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Neocutis BIO CREAM Overnight Smoothing Cream (1.69 fl. oz.)
A clinically advanced anti-aging moisturizer that firms and brightens.
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4 installments of $40.00 with Klarna Learn more
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4 installments of $40.00 with afterpay Learn more
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4 installments of $40.00 with sezzle Learn more
Neocutis BIO CREAM Overnight Smoothing Cream (formerly BIO CREAM Bio-Restorative Skin Cream) is ideally formulated for maturing, sensitive, stressed and irritated skin and features a naturally balanced blend of essential rejuvenating nutrients. Growth factors, antioxidants and matrix proteins, including collagen, revive skin while boosting firmness, elasticity and brightness. Skin appears more youthful as fine lines and wrinkles are visibly reduced.
Due to a manufacturer packaging change, item received may vary from product image.
Use once or twice daily or follow the recommendations of your skin professional. Store below 86F and do not expose to direct sunlight.
Application Area: Face, Neck
Ideal for these Concerns: Free Radical Damage, Hypersensitive Skin
Ingredient: Antioxidants, Dimethicone, Hyaluronic Acid, Peptides, Vitamin E
Moisturizers: Face Moisturizer
Preferences: Dermatologist Approved, Fragrance-Free
Skin Care: Moisturizers
Skin Type: Mature Skin, Sensitive Skin
Wellness | Internal Factors: Stress Solutions and Treatments
Water (Aqua), Octyldodecanol, Glyceryl Stearate, Decyl Oleate, Glycerin, Propylene Glycol, Wheat Germ Oil (Triticum Vulgare), Stearic Acid, Cetyl Alcohol, Ceteareth-20, Processed Skin Proteins (PSP), Myreth-3 Myristate, Ceteareth-12, Cetearyl Alcohol, Cetyl Palmitate, Tocopheryl Acetate, Dimethicone, Borage Seed Oil (Borago Officinalis), Carbomer, Triethanolamine, Methylparaben, Propylparaben, Glycosphingolipids, Phenoxyethanol, Disodium EDTA, BHT, Ethylparaben, Butylparaben, Methylisothiazolinone, Methylchloroisothiazolinone.
Frequently Bought Together



Total Price: $349.00
Add both to cart
Neocutis BIO CREAM Overnight Smoothing Cream (1.69 fl. oz.)
A clinically advanced anti-aging moisturizer that firms and brightens.
Earn 800 reward points when purchasing this product as a rewards member*
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Free delivery
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You control the frequency
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No commitment. Cancel or delay
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Payment will be taken every month. months.
$160.00
In stock
-Usually dispatched within 24 hours
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4 installments of $40.00 with Klarna Learn more
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4 installments of $40.00 with afterpay Learn more
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4 installments of $40.00 with sezzle Learn more
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Neocutis BIO CREAM Overnight Smoothing Cream (formerly BIO CREAM Bio-Restorative Skin Cream) is ideally formulated for maturing, sensitive, stressed and irritated skin and features a naturally balanced blend of essential rejuvenating nutrients. Growth factors, antioxidants and matrix proteins, including collagen, revive skin while boosting firmness, elasticity and brightness. Skin appears more youthful as fine lines and wrinkles are visibly reduced.
Due to a manufacturer packaging change, item received may vary from product image.
Use once or twice daily or follow the recommendations of your skin professional. Store below 86F and do not expose to direct sunlight.
Application Area: Face, Neck
Ideal for these Concerns: Free Radical Damage, Hypersensitive Skin
Ingredient: Antioxidants, Dimethicone, Hyaluronic Acid, Peptides, Vitamin E
Moisturizers: Face Moisturizer
Preferences: Dermatologist Approved, Fragrance-Free
Skin Care: Moisturizers
Skin Type: Mature Skin, Sensitive Skin
Wellness | Internal Factors: Stress Solutions and Treatments
Water (Aqua), Octyldodecanol, Glyceryl Stearate, Decyl Oleate, Glycerin, Propylene Glycol, Wheat Germ Oil (Triticum Vulgare), Stearic Acid, Cetyl Alcohol, Ceteareth-20, Processed Skin Proteins (PSP), Myreth-3 Myristate, Ceteareth-12, Cetearyl Alcohol, Cetyl Palmitate, Tocopheryl Acetate, Dimethicone, Borage Seed Oil (Borago Officinalis), Carbomer, Triethanolamine, Methylparaben, Propylparaben, Glycosphingolipids, Phenoxyethanol, Disodium EDTA, BHT, Ethylparaben, Butylparaben, Methylisothiazolinone, Methylchloroisothiazolinone.
Frequently Bought Together



Total Price: $349.00
Add both to cart
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
Reward members earn 50 points for every review written on verified purchases.
No better than my old moisturizer that's half the price
I tried this moisturizer for 5 months. I am prone to breakouts and even though it moisturizes my face and gives me a glow, it causes me to break out on my chin area. For the price I switched back to my old Clinique that doesn't cause breakouts and I ordered EltaMD to try.
Report this reviewOutstanding for skin healing
My doctor recommended Neocutis for recovery from a microneedling session for scars. It made all the difference, and had a noticeable impact on my skin texture, moisture, and ability to heal. I'll use it in the future for any and all microneedling treatments.
Report this reviewSilky
This overnight serum needs to be applied heavier than normal creams, but definitely delivers silky feeling skin in the morning.
Report this reviewNeocutis night cream
This smoothing cream seems to really help my face feel silkier in the morning. I apply fairly heavy for best results
Report this reviewThe best thing for my skin
I love this product. It really transformed my skin and I keep reordering.
Report this reviewExpensive but good
This is pretty pricey but does a nice job. Good for sensitive skin and a bottle goes a long way!
Report this reviewMagnificent in Maintaining Marvelous Skin
I have been using Neocutis Bio Cream Overnight Smoothing Cream for several years and my skin has maintained a soft texture and even tone. It gets more challenging with advancing age to keep up a youthful appearance. This product actually helps slow down the loss of firmness and wrinkles that inevitably happen as we age. Along with a healthy lifestyle, I have a regular skin regime that includes excellent products such as Neocutis Bio Cream. The application for overnight makes it all the more effective while your body rests and repairs itself.
Report this reviewBio cream
I love this cream. It’s intense moisture softens and adds a glow to my skin.
Report this reviewThis cream is FABULOUS
Been using this overnight cream since the pandemic and it's really made a difference! My skin is more hydrated and looks brighter, it's reduced fine lines; the areas around my mouth and near the jaw even seem firmer. You don't need to use a lot. LOVE NEOCUTIS products...in my opinion, they are worth every penny!
Report this reviewEffective & Light
I really like this cream by Neocutis. It has a light weight texture, a little goes a long way and skin is treated during sleep which effectively yields great results. My skin is soft, with an even tone. It also helps to minimize wrinkles and slow down the loss of elasticity due to aging. I highly recommend Neocutis Bio Cream for overnight treatment of the face, neck and décolleté.
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