Earn 2x points on SkinMedica. Plus, receive a SkinMedica Brightening Essentials Gift Set ($130 value) when you spend $200+ on the brand. START EARNING.

Wrinkle Creams and Fine Line Treatments

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  • Sponsored

    SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)

    Double Points + $130 Gift

    Earn 2x Dermstore Rewards Points on SkinMedica. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a SkinMedica Brightening Essentials Gift Set ($130 value) when you spend $200 or more on the brand. Complimentary gift will be awarded at the cart. SkinMedica event ends 5/14/24 at 11:59 p.m. PT.
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    $96.00
  • SkinCeuticals C E Ferulic

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    $182.00
  • Dr. Whitney Bowe Beauty Asta C Vitamin C Age Defense Serum (1 fl oz)

    Dermstore Exclusive

    This product is exclusive to Dermstore - a one-of-a-kind available nowhere else. Limited quantity available. 
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    $88.00
  • SkinCeuticals Triple Lipid Restore 242

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    $155.00
  • SkinMedica TNS Advanced+ Serum

    Double Points + $130 Gift

    Earn 2x Dermstore Rewards Points on SkinMedica. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a SkinMedica Brightening Essentials Gift Set ($130 value) when you spend $200 or more on the brand. Complimentary gift will be awarded at the cart. SkinMedica event ends 5/14/24 at 11:59 p.m. PT.
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    $295.00
  • iS Clinical Pro-Heal Serum Advance+

    iS Clinical Pro-Heal Serum Advance+ 3.75ml
    iS Clinical Pro-Heal Serum Advance+ 3.75ml Value $23.75

    $23 Gift

    Receive an iS Clinical Pro-Heal Serum Advance+ 3.75 ml (Worth $23) when you spend $150 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    $158.00
  • SkinMedica HA5 Rejuvenating Hydrator

    Double Points + $130 Gift

    Earn 2x Dermstore Rewards Points on SkinMedica. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a SkinMedica Brightening Essentials Gift Set ($130 value) when you spend $200 or more on the brand. Complimentary gift will be awarded at the cart. SkinMedica event ends 5/14/24 at 11:59 p.m. PT.
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    $184.00
  • Sunday Riley Good Genes All-In-One Lactic Acid Treatment 1.7oz

    Sunday Riley A+ High-Dose Retinoid Serum 5ml ($15 Value)
    Sunday Riley A+ High-Dose Retinoid Serum 5ml ($15 Value) Value $15.00

    $15 Gift

    Receive a Sunday Riley A+ High-Dose Retinoid Serum 5ml ($15 Value) when you spend $120 or more on the brand. Complimentary gift will be awarded at the cart.
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    $122.00
  • Dr. Whitney Bowe Beauty Retinal Night Advanced 0.1% Retinal Firming Treatment (0.95 fl oz)

    Dermstore Exclusive

    This product is exclusive to Dermstore - a one-of-a-kind available nowhere else. Limited quantity available. 
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    $99.00
  • SkinCeuticals Hyaluronic Acid Intensifier

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    $110.00
  • SkinCeuticals Hydrating B5 Gel

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    $90.00
  • SkinCeuticals Phloretin CF

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    $182.00
  • SkinCeuticals Blemish + Age Defense

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    $110.00
  • SkinCeuticals Phyto Corrective Gel

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    $80.00
  • SkinCeuticals Retinol 1.0 Maximum Strength Refining Night Cream

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    Dermstore is an authorized online retailer of SkinCeuticals.
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    $102.00
  • Cell Cycle Catalyst Exfoliating Booster Serum (1 fl. oz.)

    New Arrival

    Shop new arrivals to discover the latest in beauty, skin and hair care and stock up on seasonal must-haves and everyday essentials.
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    $115.00
  • SkinCeuticals Retinol 0.5

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    $90.00
  • SkinCeuticals Silymarin CF

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    $182.00
  • SkinCeuticals Resveratrol B E

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    $168.00
  • SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)

    Double Points + $130 Gift

    Earn 2x Dermstore Rewards Points on SkinMedica. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a SkinMedica Brightening Essentials Gift Set ($130 value) when you spend $200 or more on the brand. Complimentary gift will be awarded at the cart. SkinMedica event ends 5/14/24 at 11:59 p.m. PT.
    START EARNING
    $96.00
  • iS Clinical Active Serum

    iS Clinical Pro-Heal Serum Advance+ 3.75ml
    iS Clinical Pro-Heal Serum Advance+ 3.75ml Value $23.75

    $23 Gift

    Receive an iS Clinical Pro-Heal Serum Advance+ 3.75 ml (Worth $23) when you spend $150 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
    SHOP NOW
    $142.00
  • iS Clinical Pro-Heal Serum Advance+ 15ml

    iS Clinical Pro-Heal Serum Advance+ 3.75ml
    iS Clinical Pro-Heal Serum Advance+ 3.75ml Value $23.75

    $23 Gift

    Receive an iS Clinical Pro-Heal Serum Advance+ 3.75 ml (Worth $23) when you spend $150 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
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    $95.00
  • SkinCeuticals Glycolic 10 Renew Overnight (1.7 fl. oz.)

