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Face Serums

853 results

Our collection of serums features formulas made with top-quality, efficacious ingredients including vitamins C and E, hyaluronic acid, alpha and beta hydroxy acids and more. Serums often feature high concentrations of active ingredients for maximum results, and work well as a step between a toner and moisturizer. Brighten, repair and renew your skin.

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Products

  • SkinCeuticals C E Ferulic (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.76 Stars 4412 Reviews
    $169.00
  • Sunday Riley GOOD GENES Glycolic Acid Treatment (1.7 fl. oz.)

    4.57 Stars 69 Reviews
    $122.00
  • SkinMedica TNS Advanced+ Serum (1 oz.)

    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26)
    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26) Value $29.00

    $29 SkinMedica Gift

    Receive a Skinmedica Vitamin C+E Complex 0.25 oz ($29 value) when you spend $160 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.57 Stars 223 Reviews
    $295.00
  • Obagi Medical ELASTIderm Facial Serum (1 fl. oz.)

    4.61 Stars 41 Reviews
    $198.00
  • Eminence Organic Skin Care Strawberry Rhubarb Hyaluronic Serum 1 fl. oz

    4.61 Stars 339 Reviews
    $48.00
  • SkinCeuticals Blemish + Age Defense (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.7 Stars 605 Reviews
    $96.00
  • Sunday Riley JUNO Antioxidant + Superfood Face Oil (0.5 oz.)

    4.65 Stars 83 Reviews
    $36.00
  • Paula's Choice CLINICAL Niacinamide 20 Treatment (0.67 fl. oz.)

    4.56 Stars 43 Reviews
    $50.00
  • Obagi Medical Professional-C Serum 20% (1 fl. oz.)

    4.74 Stars 866 Reviews
    $136.99
  • SkinMedica TNS Essential Serum (1 oz.)

    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26)
    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26) Value $29.00

    $29 SkinMedica Gift

    Receive a Skinmedica Vitamin C+E Complex 0.25 oz ($29 value) when you spend $160 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.62 Stars 584 Reviews
    $281.00
  • Peter Thomas Roth Water Drench Hyaluronic Cloud Serum (1 oz.)

    4.24 Stars 25 Reviews
    $65.00
  • Sunday Riley C.E.O. Glow Vitamin C Turmeric Face Oil (1.18 fl. oz.)

    4.55 Stars 131 Reviews
    $80.00
  • Sunday Riley GOOD GENES All-In-One Lactic Acid Treatment (1.7 oz. - $175 Value)

    4.65 Stars 655 Reviews
    $122.00
  • PCA SKIN Hyaluronic Acid Boosting Serum (1 oz.)

    PCA SKIN Rejuvenate and Hydrate Duo
    PCA SKIN Rejuvenate and Hydrate Duo Value $33.50

    $32 PCA Skin Gift

    Receive a PCA SKIN Rejuvenate and Hydrate Duo (worth $32) when you spend $100 on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.76 Stars 235 Reviews
    $120.00
  • Revision Skincare® Hydrating Serum 1 fl. oz.

    4.81 Stars 78 Reviews
    $90.00
  • Sunday Riley JUNO Antioxidant + Superfood Face Oil (1.18 fl. oz.)

    4.52 Stars 94 Reviews
    $72.00
  • Eminence Organic Skin Care Clear Skin Willow Bark Booster-Serum 1 fl. oz

    4.57 Stars 68 Reviews
    $56.00
  • Revision Skincare® Retinol Complete 1.0 1 oz.

    5.0 Stars 5 Reviews
    $122.00
  • Caudalie Beauty Elixir (3.4 fl. oz.)

    4.48 Stars 84 Reviews
    $49.00
  • Caudalie Resveratrol-Lift Instant Firming Serum (1 fl. oz.)

    5.0 Stars 3 Reviews
    $79.00
  • PCA SKIN Total Strength Serum (1 fl. oz.)

    PCA SKIN Rejuvenate and Hydrate Duo
    PCA SKIN Rejuvenate and Hydrate Duo Value $33.50

    $32 PCA Skin Gift

    Receive a PCA SKIN Rejuvenate and Hydrate Duo (worth $32) when you spend $100 on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.83 Stars 18 Reviews
    $98.00
  • SkinCeuticals Triple Lipid Restore 242 (1.6 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.8 Stars 1655 Reviews
    $136.00
  • SkinCeuticals Hydrating B5 Gel (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.69 Stars 897 Reviews
    $86.00
  • SkinMedica HA5 Rejuvenating Hydrator (2 oz.)

