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SkinMedica TNS Advanced+ Serum (1 oz.)
A powerful anti-aging serum that targets fine lines, deep wrinkles and sagging skin.
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4 installments of $73.75 with Klarna Learn more
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4 installments of $73.75 with afterpay Learn more
SkinMedica's TNS Advanced+ Serum is a skin rejuvenating formula that visibly improves the appearance of coarse wrinkles, fine lines and sagging skin. Powered by TNS®-MR and Renessensce (RSC) Advanced, this combination encourages skin cell renewal and supports collagen and elastin levels revealing a smoother, more radiant and youthful complexion.
Key Ingredients:
- TNS®-MR: This advanced formula acts on multiple levels to help get you to your best results. Next-generation growth factor blend supports healthy skin functions and an innovative peptide complex nourishes your skin.
- Renessensce (RSC) Advanced: This highly active blend of botanicals, marine extracts, and peptides includes french flax seed to support repair functions. Spanish marine extract supports skin’s renewal processes and green microalgae support collagen and elastin levels.
Key Benefits:
- Smooths visible coarse wrinkles and fine lines
- Visibly lifts sagging skin
- Evens the appearance of skin tone and texture
- Visible results start in just 2 weeks, with progressive improvements measured over 24 weeks*
- Colorless and fragrance-free
*Results from a clinical study with 45 male and female subjects, ages 37—70, that received TNS® Advanced+ Serum twice daily for 24 weeks.
AM/PM: Dispense a single pump onto the back of your hand, blend together and apply to the face morning and night. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
Aging Skin: Fine Lines and Wrinkles, Loss of Firmness
Application Area: Face
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Holiday: Gifts for Mom
Preferences: Fragrance-Free
Skin Care: Skin Care Treatments
Skin Care Treatments: Face Serums
Skin Type: Mature Skin, Normal Skin
Water/Aqua/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Trifluoroacetyl Tripeptide-2, Dimer Tripeptide-43, Hydrolyzed Linseed Extract, Vitis Vinifera (Grape) Flower Cell Extract, Pyrus Malus (Apple) Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Dextran, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
- SkinMedica
- 1oz
Frequently Bought Together



Total Price: $479.00
Add both to cart
SkinMedica TNS Advanced+ Serum (1 oz.)
A powerful anti-aging serum that targets fine lines, deep wrinkles and sagging skin.
Earn 1475 reward points when purchasing this product as a rewards member*
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Free delivery after your first order
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You control the frequency
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No commitment. Cancel or delay
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Payment will be taken every month. months.
$295.00

$25 SkinMedica Gift


Olaplex No. 3 Hair Perfector (3.3 fl. oz.)
20% Off With Code HAIR + $120 Gift
In stock
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4 installments of $73.75 with Klarna Learn more
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4 installments of $73.75 with afterpay Learn more
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SkinMedica's TNS Advanced+ Serum is a skin rejuvenating formula that visibly improves the appearance of coarse wrinkles, fine lines and sagging skin. Powered by TNS®-MR and Renessensce (RSC) Advanced, this combination encourages skin cell renewal and supports collagen and elastin levels revealing a smoother, more radiant and youthful complexion.
Key Ingredients:
- TNS®-MR: This advanced formula acts on multiple levels to help get you to your best results. Next-generation growth factor blend supports healthy skin functions and an innovative peptide complex nourishes your skin.
- Renessensce (RSC) Advanced: This highly active blend of botanicals, marine extracts, and peptides includes french flax seed to support repair functions. Spanish marine extract supports skin’s renewal processes and green microalgae support collagen and elastin levels.
Key Benefits:
- Smooths visible coarse wrinkles and fine lines
- Visibly lifts sagging skin
- Evens the appearance of skin tone and texture
- Visible results start in just 2 weeks, with progressive improvements measured over 24 weeks*
- Colorless and fragrance-free
*Results from a clinical study with 45 male and female subjects, ages 37—70, that received TNS® Advanced+ Serum twice daily for 24 weeks.
AM/PM: Dispense a single pump onto the back of your hand, blend together and apply to the face morning and night. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
Aging Skin: Fine Lines and Wrinkles, Loss of Firmness
Application Area: Face
Ideal for these Concerns: Aging Skin, Free Radical Damage, Hyperpigmentation
Holiday: Gifts for Mom
Preferences: Fragrance-Free
Skin Care: Skin Care Treatments
Skin Care Treatments: Face Serums
Skin Type: Mature Skin, Normal Skin
Water/Aqua/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Trifluoroacetyl Tripeptide-2, Dimer Tripeptide-43, Hydrolyzed Linseed Extract, Vitis Vinifera (Grape) Flower Cell Extract, Pyrus Malus (Apple) Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Dextran, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin.
- SkinMedica
- 1oz
Frequently Bought Together



Total Price: $479.00
Add both to cart
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
Reward members earn 50 points for every review written on verified purchases.
TNS Advanced Serum is like magic!
I've been using the serum for about a month now and within one week I noticed how much more plump and smooth my skin looked. My pores are noticeably smaller. I'm so, so happy with this product. It's worth every penny!
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TNS Advances Serum
I love TNS Advanced Serum. I've been using it for years..it leaves my skin smooth and glowing ..and I believe a bit tighter! I trust the Dermstore they carry only authentic products and always have samples of other products to try when your purchase is above a certain amount. There is a rewards system so points go towards my next purchase...and they run periodically sales..I highly recommend the Dermstore for TNSAdvanced serum!
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TNS
I want to say this doesn’t help, but it does. My skin is even, smooth and looks pretty darn good using this serum. It isn’t drying. No strong odor. It leaves skin looking refreshed and glowing.
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Great Feeling
Use this morning & night. Love the way my skin looks & feels!
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Magical
This is THE best product I have used. I have results in my skin texture and fine . My skin has never looked this good!!
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Definitely a worthwhile addition!
I am 63 and have been taking really good care of my skin for at least 15 or 20 years. I started with Clinique repairware and Estee Lauder night repair. When I moved on to dermatologist recommended SkinCeuticals vitamin C I noticed a huge difference. Then I added various drugstore retinols at night. Another big improvement. Just recently I added the TNC serum. Oh my! I use it in the morning before my vitamin C and my moisturizer. Then again at night before my retinol. My skin looks great! Yesterday 2 young cashiers were staring at me and telling me I was cute! and asking me what I use on my skin. Did I use botox (no!). By the way, I had to contact the company to find out the order to apply the serums. They answered with an email and phone call. There should be more information with the TNS serum (my only complaint besides the high price). I am on autoship.
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so many compliments
have been using this for several years now. I am 74. I get so many compliments about my skin. It has to be the TNS!
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Packaging
I would give the product 5 stars except for the packaging. Many of the containers have silver tops that start to shed after a very few uses. Expect little silver flecks on your face that are not easy to get off. Annoying.
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Great Product
I love the way my skin looks after using this. My dermatologist recomended this, SkinMedica is their flagship brand and I didn't like the cost of it, but it gives me good results so I keep using it.
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great for aging skin
I have very sensitive skin which tends to get red and irritated with many serums. Love this - no sensitivity and skin appearance improving
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