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Shop our bestsellers now to upgrade your routine with beauty's most efficacious formulas and tools.

La Roche-Posay Hyalu B5 Hyaluronic Acid Serum (Various Sizes)

4.33 stars out of a maximum of 5

6 reviews

$53.99

Revision Skincare® YouthFull Lip Replenisher 0.33 oz.

4.55 stars out of a maximum of 5

108 reviews

$42.00

Avène Cicalfate+ Restorative Protective Cream (3.3 oz.)

4.64 stars out of a maximum of 5

80 reviews

$40.00

Eminence Organic Skin Care Stone Crop Cleansing Oil

4.78 stars out of a maximum of 5

100 reviews

$59.00

Epionce Intensive Nourishing Cream (1.7 oz.)

4.76 stars out of a maximum of 5

93 reviews

$120.00

PCA Skin Hyaluronic Acid Overnight Mask 1.8 oz.

4.53 stars out of a maximum of 5

40 reviews

$84.00

Jan Marini Bioglycolic Face Cleanser (8 oz.)

4.8 stars out of a maximum of 5

231 reviews

$50.00

Obagi Medical ELASTIderm Facial Serum (1 oz.)

4.67 stars out of a maximum of 5

81 reviews

$215.00

SkinCeuticals Replenishing Cleanser (5 fl. oz.)

4.78 stars out of a maximum of 5

87 reviews

$39.00

Obagi Medical Nu-Derm Clear Fx (2 oz.)

4.55 stars out of a maximum of 5

158 reviews

$119.00

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2886 results

The Cyber Monday Skin Care Sale | Up to 30% off or 2x Points Has Ended

The sale may be over but get your favorites on Auto-Replenishment & never run out of your favorites *Hint: There maybe savings on our top brands*

15% Off20% Off25% Off30% OffMakeup Hair CareFragranceTools & DevicesLuxury BeautyGift SetsBestsellers
Obagi Medical Daily Hydro-Drops Facial Serum (1 oz.)

4.41 stars out of a maximum of 5

68 reviews

$110.00

iS Clinical Hydra-Cool Serum (1 oz.)

4.65 stars out of a maximum of 5

148 reviews

$103.00

Dr Dennis Gross Alpha Beta Universal Daily Peel (60 Pack)

4.9 stars out of a maximum of 5

30 reviews

$153.00

Eminence Organic Skin Care Stone Crop Hydrating Mist 4.2 fl. oz

4.7 stars out of a maximum of 5

223 reviews

$39.00

SkinCeuticals Clarifying Clay Mask (2.4 fl. oz.)

4.78 stars out of a maximum of 5

239 reviews

$70.00

Epionce Daily Shield Lotion Tinted SPF 50 1.7 fl. oz.

4.68 stars out of a maximum of 5

132 reviews

$42.00

Cell Cycle Catalyst Exfoliating Booster Serum (1 fl. oz.)

4.58 stars out of a maximum of 5

19 reviews

$115.00

Avène Thermal Spring Water (10.1 oz.)

4.82 stars out of a maximum of 5

343 reviews

$19.00

PCA SKIN Pro-Max Age Renewal Advanced Anti-Aging Serum with Micro Growth Factor Technology 1 oz

4.64 stars out of a maximum of 5

11 reviews

$221.00

Epionce Renewal Facial Cream (1.7 oz.)

4.81 stars out of a maximum of 5

130 reviews

$102.00

SkinCeuticals Epidermal Repair (1.35 fl. oz.)

4.88 stars out of a maximum of 5

104 reviews

$90.00

Medik8 Super C Ferulic Serum 30ml

4.5 stars out of a maximum of 5

6 reviews

$75.00

SkinMedica AHA/BHA Cream (2 oz.)

4.74 stars out of a maximum of 5

138 reviews

$46.00

Epionce Gentle Foaming Cleanser (6 fl. oz.)

4.72 stars out of a maximum of 5

90 reviews

$36.00

EltaMD UV Sheer Broad-Spectrum SPF 50 (1.7 fl. oz.)

4.47 stars out of a maximum of 5

90 reviews

$37.00

SkinCeuticals Equalizing Toner Solution (6.7 fl. oz.)

5 stars out of a maximum of 5

1 reviews

$38.00

SkinCeuticals Serum 10 AOX (1 fl. oz.)

4.6 stars out of a maximum of 5

164 reviews

$76.00

EltaMD Skin Restore Body Cream (8 oz)

4.62 stars out of a maximum of 5

93 reviews

$42.00

SkinCeuticals Hydra Balm Moisturizer Ointment (1.67 fl. oz.)

4.67 stars out of a maximum of 5

78 reviews

$25.00

Obagi Medical Obagi-C Fx System C-Clarifying Serum (1 oz.)

4.56 stars out of a maximum of 5

41 reviews

$140.00

Eminence Organic Skin Care Strawberry Rhubarb Hyaluronic Serum

4.59 stars out of a maximum of 5

408 reviews

$55.00

Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant - Trial Size (30ml)

4.52 stars out of a maximum of 5

48 reviews

$14.00

VI Derm Gentle Purifying Cleanser 4 fl. oz.

4.92 stars out of a maximum of 5

38 reviews

$44.00

EltaMD Skin Recovery Amino Acid Foaming Cleanser (1 oz.)

$15.00

SkinCeuticals Conditioning Clarifying Toner (6.8 fl. oz.)

4.64 stars out of a maximum of 5

112 reviews

$38.00

SkinCeuticals Metacell Renewal B3 (1.7 fl. oz.)

4.66 stars out of a maximum of 5

194 reviews

$130.00

PCA SKIN Hydrator Plus Broad Spectrum SPF 30 (1.7 fl. oz.)

4.84 stars out of a maximum of 5

25 reviews

$50.00

SkinCeuticals Clear Daily Soothing UV Defense Cream SPF 50 (1 fl. oz.)

3.91 stars out of a maximum of 5

11 reviews

$54.00

PCA SKIN Vitamin B3 Brightening Serum (1 fl. oz.)

4.64 stars out of a maximum of 5

47 reviews

$128.00

La Roche-Posay Anthelios Tinted Mineral Light Fluid SPF 50 (Various Shades)

4.48 stars out of a maximum of 5

21 reviews

$39.99

Dr. Dennis Gross Skincare Alpha Beta Extra Strength Daily Peel (Pack of 60)

4.84 stars out of a maximum of 5

49 reviews

$153.00

SkinMedica Pore Purifying Gel Cleanser (6 fl. oz.)

5 stars out of a maximum of 5

2 reviews

$48.00

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Unlock transformative skincare this Black Friday with our exclusive deals at Dermstore. Explore a selection of dermatologist-approved products that emphasize both effective and safe ingredients. Our curated range features hard-to-find dermatology and spa items that deliver purposeful innovation and remarkable results. Don’t miss these Black Friday skin care deals—invest in your skincare routine with products designed to elevate your beauty experience and reveal your healthiest skin!