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SkinMedica TNS Essential Serum (1 oz.)
An anti-aging facial treatment with a dual formula to boost a more youthful appearance.
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4 installments of $70.25 with Klarna Learn more
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4 installments of $70.25 with afterpay Learn more
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4 installments of $70.25 with sezzle Learn more
SkinMedica's TNS Essential Serum features two active formulas that dispense out of two separate chambers and are blended together into one creating a powerful solution that helps smooth wrinkles and regenerate skin cells for a more youthful appearance. The TNS Recovery Complex® is a protein- and amino acid-rich serum to reduce inflammation and the signs of aging. The APS Corrective Complex is a mixture of anti-aging ingredients, peptides and antioxidants to strengthen sagging skin.
Key Ingredients:
- TNS Recovery Complex® (Human Fibroblast Conditioned Media TNS®) - chamber 1: a physiologically balanced, naturally secreted and stabilized growth factor blend that helps improve the appearance of fine lines, wrinkles, skin tone and texture
- APS Corrective Complex - chamber 2: a blend of peptides, antioxidants and other powerful anti-aging ingredients that help support smoother, firmer skin and prevent free-radical damage
Key Benefits:
- Reduces the appearance of fine lines and wrinkles
- Enhances skin tone and texture
- Two powerful formulas to rejuvenate the skin
- Ideal for all skin types
Learn more on the blog: New to SkinMedica? Here Are 3 Products to Try First According to a Dermatologist.
Apply in the morning and evening after cleansing and toning. Apply to your entire face (neck and chest if desired). Dispense on the back of your hand and blend together before applying to the skin. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
Aging Skin: Fine Lines and Wrinkles, Loss of Firmness
Application Area: Decollete, Face, Neck
Ideal for these Concerns: Aging Skin, Dryness and Dehydration, Free Radical Damage, Hyperpigmentation
Ingredient: Antioxidants, Dimethicone, Green Tea, Hyaluronic Acid, Olive Oil, Peptides, Shea Butter, Vitamin C, Vitamin E
Preferences: Paraben-Free
Skin Care: Skin Care Treatments
Skin Care Treatments: Face Serums
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Human Fibroblast Conditioned Media, Water/Aqua/Eau, Cetyl Ethylhexanoate, Olea Europaea (Olive) Fruit Unsaponifiables, Alpha-Arbutin, Isoceteth-20, Arachidyl Alcohol, Glycerin, Ethoxydiglycol, Butyrospermum Parkii (Shea) Butter, Dimethicone, Tetrahexyldecyl Ascorbate, Dipalmitoyl Hydroxyproline, Palmitoyl Tripeptide-5, Ergothioneine, Hydrolyzed Sericin, Phospholipids, Ubiquinone, Rubus Fruticosus (Blackberry) Leaf Extract, Saccharomyces Ferment Lysate Filtrate, Aminobutyric Acid, Phytosterols, Tocopherol, Tocotrienols, Squalene, Oryza Sativa (Rice) Bran Wax (Oryza Sativa Cera), Sodium Hyaluronate, Tocopheryl Acetate, Camellia Oleifera Leaf Extract, Ethylhexyl Palmitate, Silica Dimethyl Silylate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Behenyl Alcohol, Arachidyl Glucoside, Cetearyl Alcohol, Steareth-10, Steareth-20, Butylene Glycol, Maltodextrin, C12-15 Alkyl Benzoate, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Aminomethyl Propanol, Disodium EDTA, Caprylyl Glycol, Caprylhydroxamic Acid, Ethylhexylglycerin, Phenoxyethanol, Potassium Sorbate, Parfum/Fragrance, Hydroxycitronellal, Linalool, Coumarin, Alpha-Isomethyl Ionone, Geraniol, Isoeugenol.
Frequently Bought Together



Total Price: $465.00
Add both to cart
SkinMedica TNS Essential Serum (1 oz.)
An anti-aging facial treatment with a dual formula to boost a more youthful appearance.
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$281.00

