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Face Serums

783 results

Our collection of serums features formulas made with top-quality, efficacious ingredients including vitamins C and E, hyaluronic acid, alpha and beta hydroxy acids and more. Serums often feature high concentrations of active ingredients for maximum results, and work well as a step between a toner and moisturizer. Brighten, repair and renew your skin.

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Products

  • Sponsored

    111SKIN Cryo De-Puffing Energy Mask Box (Pack of 5)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $135.00
  • Sponsored

    Obagi Medical Obagi-C Fx System C-Clarifying Serum (1 fl. oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $135.00
  • Sponsored

    Obagi Medical Daily Hydro-Drops Facial Serum (1 fl. oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $105.00
  • SkinCeuticals C E Ferulic

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
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    $182.00
  • Dr. Whitney Bowe Beauty Asta C Vitamin C Age Defense Serum (1 fl oz)

    Dermstore Exclusive

    This product is exclusive to Dermstore - a one-of-a-kind available nowhere else. Limited quantity available. 
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    $88.00
  • SkinMedica TNS Advanced+ Serum

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
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    $295.00
  • Neocutis BIO SERUM FIRM Rejuvenating Growth Factor & Peptide Treatment

    20% off Auto-Replenishment

    Enjoy 20% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $290.00
  • PCA SKIN Hyaluronic Acid Boosting Serum

    20% off Auto-Replenishment

    Enjoy 20% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $125.00
  • Revision Skincare® Retinol Complete 1.0 1 oz.

    Auto-Replenishment

    Enjoy your favorites at your ferquency. Not only do you choose your frequency, but you get FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $134.00
  • Sunday Riley C.E.O. 15% Vitamin C Brightening Serum 1 fl. oz

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $85.00
  • Augustinus Bader The Retinol Serum 30ml

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $375.00
  • PCA SKIN Pro-Max Age Renewal Advanced Anti-Aging Serum with Micro Growth Factor Technology 1 oz

    New Arrival

    Shop new arrivals to discover the latest in beauty, skin and hair care and stock up on seasonal must-haves and everyday essentials.
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    $219.00
  • Dr. Whitney Bowe Beauty Retinal Night Advanced 0.1% Retinal Firming Treatment (0.95 fl oz)

    Dermstore Exclusive

    This product is exclusive to Dermstore - a one-of-a-kind available nowhere else. Limited quantity available. 
    VIEW ALL EXCLUSIVES
    $99.00
  • Eminence Strawberry Rhubarb Hyaluronic Hydrator

    Eminence Organic Skin Care Gift

    For a limited time, receive your choice of a full sized gift from Eminence Organic Skin Care free when you spend $145 on 2 or more Eminence Organic Skin Care products. Choose gift at cart. Offer valid limited time only.
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    $65.00
  • EltaMD Skin Recovery Serum (1 fl. oz.)

    Authorized Retailer

    Dermstore is an authorized online retailer of EltaMD.
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    $66.00
  • Obagi Medical ELASTIderm Facial Serum (1 fl. oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $215.00
  • SkinCeuticals Hyaluronic Acid Intensifier

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
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    $110.00
  • Eminence Organic Skin Care Strawberry Rhubarb Hyaluronic Serum

    Eminence Organic Skin Care Gift

    For a limited time, receive your choice of a full sized gift from Eminence Organic Skin Care free when you spend $145 on 2 or more Eminence Organic Skin Care products. Choose gift at cart. Offer valid limited time only.
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    $55.00
  • iS Clinical Active Serum

    iS Clinical Active Serum 3.75ml (Worth $22.00)
    iS Clinical Active Serum 3.75ml (Worth $22.00) Value $22.00

    $22 Gift

    Receive an iS Clinical Active Serum 3.75ml ($22 value) when you spend $125 or more on the brand. Complimentary Gift will be awarded in cart, while supplies last. Participating products only.
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    $142.00
  • Jan Marini C-ESTA Face Serum (1 fl. oz.)

    Auto-Replenishment

    Enjoy your favorites at your ferquency. Not only do you choose your frequency, but you get FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $129.00
  • SENTÉ Bio Complete Serum (1 oz.)