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    Dermstore is an authorized online retailer of SkinCeuticals.
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    $96.00
  • Peter Thomas Roth Water Drench Hyaluronic Cloud Hydra-Gel Eye Patches (30 pair)

    Peter Thomas Roth Peptide Skinjection Amplified Wrinkle-Fix Refillable Deluxe Serum 5ml (Worth $14.00)
    Peter Thomas Roth Peptide Skinjection Amplified Wrinkle-Fix Refillable Deluxe Serum 5ml (Worth $14.00) Value $14.00

    $14 Gift

    Receive a Peter Thomas Roth Peptide Skinjection Amplified Wrinkle-Fix Refillable Deluxe Serum 5ml ($14 value) when you spend $60 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid while supplies last.
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    $55.00
  • SkinMedica Age Defense Retinol Complex 0.5 (1 fl. oz.)

    Double Points + $130 Gift

    Earn 2x Dermstore Rewards Points on SkinMedica. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a SkinMedica Brightening Essentials Gift Set ($130 value) when you spend $200 or more on the brand. Complimentary gift will be awarded at the cart. SkinMedica event ends 5/14/24 at 11:59 p.m. PT.
    START EARNING
    $80.00
  • SkinCeuticals Metacell Renewal B3 (1.7 fl. oz.)

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    $130.00
  • Paula's Choice C15 Super Booster 20ml

    New Arrival

    Shop new arrivals to discover the latest in beauty, skin and hair care and stock up on seasonal must-haves and everyday essentials.
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    $55.00
  • SkinCeuticals Retexturing Activator (1 fl. oz.)

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    $94.00
  • SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)

    Double Points + $130 Gift

    Earn 2x Dermstore Rewards Points on SkinMedica. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a SkinMedica Brightening Essentials Gift Set ($130 value) when you spend $200 or more on the brand. Complimentary gift will be awarded at the cart. SkinMedica event ends 5/14/24 at 11:59 p.m. PT.
    START EARNING
    $64.00
  • SkinMedica Vitamin C + E Complex (1 oz.)

    Double Points + $130 Gift

    Earn 2x Dermstore Rewards Points on SkinMedica. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a SkinMedica Brightening Essentials Gift Set ($130 value) when you spend $200 or more on the brand. Complimentary gift will be awarded at the cart. SkinMedica event ends 5/14/24 at 11:59 p.m. PT.
    START EARNING
    $106.00
  • iS Clinical Active Serum 15ml

    iS Clinical Pro-Heal Serum Advance+ 3.75ml
    iS Clinical Pro-Heal Serum Advance+ 3.75ml Value $23.75

    $23 Gift

    Receive an iS Clinical Pro-Heal Serum Advance+ 3.75 ml (Worth $23) when you spend $150 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
    SHOP NOW
    $88.00
  • SkinMedica TNS Recovery Complex (1 fl. oz.)

    Double Points + $130 Gift

    Earn 2x Dermstore Rewards Points on SkinMedica. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a SkinMedica Brightening Essentials Gift Set ($130 value) when you spend $200 or more on the brand. Complimentary gift will be awarded at the cart. SkinMedica event ends 5/14/24 at 11:59 p.m. PT.
    START EARNING
    $230.00
  • SkinCeuticals AOX Eye Gel (0.5 fl. oz.)

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
    SHOP NOW
    $104.00
  • SkinMedica HA5 Rejuvenating Hydrator (1 fl. oz.)

    Double Points + $130 Gift

    Earn 2x Dermstore Rewards Points on SkinMedica. Double points = 10% back in rewards to spend on future purchases at Dermstore.com. Plus, receive a SkinMedica Brightening Essentials Gift Set ($130 value) when you spend $200 or more on the brand. Complimentary gift will be awarded at the cart. SkinMedica event ends 5/14/24 at 11:59 p.m. PT.
    START EARNING
    $124.00
  • iS Clinical Super Serum Advance Plus (1 fl. oz.)

    iS Clinical Pro-Heal Serum Advance+ 3.75ml
    iS Clinical Pro-Heal Serum Advance+ 3.75ml Value $23.75

    $23 Gift

    Receive an iS Clinical Pro-Heal Serum Advance+ 3.75 ml (Worth $23) when you spend $150 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid limited time only, while supplies last.
    SHOP NOW
    $158.00
  • SkinCeuticals Double Defense Kit: C E Ferulic + Daily Brightening UV Defense Sunscreen SPF 30

    Authorized Retailer Authorized Retailer

    Dermstore is an authorized online retailer of SkinCeuticals.
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    MSRP: $242.00
    $212.00
  • PCA SKIN Pro-Max Age Renewal Advanced Anti-Aging Serum with Micro Growth Factor Technology 1 oz

    New Arrival

    Shop new arrivals to discover the latest in beauty, skin and hair care and stock up on seasonal must-haves and everyday essentials.
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    $219.00
It happens to everyone, sooner or later. One day, you're admiring your smooth, tight and glowing skin in the mirror and (seemingly) the next day, your complexion has sprouted enough fine lines and wrinkles to cause you alarm. So what can you do? Browse our curated selection of wrinkle creams that include key ingredients like peptides, retinols and plant stem cells, all of which support and strengthen the growth, reproduction and revival of your skin cells. Drinking lots of water, quitting smoking and wearing sunscreen are also essential behavioral changes for anyone seeking a wrinkle-free complexion.