitment. Cancel or delay
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Payment will be taken every month. months.
$80.00

$66 Gift



Chantecaille Future Skin - Hazel

$149 Chantecaille Gift
In stock
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4 installments of $20.00 with Klarna Learn more
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4 installments of $20.00 with afterpay Learn more
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SkinMedica's Age Defense Retinol Complex 0.5 enhances the skin's texture to promote a brighter, more youthful complexion. Formulated for skin tolerant to retinol treatments, it stimulates collagen production and enhances faster cell renewal to minimize the appearance of fine lines and wrinkles. Algae extract ensures skin is soft, hydrated and protected against free-radical damage.
Key Ingredients:
- Retinol: smooths and refines skin's texture and enhances radiance
- PhytoShield™ Complex: an antioxidant complex, enhances skin texture and minimizes irritation
Key Benefits:
- Enhances skin tone, texture, and resiliency
- Diminishes appearance of fine lines and coarse wrinkles
- Appropriate for all skin types pre-conditioned by using Retinol Complex 0.25 or another retinoid product
Apply a single pump to face in the evening. If you have never used a retinol product before, begin by limiting use to twice a week, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated. Mild redness, peeling and irritation is expected when using this product. Use daily sun protection with SPF 20 or higher during use of this product. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
CAUTION: Do not use if you are pregnant, lactating or planning to become pregnant.
Aging Skin: Fine Lines and Wrinkles, Loss of Firmness
Application Area: Decollete, Face, Neck
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Ingredient: Antioxidants, Ceramides, Essential Oils, Herbal Extracts, Niacinamide, Peptides, Retinol, Squalane Oil, Vitamin A, Vitamin E
Moisturizers: Night Cream
Preferences: Clean, Paraben-Free, Phthalate-Free, Sulfate-Free
Skin Care: Moisturizers
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water/Aqua/Eau, Cetyl Ethylhexanoate, Glycine Soja Oil, Caprylic/Capric Triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl Acetate, Oryza Sativa Bran Cera, Glycerin, Polysorbate 20, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
- Retinol
- SkinMedica
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
Reward members earn 50 points for every review written on verified purchases.
Gentle Retinol
Recently upgraded from Skinceuticals .3 to this, and am using it every night for about.a week. It's been a gentle enough so far that I've had no redness or flaking. I can't say that would be the case if your skin was not used to a lower dosage, but it's been nice to not go through an initial drying period in the first week. Skin looks fresher since upgrading as well, but am noticing some purging.
Report this reviewGreat for aging skin
I have been using retinols for several years. Skin Medica is my favorite brand
Report this reviewEnhances skin tone
I have been using this for about 10 years . My dermatologist recommended it . It is a must for your skin care routine . It evens out tone and texture. If you are new to retinol start with the .25 and work your way up . I tried 1.0 my skin peeled a lot and got red so for me the .5 is perfect
Report this reviewGreat Retinol
I’ve used this retinol for about 7 years now. I only use it every other day because I have sensitive skin. It’s kept me feeling young.
Report this reviewRevisiting a favorite
After having microneedling done, my skin was entirely too sensitive to go back to 1% Tret. I forgot how much I loved this product - gentle but so effective!
Report this reviewLoving it so far
I bought my first SkinMedica retinol in the 0.25 back in December, tolerated it well, and decided to move up to the 0.5 for the next bottle. The 0.25 bottle lasted me nearly 3 months, so I'm hoping the 0.5 lasts just as long! I personally have not experienced any irritation from either bottle! My skin is on the drier side and is fairly sensitive/somewhat acne-prone, and my skin seems to love this retinol. I already am noticing much quicker skin turnover and feel like it has helped reduce scarring noticeably already within the first week of use. Wish it weren't as pricey but still very happy!
Report this reviewLOVE
It took my skin the 2 weeks or so to get used to the retinol, but I feel like I have results after a few months! Getting compliments on my skin like never before!
Report this reviewRetinol
I recently upped to this product from the .25 version. It is definitely drying but works well when paired with a thicker moisturizer.
Report this review