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4 installments of $70.25 with Klarna Learn more
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4 installments of $70.25 with afterpay Learn more
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4 installments of $70.25 with sezzle Learn more
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SkinMedica's TNS Essential Serum features two active formulas that dispense out of two separate chambers and are blended together into one creating a powerful solution that helps smooth wrinkles and regenerate skin cells for a more youthful appearance. The TNS Recovery Complex® is a protein- and amino acid-rich serum to reduce inflammation and the signs of aging. The APS Corrective Complex is a mixture of anti-aging ingredients, peptides and antioxidants to strengthen sagging skin.
Key Ingredients:
- TNS Recovery Complex® (Human Fibroblast Conditioned Media TNS®) - chamber 1: a physiologically balanced, naturally secreted and stabilized growth factor blend that helps improve the appearance of fine lines, wrinkles, skin tone and texture
- APS Corrective Complex - chamber 2: a blend of peptides, antioxidants and other powerful anti-aging ingredients that help support smoother, firmer skin and prevent free-radical damage
Key Benefits:
- Reduces the appearance of fine lines and wrinkles
- Enhances skin tone and texture
- Two powerful formulas to rejuvenate the skin
- Ideal for all skin types
Learn more on the blog: New to SkinMedica? Here Are 3 Products to Try First According to a Dermatologist.
Apply in the morning and evening after cleansing and toning. Apply to your entire face (neck and chest if desired). Dispense on the back of your hand and blend together before applying to the skin. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.
Aging Skin: Fine Lines and Wrinkles, Loss of Firmness
Application Area: Decollete, Face, Neck
Ideal for these Concerns: Aging Skin, Dryness and Dehydration, Free Radical Damage, Hyperpigmentation
Ingredient: Antioxidants, Dimethicone, Green Tea, Hyaluronic Acid, Olive Oil, Peptides, Shea Butter, Vitamin C, Vitamin E
Preferences: Paraben-Free
Skin Care: Skin Care Treatments
Skin Care Treatments: Face Serums
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Human Fibroblast Conditioned Media, Water/Aqua/Eau, Cetyl Ethylhexanoate, Olea Europaea (Olive) Fruit Unsaponifiables, Alpha-Arbutin, Isoceteth-20, Arachidyl Alcohol, Glycerin, Ethoxydiglycol, Butyrospermum Parkii (Shea) Butter, Dimethicone, Tetrahexyldecyl Ascorbate, Dipalmitoyl Hydroxyproline, Palmitoyl Tripeptide-5, Ergothioneine, Hydrolyzed Sericin, Phospholipids, Ubiquinone, Rubus Fruticosus (Blackberry) Leaf Extract, Saccharomyces Ferment Lysate Filtrate, Aminobutyric Acid, Phytosterols, Tocopherol, Tocotrienols, Squalene, Oryza Sativa (Rice) Bran Wax (Oryza Sativa Cera), Sodium Hyaluronate, Tocopheryl Acetate, Camellia Oleifera Leaf Extract, Ethylhexyl Palmitate, Silica Dimethyl Silylate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Behenyl Alcohol, Arachidyl Glucoside, Cetearyl Alcohol, Steareth-10, Steareth-20, Butylene Glycol, Maltodextrin, C12-15 Alkyl Benzoate, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Aminomethyl Propanol, Disodium EDTA, Caprylyl Glycol, Caprylhydroxamic Acid, Ethylhexylglycerin, Phenoxyethanol, Potassium Sorbate, Parfum/Fragrance, Hydroxycitronellal, Linalool, Coumarin, Alpha-Isomethyl Ionone, Geraniol, Isoeugenol.
Frequently Bought Together



Total Price: $465.00
Add both to cart
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
Reward members earn 50 points for every review written on verified purchases.
Worth it!
This product is it! I recommend it to everyone! Everything else is a waste of money, in my experience. I use it twice a day, with or without moisturizer. My dermatologist recommended it to me initially and I’ve used it for years now. You can really see a difference.
Report this reviewLOVE
Love this serum — The OG gold standard for topical growth factors. Some people might not like the smell and prefer SkinMedica”s newer product (TNS Advanced+ serum) which has virtually no smell, but the newer product consistently makes my face dry and peel whereas this product makes my skin supple without unseemly side effects.
Report this reviewAmazing product
While pricey, this product is one of those splurges that is worth the cost. Visible results with consistent use. I use in the morning before putting on sunscreen and then foundation. Diminishes the appearance of fine lines and makes skin look fresh. Suggestions: make a travel-friendly container. This really messes up the contents of my TSA bag by taking up so much room. Also would be helpful to have some sort of indicator on container so user knows when it’s time to reorder.
Report this reviewGreat product
So I loved this! Definitely noticed a difference after some time of daily use. I started using the advanced+ TNS serum though and it’s a game changer !
Report this reviewIt works
Been using it for a year and have seen better skin. It gives a glow that was lacking.
Report this reviewBest Product
I have been using this product for 2 years and it has improved my tone and texture.
Report this reviewYouth in a bottle
Hands down, this serum is the one product I never go without. It has two products stored separately. Use two fingers to dispense both, lightly mix together and pat all over. Face, neck, chest if you desire. Best results are achieved using twice a day, but now I mostly use this in the morning. Highly recommend this!
Report this reviewNot worth it
Saw no difference after using the entire bottle over months. For such an extreme price tag the difference should be night and day but sadly it missed the mark completely.
Report this reviewSticky/tacky
I wanted to love this for what it could be, but the texture wouldn't let me. It wouldn't absorb well enough to be layered without pilling which made putting make-up on over it pointless unless you wanted to look patchy. It also felt like when it dried down that my skin felt almost dehydrated. Tried it for 30 days hoping that it was just an adjustment period for my skin, but instead was an expensive toss. :(
Report this reviewEssential
This serum, although pricey, is a real game changer. Helps to maintain good texture and tone. Of all the expensive skin care items I’ve used, this is the one that really delivers significant results.
Report this review