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SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)
A retinol-based treatment to improve the skin's tone and texture.
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4 installments of $24.00 with Klarna Learn more
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4 installments of $24.00 with afterpay Learn more
SkinMedica's Age Defense Retinol Complex 1.0 enhances the skin's appearance to promote a smoother, rejuvenated complexion. Formulated for skin types pre-conditioned to retinol treatments, it minimizes the appearance of age spots and wrinkles. It also improves elasticity and works effectively to visibly reduce acne scars. With continued use, faster cell renewal is encouraged.
Key Ingredients:
- Retinol: smooths and refines skin's texture and enhances radiance
- PhytoShield™ Complex: an antioxidant complex, enhances skin texture and minimizes irritation
Key Benefits:
- Diminishes appearance of fine lines and coarse wrinkles
- Enhances skin tone and texture
- Ideal for all skin types
Apply a single pump to face in the evening. If you have never used a retinol product before, begin by limiting use to twice a week, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated. Mild redness, peeling and irritation is expected when using this product. Use daily sun protection with SPF 20 or higher during use of this product. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
CAUTION: Do not use if you are pregnant, lactating or planning to become pregnant.
Aging Skin: Fine Lines and Wrinkles
Application Area: Decollete, Face, Neck
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Ingredient: Antioxidants, Ceramides, Essential Oils, Herbal Extracts, Niacinamide, Peptides, Retinol, Squalane Oil, Vitamin A, Vitamin E
Moisturizers: Night Cream
Preferences: Clean, Paraben-Free, Phthalate-Free, Sulfate-Free
Skin Care: Moisturizers
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water/Aqua/Eau, Cetyl Ethylhexanoate, Glycine Soja Oil, Caprylic/Capric Triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl Acetate, Oryza Sativa Bran Cera, Glycerin, Polysorbate 20, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
- Retinol
- SkinMedica
- 30ml
Frequently Bought Together



Total Price: $202.00
Add both to cart
SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)
A retinol-based treatment to improve the skin's tone and texture.
Earn 480 reward points when purchasing this product as a rewards member*
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Free delivery
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You control the frequency
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No commitment. Cancel or delay
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Payment will be taken every month. months.
$96.00

$130 SkinMedica Gift

Usually despatched within 5 working days.
-
4 installments of $24.00 with Klarna Learn more
-
4 installments of $24.00 with afterpay Learn more
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SkinMedica's Age Defense Retinol Complex 1.0 enhances the skin's appearance to promote a smoother, rejuvenated complexion. Formulated for skin types pre-conditioned to retinol treatments, it minimizes the appearance of age spots and wrinkles. It also improves elasticity and works effectively to visibly reduce acne scars. With continued use, faster cell renewal is encouraged.
Key Ingredients:
- Retinol: smooths and refines skin's texture and enhances radiance
- PhytoShield™ Complex: an antioxidant complex, enhances skin texture and minimizes irritation
Key Benefits:
- Diminishes appearance of fine lines and coarse wrinkles
- Enhances skin tone and texture
- Ideal for all skin types
Apply a single pump to face in the evening. If you have never used a retinol product before, begin by limiting use to twice a week, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated. Mild redness, peeling and irritation is expected when using this product. Use daily sun protection with SPF 20 or higher during use of this product. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
CAUTION: Do not use if you are pregnant, lactating or planning to become pregnant.
Aging Skin: Fine Lines and Wrinkles
Application Area: Decollete, Face, Neck
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Ingredient: Antioxidants, Ceramides, Essential Oils, Herbal Extracts, Niacinamide, Peptides, Retinol, Squalane Oil, Vitamin A, Vitamin E
Moisturizers: Night Cream
Preferences: Clean, Paraben-Free, Phthalate-Free, Sulfate-Free
Skin Care: Moisturizers
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water/Aqua/Eau, Cetyl Ethylhexanoate, Glycine Soja Oil, Caprylic/Capric Triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl Acetate, Oryza Sativa Bran Cera, Glycerin, Polysorbate 20, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
- Retinol
- SkinMedica
- 30ml
Frequently Bought Together



Total Price: $202.00
Add both to cart
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
Reward members earn 50 points for every review written on verified purchases.
Sensitive skin beware
I am giving this 5 stars because I know the product is good, I’ve used the 0.25 and 0.5 for a couple years and finally thought my skin could handle 1.0. It’s been over a month and my skin still can’t handle more than 2 nights a week of use before it starts peeling like crazy. I will continue to use the product because it’s pricey and I’m still hoping my skin adjusts. I will also try the retinol sandwhich approach and see if that helps.
Report this reviewGentle
Most retinols are pretty drying and start to flake your skin at some point, but this might be the most gentle moisturizing retinol at such a high grade that has never done anything to my face.
Report this reviewComplete resurfacing
I couldn't believe what a difference this product made in my skin. Freckles I had had for years were erased. If your skin can tolerate the 1.0, it is a game changer.
Report this reviewRetinol Ready
I have used SkinMedica Age Defense Retinol Complex 1.0 for several years and it has not disappointed! The strength is high which allows very little to go a long way during less frequent applications. I use it once a week on my face, neck and the back of my hands to control age spots, wrinkles and promote collagen production. If magic in a bottle really does exist, this one comes very close to it. The texture is light and it spreads easily allowing for a little to cover large areas. I highly recommend this retinol product because it actually slows down the natural aging process.
Report this reviewAmazing Retinol Cream!
I have worked my way up to this and it has been amazing for my skin. I have never had skin in my whole entire life like I do now. So thankful that I found this product and this brand! THE BEST!
Report this reviewSkinmedica Retinol 1%
This is a fantastic retinol. I have found that it is not as harsh as other retinols of similar price point.
Report this reviewRetinol
I've used this retinol for years! It helps with wrinkles and aging skin! It does not burn or feel harsh! My skin will have a little bit of peeling now and then around the nose area! Then I wait a day to apply it again! But I think because I have used it so long my skin has got through the peeling stage and now I'm glowing!!😊
Report this reviewLove
Love this product. Worked up from their lowest amount to this one and my sensitive skin can handle it. Some peeling to be expecting when increasing the amount of retinol, but that will subside.
Report this review