    Auto-Replenishment

    Enjoy your favorites at your ferquency. Not only do you choose your frequency, but you get FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $118.00
  • Sunday Riley Good Genes All-In-One Lactic Acid Treatment 1.7oz

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $122.00
  • Eminence Organic Skin Care Clear Skin Willow Bark Booster-Serum 1 fl. oz

    Eminence Organic Skin Care Gift

    For a limited time, receive your choice of a full sized gift from Eminence Organic Skin Care free when you spend $145 on 2 or more Eminence Organic Skin Care products. Choose gift at cart. Offer valid limited time only.
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    $64.00
  • Sunday Riley A+ High-Dose Retinoid Serum 30ml

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $85.00
  • SkinCeuticals Silymarin CF

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
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    $182.00
  • SkinCeuticals Retinol 1.0 Maximum Strength Refining Night Cream

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
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    $102.00
  • SkinMedica HA5 Rejuvenating Hydrator

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
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    $184.00
  • SkinCeuticals Hydrating B5 Gel

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
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    $90.00
  • SkinCeuticals Phyto Corrective Gel

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
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    $80.00
  • Paula's Choice CLINICAL 1% Retinol Treatment (1 fl. oz.)

    Paula's Choice Clarify and Even Duo ($14 Value)
    Paula's Choice Clarify and Even Duo ($14 Value) Value $14.00

    $14 Gift

    Receive a Paula's Choice Clarify and Even Duo ($14 value) when you spend $50 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    $65.00
  • Paula's Choice CLINICAL Niacinamide 20% Treatment (0.67 fl. oz.)

    Paula's Choice Clarify and Even Duo ($14 Value)
    Paula's Choice Clarify and Even Duo ($14 Value) Value $14.00

    $14 Gift

    Receive a Paula's Choice Clarify and Even Duo ($14 value) when you spend $50 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    $55.00
  • PCA SKIN Hyaluronic Acid Boosting Serum 3oz

    20% off Auto-Replenishment

    Enjoy 20% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $315.00
  • PCA SKIN Vitamin B3 Brightening Serum (1 fl. oz.)

    20% off Auto-Replenishment

    Enjoy 20% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $125.00
  • Peter Thomas Roth Anti-Aging Cleansing Gel (8.5 fl. oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $39.00
  • SkinCeuticals Triple Lipid Restore 242

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
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    $155.00
  • Obagi Medical Professional-C Serum 20%

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $142.00
  • Obagi Medical Professional-C Serum 15% (1 fl. oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $115.00
  • SkinCeuticals Phloretin CF

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
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    $182.00
  • SkinCeuticals Blemish + Age Defense

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
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    $110.00
  • SkinCeuticals Discoloration Defense

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $110.00
  • Obagi Medical Retinol 1.0 (1 oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $79.00
  • iS Clinical Pro-Heal Serum Advance+ 30ml

    iS Clinical Active Serum 3.75ml (Worth $22.00)
    iS Clinical Active Serum 3.75ml (Worth $22.00) Value $22.00

    $22 Gift

    Receive an iS Clinical Active Serum 3.75ml ($22 value) when you spend $125 or more on the brand. Complimentary Gift will be awarded in cart, while supplies last. Participating products only.
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    $158.00
  • Revision Skincare C+ Correcting Complex 30%

    Auto-Replenishment

    Enjoy your favorites at your ferquency. Not only do you choose your frequency, but you get FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $185.00
  • SkinMedica Even and Correct Brightening Treatment Pads - 60 Pads

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
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    $60.00
  • Sunday Riley C.E.O. 15% Vitamin C Brightening Serum 50ml

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $122.00
  • SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)

    SkinMedica Mini Method Kit (Worth $150.00)
    SkinMedica Mini Method Kit (Worth $150.00) Value $150.00

    $150 Gift

    Receive a SkinMedica Mini Method Kit ($150 value) when you spend $250 or more on the brand. Complimentary gift will be awarded at the cart, while supplies last.
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    $96.00
  • SkinCeuticals Resveratrol B E

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $168.00
  • Obagi Medical Daily Hydro-Drops Facial Serum (1 fl. oz.)

    15% off Auto-Replenishment

    Enjoy 15% off on your must-have products. Not only do you save on your initial purchase, but you save on your replenished purchases as well. Plus, FREE delivery on Auto-Replen orders after the first order. Select Auto-Replenish on the product page to start your Auto-Replenishment journey. 
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    $105.00
  • iS Clinical Hydra-Cool Serum

    iS Clinical Active Serum 3.75ml (Worth $22.00)
    iS Clinical Active Serum 3.75ml (Worth $22.00) Value $22.00

    $22 Gift

    Receive an iS Clinical Active Serum 3.75ml ($22 value) when you spend $125 or more on the brand. Complimentary Gift will be awarded in cart, while supplies last. Participating products only.
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    $99.00
  • SkinCeuticals Retinol 0.5

    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00)
    SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml (Worth $8.00) Value $8.00

    SkinCeuticals Gift

     Receive a complimentary SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml ($8 value) when you spend $175 or more on the brand. 
    SHOP NOW
    $90.00