    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26)
    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26) Value $29.00

    $29 SkinMedica Gift

    Receive a Skinmedica Vitamin C+E Complex 0.25 oz ($29 value) when you spend $160 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.7 Stars 509 Reviews
    $184.00
  • SkinCeuticals Phloretin CF (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.73 Stars 616 Reviews
    $169.00
  • SkinCeuticals Discoloration Defense (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.37 Stars 417 Reviews
    $102.00
  • SkinMedica Age Defense Retinol Complex 1.0 (1 fl. oz.)

    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26)
    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26) Value $29.00

    $29 SkinMedica Gift

    Receive a Skinmedica Vitamin C+E Complex 0.25 oz ($29 value) when you spend $160 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.84 Stars 263 Reviews
    $96.00
  • SkinMedica Lytera 2.0 Pigment Correcting Serum (2 oz.)

    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26)
    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26) Value $29.00

    $29 SkinMedica Gift

    Receive a Skinmedica Vitamin C+E Complex 0.25 oz ($29 value) when you spend $160 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.42 Stars 281 Reviews
    $160.00
  • iS Clinical Active Serum (1 fl. oz.)

    4.64 Stars 440 Reviews
    $142.00
  • SkinCeuticals Phyto Corrective Gel (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.55 Stars 427 Reviews
    $70.00
  • iS Clinical Pro-Heal Serum Advance Plus (1 fl. oz.)

    4.7 Stars 293 Reviews
    $158.00
  • SkinMedica Age Defense Retinol Complex 0.5 (1 fl. oz.)

    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26)
    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26) Value $29.00

    $29 SkinMedica Gift

    Receive a Skinmedica Vitamin C+E Complex 0.25 oz ($29 value) when you spend $160 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.81 Stars 270 Reviews
    $80.00
  • SkinCeuticals Retinol 1.0 Maximum Strength Refining Night Cream (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.71 Stars 415 Reviews
    $92.00
  • EltaMD UV Sheer Broad-Spectrum SPF 50 (1.7 fl. oz.)

    4.33 Stars 54 Reviews
    $32.00
  • SkinCeuticals Resveratrol B E (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.65 Stars 284 Reviews
    $156.00
  • SkinCeuticals Retinol 0.5 Refining Night Cream (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.78 Stars 344 Reviews
    $80.00
  • Paula's Choice C15 Super Booster (0.67 fl. oz.)

    4.49 Stars 214 Reviews
    $52.00
  • SkinCeuticals Silymarin CF (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.36 Stars 76 Reviews
    $169.00
  • SkinMedica Age Defense Retinol Complex .25 (1 fl. oz.)

    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26)
    SkinMedica Vitamin C+E Complex 0.25 oz (Worth $26) Value $29.00

    $29 SkinMedica Gift

    Receive a Skinmedica Vitamin C+E Complex 0.25 oz ($29 value) when you spend $160 or more on the brand. Complimentary gift will be awarded at the cart. Offer valid for a limited time only, while supplies last.
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    4.8 Stars 217 Reviews
    $64.00
  • SkinCeuticals Retinol 0.3 (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.79 Stars 216 Reviews
    $70.00
  • iS Clinical Hydra-Cool Serum (1 fl. oz.)

    4.67 Stars 117 Reviews
    $96.00
  • SkinCeuticals Retexturing Activator (1 fl. oz.)

    SkinCeuticals Discoloration Defense 4ml
    SkinCeuticals Discoloration Defense 4ml Value $13.00

    Earn Double Points + $13 SkinCeuticals Gift

    Earn 2x Dermstore Rewards Points on Skinceuticals. Participating products only. Plus, receive a SkinCeuticals Daily Brightening UV Defense Sun Cream SPF 30 4ml with any $150 purchase from the brand. Gift will be awarded at the cart. Skinceuticals event ends 5/21/2022 at 11:59 p.m. PT.
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    4.61 Stars 189 Reviews
    $86.00
  • Obagi Medical Retinol 1.0 (1 oz.)

    4.67 Stars 298 Reviews
    $77.50
  • Obagi Medical Professional-C Serum 15% (1 fl. oz.)

    4.79 Stars 389 Reviews
    $110.00