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SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)
A retinol-based treatment to improve the skin's tone and texture.
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4 installments of $24.00 with Klarna Learn more
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4 installments of $24.00 with afterpay Learn more
SkinMedica's Age Defense Retinol Complex 1.0 enhances the skin's appearance to promote a smoother, rejuvenated complexion. Formulated for skin types pre-conditioned to retinol treatments, it minimizes the appearance of age spots and wrinkles. It also improves elasticity and works effectively to visibly reduce acne scars. With continued use, faster cell renewal is encouraged.
Key Ingredients:
- Retinol: smooths and refines skin's texture and enhances radiance
- PhytoShield™ Complex: an antioxidant complex, enhances skin texture and minimizes irritation
Key Benefits:
- Diminishes appearance of fine lines and coarse wrinkles
- Enhances skin tone and texture
- Ideal for all skin types
Apply a single pump to face in the evening. If you have never used a retinol product before, begin by limiting use to twice a week, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated. Mild redness, peeling and irritation is expected when using this product. Use daily sun protection with SPF 20 or higher during use of this product. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
CAUTION: Do not use if you are pregnant, lactating or planning to become pregnant.
Aging Skin: Fine Lines and Wrinkles
Application Area: Decollete, Face, Neck
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Ingredient: Antioxidants, Ceramides, Essential Oils, Herbal Extracts, Niacinamide, Peptides, Retinol, Squalane Oil, Vitamin A, Vitamin E
Moisturizers: Night Cream
Preferences: Clean, Paraben-Free, Phthalate-Free, Sulfate-Free
Skin Care: Moisturizers
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water/Aqua/Eau, Cetyl Ethylhexanoate, Glycine Soja Oil, Caprylic/Capric Triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl Acetate, Oryza Sativa Bran Cera, Glycerin, Polysorbate 20, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
- Retinol
- SkinMedica
- 30ml
Frequently Bought Together



Total Price: $202.00
Add both to cart
SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)
A retinol-based treatment to improve the skin's tone and texture.
Earn 480 reward points when purchasing this product as a rewards member*
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Free delivery after your first order
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You control the frequency
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No commitment. Cancel or delay
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Payment will be taken every month. months.
$96.00

10% off SkinMedica with code SUN + $66 Gift


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Obagi Medical Professional-C Serum 15% (1 fl. oz.)
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In stock
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4 installments of $24.00 with Klarna Learn more
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4 installments of $24.00 with afterpay Learn more
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SkinMedica's Age Defense Retinol Complex 1.0 enhances the skin's appearance to promote a smoother, rejuvenated complexion. Formulated for skin types pre-conditioned to retinol treatments, it minimizes the appearance of age spots and wrinkles. It also improves elasticity and works effectively to visibly reduce acne scars. With continued use, faster cell renewal is encouraged.
Key Ingredients:
- Retinol: smooths and refines skin's texture and enhances radiance
- PhytoShield™ Complex: an antioxidant complex, enhances skin texture and minimizes irritation
Key Benefits:
- Diminishes appearance of fine lines and coarse wrinkles
- Enhances skin tone and texture
- Ideal for all skin types
Apply a single pump to face in the evening. If you have never used a retinol product before, begin by limiting use to twice a week, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated. Mild redness, peeling and irritation is expected when using this product. Use daily sun protection with SPF 20 or higher during use of this product. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
CAUTION: Do not use if you are pregnant, lactating or planning to become pregnant.
Aging Skin: Fine Lines and Wrinkles
Application Area: Decollete, Face, Neck
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Ingredient: Antioxidants, Ceramides, Essential Oils, Herbal Extracts, Niacinamide, Peptides, Retinol, Squalane Oil, Vitamin A, Vitamin E
Moisturizers: Night Cream
Preferences: Clean, Paraben-Free, Phthalate-Free, Sulfate-Free
Skin Care: Moisturizers
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water/Aqua/Eau, Cetyl Ethylhexanoate, Glycine Soja Oil, Caprylic/Capric Triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl Acetate, Oryza Sativa Bran Cera, Glycerin, Polysorbate 20, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
- Retinol
- SkinMedica
- 30ml
Frequently Bought Together



Total Price: $202.00
Add both to cart
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
Reward members earn 50 points for every review written on verified purchases.
Solid product
High strength retinol. I have high skin tolerance to retinol so I have no skin reaction to this product. Definitely firm up & clears up skin. Though it does not have a wow factor in am like the glow I wake up with after using Sunday Riley high dose retinol. I trust skin medical products to be top of the line effective.
Report this reviewWorks on my neck
I had to go back up to 1.0 because my neck has gotten so bad. I think this is helping the ugly sagging that has happened as much as it can be helped without surgery.
Report this reviewBest of the best
This is the best retinol off the counter compared to the prescribed retinol from my dermatologist. I've been ordering this retinol on repeat for the past 3 years, and will be be part of my every night skincare routine.
Report this reviewSkinmedica Age defense retinol
Amazing! Makes age spots or brown spots disappear! Nothing better than this!
Report this reviewvery good
I alrealdy used retinol for 4 years, retinol can make face diminishes appearance of fine lines and coarse wrinkles. I alawys used ZO SKIN, i love it, but when i want change the feeling, i will choose this one take turns.
Report this reviewGreat retinol just go slow.
This had done wonders for my acne prone skin. I was struggling with sebacous filaments on my nose, some large pores on my cheeks and re-curring breakouts around my mouth and temples. After 3 weeks my breakouts have stopped almost completely. I get an occasional small pimple but they are much more manageable. My advice is to start only after you have purchased a quality face sucncreen and moisturizer because you have to use suncreen every day while using this product. EVERYDAY - even if its cloudy. I learned the hard way and got a burn on my face after the first day because I thought it was cloudy enough I could skip the spf. NOPE! Start by applying once a night every 3 days for the first few weeks then slowly build up the frequency from there. I stick with the whole skin medica line and use this with their suncreen and their ultra sheer moisturizer. I apply moisturizer 10 minutes after my retinol at night and then apply the moizturizer again after I wash my face in the morning and then apply the SM suncreen ontop of the moisturizer. This helps keep the dryness and redness at bay while using this high concentration of retinol. This has honestly helped my skin so much. I have started to not have to use foundation daily which is pretty close to a miracle for me. Took at least 1 month for my skin to start to show the benefits but I am glad I waited and stuck with the routine. I am 31 and wish I started retinol long ago. I previousy used Sunday Riley .625 but found it was not as effective as the SM 1.0. Also avoid going under the eyes! I also reccomend if you use eye cream put it on before your retinol so you dont accidently push the retinol under your eye which can happen if you apply your eye cream after.
Report this reviewStill working though this purchase
Start slow if you’ve used a lower strength retinol if you have sensitive skin. This is still very drying for me and has taken some time for my skin to adjust. I plan to stick with it. I’m using once a week this month and plan to increase frequency in the second month to twice a week.
Report this reviewDecent
Good product w strong retinol effect. I have tried and been equally impressed w lesser costing retinols but this one does feel nicer when applying to the face and seems easier to get an even spread over my face too.
Report this reviewSkin Medica Age Defense Retinol 1.0
I have been using Skin Medica Age Defense Retinol for 18 years now. My skin is unbelievable because of this product. I always order it from Dermstore.
Report this review