Earn 2x points on SkinMedica | TWO Free Gifts when you spend $200+ on your purchase. SHOP NOW
FREE US Shipping $50+ Auto-Replenishment 15% off first App Order Dermstore Rewards
SkinMedica

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

A powerful anti-aging serum that targets fine lines, deep wrinkles and sagging skin.

Rewards members earn 2950 points on this order. Register & opt in at checkout.

Join Dermstore Rewards

$295.00

Or 4 interest free payments of $73.75 with


In stock | Usually dispatched within 24 hours

Image 1 - Image of a skin serum bottle labeled TNS® ADVANCED+ SERUM with a background of glass beakers, featuring the text Next Generation Skin Rejuvenation and additional claims such as Clinically proven to address sagging skin, Smooths visible coarse wrinkles and fine lines, and Results start in just 2 weeks*.
Image 2 - Image showing a side-by-side comparison of a 60-year-old females face before and after using TNS Advanced+ serum, with the Before image on the left showing visible wrinkles and the After image on the right indicating smoother skin with marked improvements at week 2, alongside text detailing baseline and improvements.
Image 3 - Image shows a cream or gel texture with text highlighting key ingredients for skincare. Visible text includes: Key Ingredients TNS-MR An advanced formula to help you get age-defying results with: + NEXT-GENERATION GROWTH FACTOR BLEND Supports healthy skin functions + INNOVATIVE PEPTIDE COMPLEX Nourishes your skin Renessence (RSC) Advanced Specifically designed to support the results of the growth factor blend and includes: + MARINE EXTRACT Supports skin’s renewal process + GREEN MICROALGAE Supports collagen and elastin levels.
Image 4 - A sleek bottle of SkinMedica TNS Advanced+ Serum is displayed next to a small amount of the serum on a light background, with the text stating that in a clinical study, after 12 weeks, patients using the serum felt they looked up to 6 years younger.
Image 5 - A pair of hands holds a cosmetic bottle with instructions on its use, including details on when and how to apply the product, and visible text that reads: How to Use, WHEN TO APPLY, In the morning and evening after cleansing and toning, HOW TO APPLY, Before applying, invert and tap the bottom of the bottle, Remove the cap and press on the center of the pump to dispense onto the back of your hand using a bunny finger application, Blend the product together before applying, Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with warm water.
Image 6 - Image of SkinMedica products arranged on a light background, including an AHA/BHA Exfoliating Cleanser, TNS Advanced+ Serum, Instant Bright Eye Cream, HA⁵ Hydra Collagen Replenish + Restore Hydrator, and Essential Defense Mineral Shield Broad Spectrum SPF 35 Sunscreen, with the text Complete Your SkinMedica Method Routine above them.

Delivery & Returns
Free delivery is available on all orders over $50. Please see our shipping information page for all available delivery options.
If I'm not completely happy with my item?
Please see our returns policy.
*points earned on final checkout price, after any applied discounts.

Frequently Bought Together

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

This item

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

$295.00

Total Price:

$479.00

Other Customers Bought

Customer Reviews

4.55 stars out of a maximum of 5

5 stars rating 441 reviews

4 stars rating 82 reviews

3 stars rating 32 reviews

2 stars rating 12 reviews

1 stars rating 20 reviews

Top Customer Reviews

Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

Worth every dime!

5 stars out of a maximum of 5

My plastic surgeon  who does my Botox highly recommended this product. I had a bit of a sticker shock when I saw the price; however, being able to AfterPay it made it much more appealing. I have been using this product now going on 2 years and I simply love it! People will pay a lot of money for purses, clothes, etc. but will pause at spending $ on themselves. Investing in the only face/body you will ever get is worth it!!

by Kelly Verified Purchase

Was this helpful?

TNS Holy Grail Serum

5 stars out of a maximum of 5

I absolutely love this product since the moment I tried it and won't be without it. It goes on like a dream and every day helps your skin look a little better. A must have. A recommendation from my plastic surgeon who is a top surgeon in Boca Raton.

by lisaamy Verified Purchase

Was this helpful?

Pricey but effective

4 stars out of a maximum of 5

This serum  is at a high price point.  It’s ingredients are effective.  And the results are good. Recommended usage is 2X per day,  which means it will only last about a month.    I would have given 5 stars,  but the price point is quite high,  so gave it 4 stars.    I am 68 years old and this is part of my regular routine.  I cut back to only using 1X per day to help defray cost a bit.

by Rebecca Verified Purchase

Was this helpful?

Good for your Skin

5 stars out of a maximum of 5

Love, Love,Love this product! My skin loves it and it layers well with other products. Feed your skin!

by DD Verified Purchase

Was this helpful?

Nice product

5 stars out of a maximum of 5

About 3 weeks into use and the product has made my skin feel amazing. I know after about 12 weeks will be the true test but initial results show smoother, supple, moisturized skin

by pjd Verified Purchase

Was this helpful?

Game changer

5 stars out of a maximum of 5

I am on my second bottle of this product so I feel I can give an accurate review. This product (as well as any growth serum) takes time to see the benefits. It is expensive but with Skin Medica you get what you pay for. My wrinkles and texture have improved so much. If you only chose one product to use, hand down to his one. 

by Jessalynne Verified Purchase

Was this helpful?

WOW

5 stars out of a maximum of 5

I’ve been using this product for a week and I can already see differences in my skins overall texture, fine lines , and wrinkles. It is fully worth the price. I’ve been glowing ever since I started using it in my day and night skincare routine.

by Marissa Verified Purchase

Was this helpful?

In love!!

5 stars out of a maximum of 5

I’ve been using this serum for months and my skin looks amazing!! So many compliments on how pretty I look. Thank you TNS!!! I’m now on a subscription!!

by Kristen Verified Purchase

Was this helpful?

Liquid Gold

5 stars out of a maximum of 5

This product is amazing. Once I put it on my skin, my skin feels so soft and silky.  I wish they made it for your whole body. I will never stop using this.  

by Donna Verified Purchase

Was this helpful?

Noticed a difference

5 stars out of a maximum of 5

I noticed a difference in skin texture in a few weeks. Look forward to using the product long term to see the full benefits. No issues with the dispenser as some others noted, but I do tap the bottle a few times on the bottom before dispensing the product as suggested on one of their sites. 

by Katie Verified Purchase

Was this helpful?