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Shop our bestsellers now to upgrade your routine with beauty's most efficacious formulas and tools.

Obagi Medical CLENZIderm M.D. Pore Therapy (4 oz.)

4.71 stars out of a maximum of 5

270 reviews

$49.00

iS Clinical Hydra-Cool Serum (1 oz.)

4.65 stars out of a maximum of 5

148 reviews

$103.00

ISDIN Eryfotona Ageless Mineral Broad-Spectrum Tinted Face Sunscreen SPF 50 (3.4 fl. Oz)

4.5 stars out of a maximum of 5

12 reviews

$78.00

EltaMD AM & PM Therapy Duo ($94 Value)

4.56 stars out of a maximum of 5

9 reviews

$85.00

Olaplex Shampoo and Conditioner Bundle

4.72 stars out of a maximum of 5

43 reviews

$60.00

SkinMedica Dermal Repair Cream (1.7 oz.)

4.73 stars out of a maximum of 5

279 reviews

$134.00

Elemis Pro-Collagen Cleansing Balm 100g

4.72 stars out of a maximum of 5

92 reviews

$69.00

Obagi Medical Nu-Derm Toner (6.7 oz.)

4.78 stars out of a maximum of 5

329 reviews

$49.00

Eminence Organic Skin Care Strawberry Rhubarb Hyaluronic Hydrator

4.79 stars out of a maximum of 5

24 reviews

$65.00

Eminence Organic Skin Care Stone Crop Cleansing Oil

4.78 stars out of a maximum of 5

101 reviews

$59.00

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2883 results

The Cyber Monday Skin Care Sale | Up to 30% off or 2x Points Has Ended

The sale may be over but get your favorites on Auto-Replenishment & never run out of your favorites *Hint: There maybe savings on our top brands*

15% Off20% Off25% Off30% OffMakeup Hair CareFragranceTools & DevicesLuxury BeautyGift SetsBestsellers
Eminence Organic Skin Care Clear Skin Probiotic Cleanser 8.4 fl. oz

4.62 stars out of a maximum of 5

262 reviews

$48.00

Colorescience Sunforgettable® Total Protection Face Shield SPF 50 (PA++++)- Classic

4.52 stars out of a maximum of 5

431 reviews

$52.00

Eminence Organic Skin Care Stone Crop Gel Wash 4.2 fl. oz

4.77 stars out of a maximum of 5

235 reviews

$48.00

Eminence Organic Skin Care Facial Recovery Oil 0.5 fl. oz

4.78 stars out of a maximum of 5

129 reviews

$85.00

Colorescience Sunforgettable Total Protection Color Balm 0.32oz. (Various Shades)

4.2 stars out of a maximum of 5

112 reviews

$42.00

La Roche-Posay Toleriane Purifying Foaming Cleanser (Various Sizes)

4.81 stars out of a maximum of 5

111 reviews

$17.99

Medik8 Super C Ferulic Serum 30ml

4.5 stars out of a maximum of 5

6 reviews

$75.00

ISDIN Eryfotona Actinica Mineral Broad-Spectrum Face Sunscreen SPF 50+ (1.7 fl. Oz)

5 stars out of a maximum of 5

1 reviews

$46.00

Dr. Dennis Gross Skincare Alpha Beta Extra Strength Daily Peel (Pack of 60)

4.84 stars out of a maximum of 5

49 reviews

$153.00

SkinCeuticals Hydrating B5 Mask (2.5 fl. oz.)

4.6 stars out of a maximum of 5

134 reviews

$70.00

Avène Thermal Spring Water (10.1 oz.)

4.82 stars out of a maximum of 5

343 reviews

$19.00

SkinCeuticals Face Cream (1.7 fl. oz.)

4.5 stars out of a maximum of 5

40 reviews

$156.00

SkinCeuticals Anti-Aging Firming Set with C E Ferulic Vitamin C

4.86 stars out of a maximum of 5

21 reviews

$298.00

Neostrata Skin Active Triple Firming Neck Cream New and Improved Formula with MicroDiPeptide229 80g

5 stars out of a maximum of 5

2 reviews

$98.00

Epionce Renewal Eye Cream (0.53 oz.)

4.72 stars out of a maximum of 5

123 reviews

$78.00

Revision Skincare® Papaya Enzyme Cleanser 6.7 fl. oz.

4.61 stars out of a maximum of 5

18 reviews

$45.00

Sunday Riley Auto Correct Brightening and Depuffing Eye Contour Cream 0.5 fl. oz.

4.29 stars out of a maximum of 5

153 reviews

$65.00

PCA SKIN Facial Wash (7 oz.)

4.71 stars out of a maximum of 5

181 reviews

$40.00

Dr. Diamond's Metacine INSTAFACIAL PLASMA Bioactive Growth Factor Serum (1 fl. Oz.)

$200.00

EltaMD Renew Eye Gel (0.5 fl. oz.)

4.53 stars out of a maximum of 5

302 reviews

$65.00

Epionce Gentle Foaming Cleanser (6 fl. oz.)

4.69 stars out of a maximum of 5

91 reviews

$36.00

SkinMedica Replenish Hydrating Cream (2 oz.)

4.78 stars out of a maximum of 5

123 reviews

$68.00

Avène Cicalfate+ Restorative Protective Cream (3.3 oz.)

4.59 stars out of a maximum of 5

81 reviews

$40.00

La Roche-Posay Toleriane Hydrating Gentle Cleanser (Various Sizes)

4.67 stars out of a maximum of 5

6 reviews

$8.49

Osmosis +Beauty StemFactor Growth Factor Serum 30ml

5 stars out of a maximum of 5

3 reviews

$136.00

PCA SKIN Hydrating Toner (7 fl. oz.)

4.72 stars out of a maximum of 5

116 reviews

$48.00

Dermalogica Daily Microfoliant Travel Size (0.45 oz.)

4.64 stars out of a maximum of 5

64 reviews

$19.00

SkinMedica TNS Ceramide Treatment Cream (2 oz.)

4.72 stars out of a maximum of 5

259 reviews

$72.00

Bioderma Sensibio H2O Micellar Water Duo (16.7 oz.)

5 stars out of a maximum of 5

3 reviews

$30.99

Epionce Daily Shield Lotion Tinted SPF 50 1.7 fl. oz.

4.68 stars out of a maximum of 5

133 reviews

$42.00

Eminence Organic Skin Care Clear Skin Probiotic Moisturizer 2 fl. oz

4.55 stars out of a maximum of 5

232 reviews

$65.00

Paula's Choice SKIN BALANCING Pore-Reducing Toner (6.4 fl. oz.)

4.45 stars out of a maximum of 5

71 reviews

$29.00

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Unlock transformative skincare this Black Friday with our exclusive deals at Dermstore. Explore a selection of dermatologist-approved products that emphasize both effective and safe ingredients. Our curated range features hard-to-find dermatology and spa items that deliver purposeful innovation and remarkable results. Don’t miss these Black Friday skin care deals—invest in your skincare routine with products designed to elevate your beauty experience and reveal your healthiest skin!