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Paula's Choice CLINICAL Niacinamide 20 Treatment (0.67 fl. oz.)
A highly concentrated serum that improves the skin's tone and texture.
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4 installments of $10.62 with Klarna Learn more
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4 installments of $10.62 with afterpay Learn more
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4 installments of $10.62 with sezzle Learn more
Achieve a smoother and more radiant complexion with CLINICAL Niacinamide 20% Treatment from Paula's Choice. This advanced, concentrated serum helps to tighten and minimize the appearance of pores and rough bumps caused by age or sun damage. Niacinamide normalizes pore function and protects from further stretching when exposed to damaging UV light, resulting in improved radiance and texture.
Key Ingredients:
- 20% Niacinamide (Vitamin B3): minimizes enlarged pores, improves uneven skin tone and promotes a smooth, blemish-free complexion
- Acetyl Glucosamine: brightens skin tone and steadily refines skin texture
- Vitamin C: visibly improves the look of uneven skin tone and discoloration
- Green Tea: helps defend and repair skin damaged by UV light, airborne pollutants and other environmental aggressors
Key Benefits:
- Dramatically reduces the look of stretched pores
- Helps reduce hard clogged bumps and orange-peel texture
- Visibly improves blotchy tone and fades post-blemish marks
Apply a few drops once or twice daily after cleansing, toning and exfoliating. At night, layer with other treatment products as needed and follow with moisturizer; during the day, finish with a sunscreen rated SPF 30 or greater.
Acne: Acne Scars
Application Area: Face
Ingredient: Green Tea, Niacinamide
Preferences: Hypoallergenic, Oil-Free
Skin Care Treatments: Face Serums
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water (Aqua), Niacinamide, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra (Licorice) Root Extract, Spiraea Ulmaria (Meadowsweet) Extract, Portulaca Oleracea (Purslane) Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis (Green Tea) Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin.
Frequently Bought Together



Total Price: $93.50
Add both to cart
Paula's Choice CLINICAL Niacinamide 20 Treatment (0.67 fl. oz.)
A highly concentrated serum that improves the skin's tone and texture.
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MSRP: $50.00
$42.50
Save: $7.50
In stock
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4 installments of $10.62 with Klarna Learn more
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4 installments of $10.62 with afterpay Learn more
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4 installments of $10.62 with sezzle Learn more
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Achieve a smoother and more radiant complexion with CLINICAL Niacinamide 20% Treatment from Paula's Choice. This advanced, concentrated serum helps to tighten and minimize the appearance of pores and rough bumps caused by age or sun damage. Niacinamide normalizes pore function and protects from further stretching when exposed to damaging UV light, resulting in improved radiance and texture.
Key Ingredients:
- 20% Niacinamide (Vitamin B3): minimizes enlarged pores, improves uneven skin tone and promotes a smooth, blemish-free complexion
- Acetyl Glucosamine: brightens skin tone and steadily refines skin texture
- Vitamin C: visibly improves the look of uneven skin tone and discoloration
- Green Tea: helps defend and repair skin damaged by UV light, airborne pollutants and other environmental aggressors
Key Benefits:
- Dramatically reduces the look of stretched pores
- Helps reduce hard clogged bumps and orange-peel texture
- Visibly improves blotchy tone and fades post-blemish marks
Apply a few drops once or twice daily after cleansing, toning and exfoliating. At night, layer with other treatment products as needed and follow with moisturizer; during the day, finish with a sunscreen rated SPF 30 or greater.
Acne: Acne Scars
Application Area: Face
Ingredient: Green Tea, Niacinamide
Preferences: Hypoallergenic, Oil-Free
Skin Care Treatments: Face Serums
Skin Type: Acne-Prone Skin, Combination Skin, Dry Skin, Mature Skin, Normal Skin, Oily Skin, Sensitive Skin
Water (Aqua), Niacinamide, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra (Licorice) Root Extract, Spiraea Ulmaria (Meadowsweet) Extract, Portulaca Oleracea (Purslane) Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis (Green Tea) Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin.
Frequently Bought Together



Total Price: $93.50
Add both to cart
Customer Reviews
Top Customer Reviews
Where reviews refer to beauty products or supplements, results may vary from person to person. Customer reviews are independent and do not represent the views of Dermstore.
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Decent product!
Liked how the product went on my skin—much less sticky than other niacinamide serums i’ve tried in the past. Not sure if I think it significantly changed my skin texture or acne but also didn’t irritate or make worse.
Report this reviewGame changer
This is what made my enlarged pores unable to be seen without a magnifying mirror. My nose pores stay completely clean and my nose looks poreless. I've always tried many products, and my enlarged pores have always been an issue I've tried to better, but this one was the game changer. I now have the results I sought for years.
Report this reviewGood, but not that good
Its okay, honestly but I dont think it is working for me, and I wont repurchase it
Report this reviewBUY IT
This product has really helped smooth out my skin! Will continue to repurchase
Report this reviewBreakouts
Unfortunately this product caused me to break out… a lot. Not sure if my skin is just purging and I need to give it more of a try but scared to just keep breaking out more.
Report this reviewHarsh on sensitive skin
This caused major redness and dryness, even after diluting it with other products for application. I had to reduce how frequently I was using it, but it still was making my face red and ultimately I had to phase out altogether. I did not see any results in pore size or skin texture.
Report this reviewGood but not for sensitive skin!
Wanted to love this but my sensitive skin did not. Too much redness and irritation for me. Use in moderation!
Report this reviewGreat stuff!
I've used another brand's 10% solution for a few weeks and liked the results I was getting. Saw Paula's Choice 20%, thought I would try that and wow what a difference in my face. It is like getting a mini facelift. I've been using it for about a month now and people think I've had "work" done on my face. It says results show in 8 weeks, can't wait to see what happens to my face in another months time. I will have to say my face looks equal or better than when I used Skin Medica's TNS recovery and that costs 4x as much. Definitely on my "keep using" list.
Report this reviewPaula choice CLINICAl Niaciamide20
I use this For the first time I haven’t had any problems, I like the texture of this it is not sticky and not oily, so it seems to be working. I know niacinamide is great for skin
Report this reviewLOVE
This does a great job of restoring my moisture barrier and minimizing pores!
Report this review